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Zofran User Reviews & Ratings (Page 2)

Zofran has an average rating of 8.0 out of 10 from a total of 271 reviews on Drugs.com. 76% of reviewers reported a positive experience, while 15% reported a negative experience.

Reviews for Zofran

Commonly mentioned side effects
  • Hea...
  • Taken for 1 to 6 months
  • August 9, 2014

For Gastroenteritis "It hid hard and fast and took me completely by surprise when I found myself dealing with vomiting and stuff uncontrollably exiting through the other end at the very same time. A five-day prescription of Zofran from my doctor took care of everything quickly and with no side effects. Thank goodness for Zofran!"

10 / 10
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  • Bug...
  • Taken for 1 to 2 years
  • November 28, 2017

For Gastroenteritis "I can say I used to be a jealous husband because when our daughter gets the stomach bug, I sometimes got it. There is a 50/50 chance I would get it, and my wife NEVER gets it. When I found out about Zofran, it saved my life. I'm already a hypochondriac when it comes to the stomach bug, I hate it because, as a child of the '90s, there was no such pill, and I always got the dirty bug. Now I take Zofran when my daughter throws up or someone touches me with it, just in case, so I don't throw up, and it always works because I stay upset stomach-free. Just boggles my mind why docs never give it to patients, someone told me about it, that's how I knew about it."

10 / 10
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42 Report
  • RRS...
  • July 8, 2017

For Gastroenteritis "22 years on massive amounts of steroids to treat my Addison's... 22 years of vomiting most days. Many hospital stays. Severe gastroenteritis. First time trying this. It's amazing! It was prescribed by a lovely doc at my last trip to the ER. Sometimes you get lucky. My eating is broken. I'm a vibrant, beautiful 42-year-old woman, and I've been reduced to a meager 100 pounds. This helps. So far. Fingers crossed."

9 / 10
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41 Report

Frequently asked questions

  • MNC...
  • December 3, 2011

For Gastroenteritis "I went into the ER with gastroenteritis symptoms. I was given two injections of Zofran and a prescription for pills at home. It works so well and allows me to sleep really well. I have a very comfortable and calm feeling, which leads to a nice deep sleep. It works well for the nausea."

10 / 10
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62 Report
  • mik...
  • Taken for less than 1 month
  • September 13, 2016

For Nausea/Vomiting "This medicine potentially saved my life! I had no appetite. In three days, I lost 7 pounds! My wife took me to the ER, tests were ran, and the physician prescribed Zofran 4 mg, and it worked. Within ten minutes, I was eating a turkey burger with garlic oven fries. My anxiety is gone as well. I would recommend this medicine to my friends and family."

10 / 10
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  • Jas...
  • Taken for 10 years or more
  • May 12, 2021

For Nausea/Vomiting "I take Zofran only if I feel nauseated with migraine headaches. Otherwise, I take Phenergan for nausea related to severe pain. These two work very differently but work very well for my specific needs. I can't take Phenergan for migraine nausea, it doesn't work. Only Zofran works for migraine nausea. I do often have to take two, though."

7 / 10
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  • Ita...
  • Taken for less than 1 month
  • December 9, 2016

For Nausea/Vomiting "I've had central vertigo for years, but the nausea and vomiting have increased lately. My gastroenterologist prescribed Zofran 4 mg once a day. It's a miracle! I can go out and shop without vomiting in the aisles of the grocery store. I have my life back."

10 / 10
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  • J13...
  • Taken for less than 1 month
  • December 16, 2016

For Nausea/Vomiting "I was given this medication after a severe bout of anxiety and panic attacks. I lost 25 lbs in 2 weeks due to the panic and had no appetite. Of course, when you don't eat for that long, nausea can easily set in. I couldn't even move off the couch for fear of feeling extremely sick or dry heaving. I was finally given this miracle pill, and the nausea quickly went from 10 (the worst) to easily a 2 or 3 within about 45 minutes. I took it for a week as I tried to get my appetite back and anxiety under control with other meds. Highly effective. I did experience some constipation from this medication, but that could also be due to the starvation mode I was in for 2 weeks. Either way, highly recommend to anyone dealing with nausea."

