Olopatadine Nasal Side Effects

Medically reviewed by Drugs.com. Last updated on May 6, 2024.

Applies to olopatadine nasal: nasal spray.

Precautions

It is very important that your doctor check you or your child at regular visits for any problems or unwanted effects that may be caused by this medicine.

This medicine may increase your risk of having nasal problems. Check with your doctor right away if you or your child have bloody mucus; sores inside the nose; or unexplained nosebleeds while you are using this medicine.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your medical doctor or dentist before taking any of the medicines above while you or your child are using this medicine.

This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. If any of these side effects occur, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

If your or your child's symptoms do not improve within a few days or if they become worse, check with your doctor.

Common side effects of olopatadine nasal

Some side effects of olopatadine nasal may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects of olopatadine nasal

Along with its needed effects, olopatadine nasal may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking olopatadine nasal:

Get emergency help immediately if any of the following symptoms of overdose occur while taking olopatadine nasal:

Symptoms of overdose

• anxiety
• deep or fast breathing with dizziness
• dry mouth
• irregular heartbeats
• irritability
• nervousness
• numbness of the feet, hands, and around the mouth
• restlessness
• shaking
• sleepiness

For healthcare professionals

Applies to olopatadine nasal: nasal spray.

General adverse events

The most frequently reported side effects were bitter taste, headache, epistaxis, pharyngolaryngeal pain, postnasal drip, cough, urinary tract infection, pyrexia, and rash.^[Ref]

Respiratory

• Very common (10% or more): Epistaxis (up to 25%), nasal ulceration (up to 10%)
• Common (1% to 10%): Pharyngolaryngeal pain, postnasal drip, cough, upper respiratory tract infection
• Uncommon (0.1% to 1%): Nasopharyngitis, throat irritation
• Postmarketing reports: Nasal discomfort, oropharyngeal pain^[Ref]

Nervous system

• Very common (10% or more): Taste bitter (up to 12.8%)
• Common (1% to 10%): Headache
• Uncommon (0.1% to 1%): Somnolence
• Frequency not reported: Hyposmia, anosmia
• Postmarketing reports: Dizziness, dysgeusia^[Ref]

Dermatologic

• Common (1% to 10%): Rash^[Ref]

Genitourinary

• Common (1% to 10%): Urinary tract infection^[Ref]

Other

• Common (1% to 10%): Pyrexia
• Uncommon (0.1% to 1%): Creatine phosphokinase elevated, fatigue, influenza^[Ref]

Gastrointestinal

• Uncommon (0.1% to 1%): Dry mouth^[Ref]

Psychiatric

• Frequency not reported: Depression/depression worsened^[Ref]

See also:

Further information

Olopatadine nasal side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer