Mepolizumab User Reviews & Ratings (Page 2)

• JOD...
• August 31, 2017

For Asthma "Diagnosed borderline asthma when I was 21. Over the years, it has steadily worsened. Eight years ago, I became steroid dependent. Other than that, nothing worked. I was on literally everything I could be on, and it just wasn't enough. I was afraid my pulmonologist would give me up for a lost cause. Started Nucala in January 2017. It wasn't instant, and I actually missed two doses, April and May. When I restarted in June, it was like something clicked. I can now participate in activities with family and friends. Almost off the steroids completely. Could not be happier with these results!"

• Two...
• Taken for 1 to 2 years
• March 3, 2020

For Eosinophilic Granulomatosis with Polyangiitis "I've been on Nucala for two years. I have chronic eosinophilic pneumonia. My treatment before Nucala was 30 to 40 mg of prednisone. I'm down to 5 mg of prednisone now. 10 mg on a bad day. And zero side effects. I say amen."

• Ter...
• February 15, 2018

For Asthma "I have been on this drug for 8 years. (It was a clinical trial when I began.) I was diagnosed with HES (hypereosinophilia), and it was attacking my lungs the most: chronic pneumonia/lung infections and asthma. Despite a healthy lifestyle, I could no longer walk a flight of stairs or even half a block without being winded and dizzy. Steroid use exacerbated the infections. My doctor suggested the mepolizumab clinical trial. The dose was much higher via IV when I started, and results were apparent within a week. The main side effect was nausea, which has subsided with the lower dose. I now get monthly injections and am perfectly healthy. I work out daily and am very fit. I still have some mild asthma symptoms, but they are rare and easily controlled without prednisone. I haven’t noticed any long-term use side effects. I believe this drug saved my life. The downside is cost... Hopefully, you have a great drug plan to cover it. But I would definitely recommend trying it!"

• Duf...
• Taken for 1 to 6 months
• January 24, 2019

For Eosinophilic Granulomatosis with Polyangiitis "I am coming up to my third shot of Nucala. After the first shot, I felt normal without any allergy symptoms for the first week, but as the month went on, less comfort and more allergies came back. The second month, same thing, I felt great the first week or so, then my sinuses dried out, and I started a humidifier, which helped with that. The third week, I started getting anxiety, and it reminded me of the symptoms I had with Singulair (agitated and nervous overwhelming feelings, and then it would pass and come back at times when it was warm in the house or wherever I was). I am due for the third shot, and they claim it will improve, but I am afraid of anxiety coming back. I wish I could figure out if it’s the Nucala causing it, but it seems this is only mentioned once in a side effect on here. The shots do seem to help, but my asthma was not as serious as some described above. I am on Symbicort and Xopenex in addition to Nucala."

• Mar...
• Taken for 1 to 6 months
• February 6, 2022

For Asthma "I wanted to thank everyone for taking the time to write their experiences. In particular, one person wrote about the different asthma medications with the same effects. My asthma has been under control while on Xolair, Dupixent, forget Fasenra, and now Nucala. I’ve had muscle and joint pain with all of them, but this is my third month on Nucala, and the muscle and joint pains are worse. I’m having a real hard time with my thumbs, severe pain even when I’m not using my hands. I’ve developed a bone spur on my left thumb that is extremely painful to the touch. I’m not sure if I now have arthritis. I’m so confused about what to do next. I guess I’ll stay on Nucala until it’s obvious beyond any doubt that it is the cause of it all, and I’m unable to manage the pain. Back, neck, spine, hands, muscle spasm on my calves, etc. I forgot to mention my eosinophils were so high I was hospitalized, another reason why I was switched over to Nucala. I hope some will benefit!"

• Str...
• Taken for 1 to 6 months
• January 10, 2020

For Asthma "I have now had my second injection of Nucala. I was so happy with the results of no runny nose, chest congestion was much better. I also have a back problem and have had one hip replacement surgery and am waiting for the second one. I take maintenance medications for pain management. I started with pain so bad, my joints ached, my skin hurt, I was so tired, and got exhausted just going to town and trying to get groceries. I stay on my heating pad day and night. I am up and down frequently, my pain meds are not working well. I made an appointment to go back to the doctor and see what can be done. I liked the results of the Nucala and what it does for my breathing. Anyone have any ideas?"

• Hap...
• Taken for 1 to 2 years
• March 11, 2025

For Chronic Rhinosinusitis With Nasal Polyps "I have been on Nucala for 20 months, specifically for my sinusitis. Also had mild asthma and no sense of smell after my 3rd sinus surgery a few years ago. For me, this medication is a miracle, within a week, my sinuses were clear and asthma under control. I am now at the stage where my sinuses still clear, don't need my Symbicort for asthma, and my smell is restored. The only side effect is tiredness (but that could be age-related - 77). I will continue with Nucala, for me, it's a wonder injection and so easy once a month."

