Methylnaltrexone and Upset Stomach: What Users Say

• Gio...
• Taken for less than 1 month
• August 17, 2018

For Opioid-Induced Constipation "I have the most difficult time going to the restroom after taking Norco. I would stay in the restroom for hours, pushing and pushing to the point where blood would come out. I was super constipated. I went to my doctor, and she gave me 150 mg 3 times in the morning, 30 minutes before a meal. Within 20 minutes, I got horrible stomach cramps. 1 hour after waiting, I was able to poop like a normal person and a lot came out! The stool was solid, and I didn’t have to strain. After I use the restroom, the cramps are gone! It’s weird, after taking the meds, I could feel everything being broken down and everything moving down to my rectum. Sorry if that is TMI, just wanted to share an honest opinion."

• mic...
• November 18, 2014

For Constipation, Drug Induced "Prior to this product I was in a constant stage of constipation. I can recall a few times that I was so dry that it felt like I had a bad case of hemorrhoids blocking the exit. I literally believed that until I tried using Prep H on it and determined that was not a hemorrhoid. A life changer, the first time I used it I had bad stomach cramps for about 20 minutes. I raced to the bathroom and literally clogged up our system I had such a huge bowel movement. My first few uses were free samples from my pain management doctor. My prescription insurance company refused to fill my prescriptions but luckily the manufacturer sales rep coordinated an appeal for me. It changed my life, I lost 40 pounds the first 3 months I started taking them"

• Lei...
• Taken for less than 1 month
• July 16, 2021

For Opioid-Induced Constipation "I've just started taking this medication, so I can't say about the longevity, whether it'll always work the same, etc. BUT so far it works great. I take 3 of the 150 mg tablets, and in about 2 hours I have a bowel movement. I've been on morphine and dilaudid for about 12 years, and I've always had issues with painful constipation. The OTC laxatives usually cause so much pain I'd avoid them, only using Miralax every now and then. I really like Relistor because the stomach cramps are minimal compared to laxatives. The poops were still kind of hard, but maybe I just have to get the hard ones out before they start forming softer. I wish more came out, but maybe if I take it longer it will get better."