10 / 10
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  • Ess...
  • Taken for 1 to 6 months
  • January 7, 2015

For Nausea/Vomiting "I am currently 25 weeks pregnant and have had bad nausea/morning sickness since week 5. This medicine has been wonderful. There are times when I still feel sick, but it's bearable, and I don't throw up. I've been taking it so long now that the sleepiness it causes doesn't affect me anymore. However, the constipation from it has been a downer."

8 / 10
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  • har...
  • January 29, 2015

For Nausea/Vomiting "I take several medications for the treatment of autoimmune disease. I had hiatal hernia surgery, so it is important I do not vomit unless absolutely necessary. Zofran works quickly to eliminate nausea and vomiting and also relaxes me."

10 / 10
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  • ash...
  • November 10, 2013

For Nausea/Vomiting "As this viral stomach bug tore through me and all my kids, it presented excruciating stomach pains. I was prescribed Zofran for myself after puking and going diarrhea for 8 hours back to back with no relief. It worked like a miracle. As this bug started on each kid, I let them puke 6 times to get the virus out. Once they were consistently dry heaving, I gave one tablet (4 mg), which is recommended for 2 to 12-year-olds. Thank God it allowed the stomach contractions to subside, and they fell asleep! However, would not use on kids 4 and under without consulting an MD."

10 / 10
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  • Ari...
  • January 25, 2017

For Gastroenteritis "This is a miracle drug! So many times, Zofran came in for the save. Saved my spouse, I, and our 7 and 5-year-old a trip to the ER when the norovirus hit us. Took it after terrible dry heaves, and within 20 minutes, I was able to sleep. This medicine also helped after my C-section when I was nauseous. When my son had hand, foot, and mouth and was uncontrollably vomiting, the doctor gave him this medicine too, within an hour, he was eating fine! This was also great for my IBS symptoms when they hit hard. 10/10!"

10 / 10
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  • ota...
  • Taken for 1 to 6 months
  • October 3, 2019

For Nausea/Vomiting "Zofran is a lifesaver! I’ve been dealing with debilitating, constant nausea for months, and some days this pill is the only thing that makes me able to eat. I’ve experienced very few side effects, if any, and am so grateful for the relief from nausea. I cannot say enough good things about Zofran or recommend it highly enough."

10 / 10
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  • Pat...
  • Taken for 1 to 6 months
  • March 4, 2019

For Nausea/Vomiting "This medication is as close to a miracle for anyone with terrible nausea as it gets. Whether you have the flu or are going through chemo, Zofran is amazing. It works on your serotonin receptors; however, it is not like an antidepressant. It targets a specific function and suddenly, almost instantly in my case, nausea is gone. I thank my lucky stars that this medication exists. For many, it is a huge difference maker."

10 / 10
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  • Dan...
  • August 19, 2019

For Nausea/Vomiting "This is the best medicine for vomiting I have ever had. I was on IV antibiotics with a lot of side effects, especially nausea, and the antibiotics could not be changed. I literally could not hold down water. I had to be on them for 3 months, and Zofran (both IV and ODT) helped me immensely. I was able to drink and even eat a little with much less nausea. People have to remember no medication may make symptoms resolve completely every time, but this comes pretty close. When I took it for regular nausea from a virus or something, it worked like 100% nausea gone. For me, there were no side effects, and again people have to remember if you're sick, some of the symptoms may not be side effects. If you're vomiting repeatedly and are dehydrated, of course, you're going to have a headache. But everyone is different, so what works for one may not have the same effects for another. But I'm a health care worker, and whoever is given Zofran usually has relief, so give it a try if your doctor says it's okay! Good luck."

9 / 10
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  • The...
  • Taken for 1 to 6 months
  • April 19, 2019

For Nausea/Vomiting "I was prescribed Zofran a few months back, I have suffered from nausea since I was 17 (I'm 36 now). This is the only drug that has ever worked for me, all the other over-the-counter meds just make the nausea worse. This makes my nausea go away within 30 mins and keeps it gone for 8 hours. I wish this had been around when I was younger."