• Lil...
• July 2, 2021

For Asthma "I will definitely start reporting again as the symptoms are similar to others. It’s definitely making my asthma better, but I have side effects of lower back pain, earaches, and muscle spasms, which are real with this injection. Please report your side effects, guys, the better data they gather from the community, the better for the next person."

• Amb...
• Taken for 1 to 6 months
• October 9, 2019

For Eosinophilic Granulomatosis with Polyangiitis "A brilliant drug has helped with the lungs. I stopped wheezing after the first injection. I have now been on Nucala for six months, but I have hair loss and severe pain in my foot and all over my body, so painful 24 hours all the time. I'm not sure if it is reducing steroids slowly from 10mg to 5mg over the months or the drug, but I seem to have all the symptoms everyone is having. It has saved me from my wheezing lungs, so I will continue to see how I go."

• 500...
• Taken for less than 1 month
• January 9, 2018

For Asthma "I have been a severe asthmatic for about 45 years. I have been on a steady dose of prednisone and put on tons of weight. I worked for a while, then, when reducing the dosage, I was again in trouble. My specialist finally said, let's try Nucala, what a game changer. The second day, I felt like a new person. I could go up and down stairs without being winded. I could actually go out and enjoy myself. Our recent weather with sub-zero temps was a real test, as I usually wheeze terribly. No wheezing. The company that makes the medication is a lifesaver. Thank you so much for giving me my life back."

• Pjb...
• Taken for 1 to 6 months
• February 25, 2022

For Hypereosinophilic Syndrome "Just received my 3 shots (300 milligrams) and administered it at home. After working with my doctors. My eosinophils have gone down. But the tiredness, back pain, and headaches are horrible. Time will tell if this will be worth it. Totally off prednisone after years of taking it. Unfortunately, severe osteoporosis from the prednisone. Age 57."

• bar...
• Taken for 1 to 6 months
• September 18, 2018

For Asthma "Severe asthma since 14 years old and slowly increasing regular use of steroids, struggling to keep my peak flow over 200. Now I'm 52 and seriously thought I had just months to live. Affecting my family life every day. My eosinophil levels not very high, but doctors thought the steroids masked the true level, so they put me on Nucala. I felt a massive difference within 48 hours. Managed to reduce my steroids down to 7 mg by the 2nd shot. PF at 400 and stable. It's made a massive difference to our lives, and so I write this hoping it will help others. No side effects!"

• Bil...
• Taken for 6 months to 1 year
• May 11, 2023

For Chronic Rhinosinusitis With Nasal Polyps "Had nasal polyps and a loss of smell for several years. Started Nucala and budesonide rinses at approximately the same time. Discontinued budesonide and continued on Nucala. Polyps are better and some smell is back."

• Anonymous
• Taken for 1 to 6 months
• February 27, 2020

For Eosinophilic Granulomatosis with Polyangiitis "I have been getting the Nucala injections for about 6 months now, and for the first couple of months, I could breathe okay but developed a sinus/ear infection that caused a complete blockage in my ear. I have still been having to use my nebulizer treatments and rescue inhaler and have severe fatigue, headaches, muscle spasms, and back pain. I will not be getting any more of these injections."

• sev...
• Taken for less than 1 month
• October 27, 2017

For Asthma "I have severe asthma. Prednisone made me feel better for a little while. I had a severe allergic reaction (anaphylaxis) immediately after receiving Nucala in an infusion center in a hospital. I was transferred to the ER. I was treated and released on high doses of prednisone and Benadryl. I had anaphylaxis again (4 days later). An ambulance took me to the ER again. I was treated and given an epi pen. I continued to have an allergic reaction for weeks (high doses of prednisone and Benadryl). I wish that I hadn't been allergic to this medication."

• Anonymous
• Taken for 6 months to 1 year
• December 26, 2020

For Asthma "I have been taking Nucala for 9 months. I have severe persistent eosinophilic asthma. My asthma had a rapid onset and began about 2 years ago. I was completely healthy prior. I was using a nebulizer every 2-3 hours around the clock and on 02 at 3-5L because my airways were so tight. 10 days after the first injection, I was no longer requiring oxygen or neb treatments. Over the course of treatment, I've had a few minor setbacks, but they've been small in comparison to what I was living prior. The first couple of months, I had bad headaches and some backaches, but both resolved with ibuprofen. I get tired and flu-like at times, but a short rest usually takes care of that. I have minor skin issues, and my hair has thinned a bit, but those are things that I'm willing to deal with to have my life back. I can take my grandbaby on walks in her stroller and not be gasping for air. Nucala has been life-changing for me."

