Zofran User Reviews & Ratings (Page 5)
Zofran has an average rating of 8.0 out of 10 from a total of 273 reviews on Drugs.com. 76% of reviewers reported a positive experience, while 15% reported a negative experience.
Reviews for Zofran
- Sic...
- Taken for 1 to 6 months
- May 30, 2018
For Nausea/Vomiting "I have easily upsettable IBS (irritable bowel syndrome), and this has been a wonder medicine for me. Sometimes when I get up in the morning, I am so nauseous I cannot function. The dissolvable tablet leaves me feeling better within a minute. It has also worked when I had the stomach bug. It is working wonderfully now with a depression medicine that I just started taking that has a side effect of nausea and vomiting. I was seconds away from throwing up and quickly popped one of these in my mouth... back to normal within thirty seconds! Zofran is a lifesaver!"
- ico...
- March 3, 2009
For Nausea/Vomiting "This drug has saved my life at least once. I took it when I was pregnant and had unrelenting morning sickness that wasn't helped by any other medications. I'm now taking it again for nausea caused by severe pain (as well as the nausea caused in turn by pain medications, as I seemingly can't win on that one). But perhaps most importantly, it was the only drug that got me out of opiate withdrawal when I had the stomach flu. Without this, I would have been in the hospital because I couldn't otherwise keep anything down, and without opiate therapy, the withdrawal and the pain combined could easily have killed me. The only possible drawback is cost; even the generic would be completely out of reach for someone without insurance."
Frequently asked questions
- Anonymous
- February 9, 2014
For Nausea/Vomiting "16-year-old daughter was having headaches and was doing infusions with medications. Used Zofran for nausea. Immediately after it was injected, she had a severe allergic reaction, could not breathe, felt her throat tighten up, shortness of breath, dizziness, anxiety, shivering, and sweating. Oxygen was given, and this passed quickly within 5 minutes. Was observed in ER, and there were no other effects after that episode."
- Me ...
- Taken for less than 1 month
- November 9, 2015
For Nausea/Vomiting "Zofran is great for nausea, but watch out for the constipation. I was prescribed 15 8 mg tablets last week and have used one tablet a day since then (about 5 days now), and after waiting, walking, and drinking copious amounts of water, I am going to need to try a suppository or laxative and have my dosage of Zofran decreased to 4 mg. Great medication, it does give me nausea relief, just something to be prepared for, I know I wasn't."
Are you taking this medicine?
Your review helps others make informed decisions.- Mrs...
- May 29, 2009
For Nausea/Vomiting "This morning at about 1 a.m., I was admitted to the ER with uncontrollable vomiting. Literally, within seconds of the Zofran injection, the nausea was gone, which says a lot because I was actively vomiting when the injection was given. God bless the men and women who developed this drug. It truly is a miracle."
- Lor...
- Taken for less than 1 month
- July 16, 2019
For Nausea/Vomiting "I caught a stomach virus last winter and was vomiting repeatedly. I couldn't keep anything down. I was nauseous, dizzy, and feverish. I felt like I was on a moving boat, and I couldn't move or even think without vomiting. After I threw up bile the 2nd day, I went to the ER. I vomited in the waiting room and 3 more times in the exam room. I was given Zofran, which helped a lot. I only threw up 2 or 3 more times after that. I was diagnosed with norovirus."
- Mya...
- Taken for 2 to 5 years
- March 2, 2025
For Nausea/Vomiting "Zofran is perfect for chronic nausea. I find that it doesn’t work as well if you are going through severe episodes of nausea, but with day-to-day nausea, this medication has been a lifesaver! I am very sensitive to medication side effects and usually get every common side effect listed on a medication, but Zofran hasn’t ever really caused side effects for me. Love this medication."
- Lee...
- Taken for less than 1 month
- May 24, 2019
For Nausea/Vomiting "Wow! I went to the ER on Tuesday night, and it is now Friday, and I was given Zofran for my nausea on top of everything else I was dealing with, and this crap has made me nothing but nauseous with lots of throwing up and constipated! Not sure how long this is supposed to last, but it’s freaking annoying, and I definitely don’t see myself taking this ever again."