10 / 10
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  • Sic...
  • March 21, 2016

For Nausea/Vomiting "Was very sick from antibiotics and large doses of Prednisone to help with the asthma. Couldn't hold any food down but did take enough water and Gatorade. Kept losing weight and had terrible abdominal cramps with the nausea. Finally saw another doctor after 11 days who prescribed the Zofran, and all nausea and cramps totally went away. Finally, I could start eating again! Zofran was a miracle med for me!"

10 / 10
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  • gwa...
  • Taken for less than 1 month
  • February 6, 2020

For Nausea/Vomiting, Postoperative "So I was prescribed Zofran when I got my wisdom teeth out! Worked like a charm! I also have had this huge fear of vomiting, so bad that I’ll work myself up and become so anxious that I feel like I’ll vomit. This little tablet helps a bunch!"

10 / 10
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  • icy...
  • March 13, 2008

For Nausea/Vomiting "I have had nausea and been vomiting for one year and one month. I am 16, and I have spent 90% of my life the past 1.1 years in bed sick. The last month, FINALLY, after so many medications... THIS was it. I am still being tested as no one knows what is wrong that is causing me to be so sick... BUT Zofran has made it so I can get some relief. I am grateful."

9 / 10
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59 Report
  • OLo...
  • Taken for 1 to 2 years
  • May 3, 2014

For Nausea/Vomiting "This medication works wonders for me whenever I feel sick or nauseous. The flavored tablets that disintegrate under the tongue or in the mouth are very convenient and work really quickly to relieve nausea/vomiting. The only real side effect from it that I have noticed is a slight tired feeling. I'd much rather feel a little sleepy than sick to my stomach. I really recommend this medicine if your doctor also feels that it is right for you."

10 / 10
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  • Gre...
  • Taken for 1 to 2 years
  • January 16, 2017

For Gastroenteritis "I suffer from ulcers and get acid indigestion all the time. Of course, with that, I experience nausea daily. When it gets too intense, I take a 4 mg Zofran, and within 20-30 minutes, it subsides. I thank God this medicine was created! In the beginning, I would get constipated for about 24 hours after taking a pill, but I don't have that anymore. I am thankful for this medicine because I hate nausea/vomiting."

10 / 10
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  • Nat...
  • Taken for 1 to 2 years
  • February 23, 2016

For Nausea/Vomiting "This is such an effective and helpful med. I can't tell you how many times I'd been nauseous and almost immediately got rid of it with the dissolvable version. It melts, I wait a few minutes, and then it's gone normally."

9 / 10
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  • Bel...
  • November 7, 2017

For Nausea/Vomiting "This drug has saved my sanity. I was undiagnosed with a debilitating vomiting sickness. In the hospital at least once a week via ambulance. Repetitive vomiting and could not stop. To the point where I would become unresponsive. After about a month into my undiagnosed sickness, at the emergency room, a nurse gave me a wafer of Zofran. It was a huge relief as my uncontrollable vomiting stopped within 10 minutes. I had not heard of the drug, but after finally being diagnosed, after 6 months, as having Severe Idiopathic Gastroparesis, I found my new best friend. As well as having a kidney transplant and taking a bucket full of anti-rejection meds, I was so grateful that some smart cookie out there invented this drug. Saved my life."

10 / 10
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  • Mom...
  • February 1, 2015

For Nausea/Vomiting "I'm 32 weeks, 5 days pregnant. Was admitted into maternity yesterday after throwing up every few minutes all yesterday morning. They have me fluids and Gravol, but that only made me drowsy and did nothing for the throwing up, so they decided to give me the Zofran. It started working as soon as it was in my body. It was quick and very effective!"

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • November 1, 2015

For Gastroenteritis "Like one of the reviews above. I went into the ER with gastroenteritis symptoms. Could not keep down anything, including water, due to nausea and heavy vomiting of anything. Was given an injection of Zofran and a prescription for the generic ondansetron and felt less nauseous. Allows me to eat better and to sleep."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.