- Gab...
- Taken for less than 1 month
- April 20, 2017
For Nausea/Vomiting "It cost me $3 for six tablets with insurance. When I was vomiting every couple of hours for a week and was prescribed Zofran, it reduced my vomiting to one or two times a day for the next two weeks as compared to every couple of hours. It is now the third week I've been sick, and the drug works within an hour for me. There were a couple of days my prescription ran out, and I started throwing up 10 times in a day again. Highly recommend."
- Mak...
- December 31, 2017
For Gastroenteritis "I was diagnosed with GERD at 14, and whenever I feel even slightly nauseous, I suck on a Zofran, and the nausea goes away within about 2 minutes. It’s very useful, but every now and then, if I feel extremely nauseous, it doesn’t help much."
- ycn...
- June 2, 2009
For Nausea/Vomiting "I began having severe nausea and dry heaving during my pregnancy. The doctor prescribed Zofran, and within minutes the buzz of nausea was gone. Instant relief. It really took the edge off. I highly recommend Zofran."
- Anonymous
- April 10, 2009
For Nausea/Vomiting "I was given Zofran for all-day morning sickness during pregnancy. It works very well, but causes constipation, stomach cramps, and diarrhea. If I wait at least 12 or more hours between doses, the side effects are milder and the nausea is almost completely gone. Before I had this drug, I was miserable and missing work."
- Anonymous
- July 20, 2011
For Nausea/Vomiting "Have been taking this medicine for the past 17 weeks with severe hyperemesis. Have been hospitalized 7 times with dehydration. This was mainly when I had the flu on top of the morning sickness. Zofran is a really great medicine, I'm on 8 mg three times a day. Side effects include lack of appetite and constipation. But the benefits far outweigh the risk of not having it. I am able to eat and drink what I need to keep this baby growing, and although I am still not able to return to work, I am able to do day-to-day tasks. In Australia, this isn't covered by any insurance at all, and for the 8 mg, they are $120 for 10 tablets, so at 3 a day and not being able to work, it is costing us a fortune, but again, on the positive side, the baby is healthy!"
- Anonymous
- May 29, 2009
For Nausea/Vomiting "I've had severe morning sickness with both of my pregnancies. No other medication worked. I've been off work for a week, unable to get out of bed. After only two days on this drug, I can finally start living again."
- Ali...
- Taken for less than 1 month
- October 24, 2022
For Nausea/Vomiting "Went to a bad hospital with a diagnosis of heart failure. Endured three weeks there with severe nausea, no vomiting. Begged cardiologists and all staff for nausea meds. Cardiologist said, “It (nausea) has nothing to do with me (cardiologist).” Hospitalist, who had been on vacation, responded to my pleas. Zofran was magic! I swear it only took minutes to kick in. I took it for 8 to 10 days and have not needed it for the past year. I am an assertive individual, but I was sick. I should have threatened to leave the hospital, gone to the E.R., screamed, gone on a food strike (food actually eased the nausea), or done something sensational to get help. My insurance was paying thousands for me to be treated like a non-entity."
- rit...
- Taken for less than 1 month
- April 30, 2014
For Nausea/Vomiting, Postoperative "Was given Zofran for nausea in the recovery room before going to the same-day surgery unit prior to release. Ended up with nausea, dizziness, vomiting, and shivering. After the second vomiting episode, I was given Phenergan and was able to be released in another couple of hours."
- rac...
- Taken for 1 to 6 months
- August 12, 2017
For Nausea/Vomiting "I have hyperemesis gravidarum. Never have I experienced relief with Zofran, minimal, if at all. Constipation goes hand in hand with this drug, and I'd rather have N&V all day than be as constipated as I am right now. You have to weigh your pros and cons with this drug, and it's not for me."
- Joh...
- Taken for 1 to 6 months
- October 7, 2019
For Nausea/Vomiting "So, I suffer from cannabinoid hyperemesis syndrome (CHS) because of smoking pot for the last 5 years, and I have to say, what has helped is Zofran - it is really good at doing what it’s designed to do (helps nausea and vomiting) and eased the tension on my stomach. Been using it for a month every day, 2 hours before smoking whatever, i.e., concentrates or just bud. The ondansetron is miraculous and will literally save you a ton of time since when I was constantly vomiting, I couldn’t do my daily routine (going to work, hanging with friends). Man, I couldn’t even move at all, I was constantly in my bed throwing up..."
- Ood...
- Taken for 2 to 5 years
- November 30, 2015
For Nausea/Vomiting, Postoperative "I've been given Zofran pre-op and post-op for all ten surgeries, including my hysterectomy, since I always have nausea and vomiting before/after surgery. I've even gotten Zofran during ER visits for migraines, gallstones, and ovarian cyst ruptures. This is my go-to antiemetic, and I even have the ODT in my nightstand in case I ever get too nauseous. Amazing drug!"
- mom...
- September 23, 2009
For Nausea/Vomiting "I take this medicine for severe morning sickness. I would have lost my job if it weren't for this medicine! It's the best! I only have good things to say about it! The only side effects I have are light headaches, anxiety at night sometimes, not often, and constipation, but I will take any of those any day over having to be glued to the toilet and in bed for 3 or more months!"
- PLA...
- Taken for 1 to 6 months
- July 4, 2024
For Nausea/Vomiting "This medicine is a miracle drug for my IBS symptoms. I became nauseated today, for the first time in many years, which was frightening and gave me terrible anxiety. I also have an intense phobia of feeling nausea which makes my anxiety sky-rocket. I had an Rx of Zofran on hand from months ago and finally decided to take one. I swallowed it, which I kind of regretted but I was okay with swallowing it but really was unsure if it would help at all. I waited about an hour and started burping and then nausea disappeared, I became hungry and my other chronic GI symptoms virtually eliminated. I have had discomfort for decades, I may have found my miracle."
- sav...
- Taken for less than 1 month
- November 6, 2016
For Nausea/Vomiting "I was given this drug by injection in the emergency room because I had a reaction to another drug. It stopped me from vomiting. However, since immunotherapy, I have become allergic to all NSAIDs and several other drugs. One drug for a heart problem I take makes me vomit, so they gave me this drug in pill form, and well... I threw it up, and tried again, and threw it up, and this went on until I again went to the emergency room. An injection works, but the pill works only before you become nauseated. I went to another medicine, Phenergan, and that was a suppository, which worked very well."
- Anonymous
- September 24, 2008
For Nausea/Vomiting "Until my doctor gave me Zofran, I was one of the millions of women who suffered terrible morning sickness. It was so bad, in fact, that I couldn't work. The first day I took it, I became dizzy, but the vomiting stopped. The dizziness was gone by the second day. It did cause constipation, and I was hungry all the time. By the second trimester, I went off of it and found that my bowel movements returned to normal and my appetite had returned to somewhat normal. It definitely serves its purpose during the first trimester."
- mir...
- Taken for 6 months to 1 year
- October 6, 2021
For Nausea/Vomiting "I occasionally take this medication as needed for nausea that tends to come up from multiple health reasons. I have such an awful relationship with my stomach issues, and Zofran makes it go away quickly. I LOVE IT!!!!"
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Are you taking this medicine?
Your review helps others make informed decisions.More about Zofran (ondansetron)
- Check interactions
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- Drug images
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Generic availability
- Support group
- Drug class: 5HT3 receptor antagonists
- Breastfeeding
For Gastroenteritis "I'm unsure with this one. Yes, it helps the nausea a little, but I was admitted to the hospital for acute gastro - had two IV lots of this and Maxalon - lots of IV fluids - and vomited on my way out of the hospital - and every 30 minutes all night following. When I've been in the hospital and had this drug for HG (severe morning sickness), it did work, and I was asking for water and food within half an hour. I've just taken a 4 mg dissolvable and am on day 2 of the dreaded bug. Keep your fingers crossed for me xoxo."