• She...
• Taken for 1 to 2 years
• January 2, 2024

For Eosinophilic Granulomatosis with Polyangiitis "It took a long time for doctors to figure out what was wrong with me--I had adult-onset asthma that was worsening along with chronic sinusitis. Then, I developed GI issues and was diagnosed with eosinophilic colitis and eosinophilic gastroenteritis. I have been on prednisone for two years. I started Nucala at 100 mg, and it helped immensely but wasn't strong enough to fully resolve everything. So, we recently increased the dosage to 300 mg due to my diagnosis of Churg-Strauss (EGPA), as that is the recommended dose. It is working quite well. My goal is to get off prednisone. I am currently taking 8-10 mg a day. I do not experience too many side effects on Nucala, except for a lot of joint pain. My arthritis has become severe, and I am soon getting surgery on my hand. Overall, Nucala is a miracle drug that has allowed me to feel so much better."

• Ver...
• Taken for 6 months to 1 year
• July 25, 2018

For Asthma "Nucala has turned my life around. I did not expect the immediate relief I experienced after the first injection. I used to get such a buildup of mucus in my lungs that I'd have to stop halfway to the bathroom and sit down to cough up a lung. I used to choke on the mucus so badly that sometimes I'd almost blackout. I effortlessly walked the half-mile home after my last injection! I went from going to the ER every 4 to 6 weeks, with 5 hospital stays in a 7-month period, to forgetting to use my nebulizer! I had to get special permission from my employer's insurance to cover this med, and it's currently up for review, so I've got my fingers crossed right now. I'm optimistic because it has been so successful. It's not currently approved by the province, but I'm hoping it will be by the time I retire, because I couldn't go back to living without it."

• Gma...
• Taken for 1 to 2 years
• October 8, 2018

For Asthma "Nucala was a life changer for me. My eosinophils were out of control, requiring three hospital stays in three months. My doctor prescribed Nucala, and for me, it was a miracle drug that gave me back my normal, active lifestyle. Unfortunately, I am not currently getting Nucala injections due to billing errors by a provider, resulting in huge co-pay amounts due from me. I am now in a post-Nucala phase until I pay the balance due. Age 70+"

• ter...
• Taken for 1 to 6 months
• April 17, 2023

For Eosinophilic Granulomatosis with Polyangiitis "Where do I start? I was fine until I took Nucala. My PSA immediately doubled, my blood pressure went up, I had debilitating back and shoulder pain, my bowels got clogged up, I was tired, and I had abdominal pain. In short, the stuff was poison to me. All these issues that came up I never had until Nucala. NONE of them. I am now off Nucala, but my back still won't heal and is very painful. Be careful what you take and what you believe about these biologics. You could not pay me to take Nucala!!"

• Dar...
• Taken for 1 to 6 months
• August 14, 2018

For Asthma "Within 2 hours of my first dose, the congestion in my lungs was gone. I still have some minor asthma symptoms, but I only have attacks the last week before an injection, and those are mild compared to before."

• Ron...
• Taken for 1 to 6 months
• January 4, 2020

For Asthma "Started off okay, but noticed the first dose caused a very bad pain in my left leg, going down to my foot, getting more and more pain as the trial goes on. Lots of other side effects coming off the trial."

• Ast...
• March 11, 2021

For Asthma "My daughter was prednisone-dependent for the past few years due to severe asthma. She was on 8 puffs of Ventolin Q2 at one point for weeks, even after a course of prednisone. That in itself should tell you how out of control it was. She has been on Nucala for 4 months now, and it has been an absolute miracle. She does not need any inhaled steroids or even Ventolin anymore. I mean ZERO. She has felt this level of relief about 2 weeks after her first injection. I cannot rave about this medication enough. But note that this is targeted for a very small subset of asthma patients. This will not help the majority of people suffering from asthma."

• Wee...
• Taken for 2 to 5 years
• February 5, 2021

For Asthma "I had an allergic reaction to Xolair and have been on Nucala for about 3 years now. I always got headaches, felt tired a day or two after I received the injection, but today was different. I got the injection Wednesday, today is Thursday, and when I got home, I wasn't feeling good, real tired, short of breath, my heart was racing, itchy throat, pain in my shoulder and up my neck where I received the shot, which I usually feel, chest is sore and my oxygen was 92-93. I went to the ER, and the doctor told me not to get the injection anymore. He did a chest x-ray and gave me breathing treatments. The injection really gave me a better quality of life, but I am scared to get it again, unsure what to do. My pulmonologist is supposed to call me back Saturday and we're supposed to talk about getting the injection again or not. With Xolair, he said I could die if I get it again, so of course, I said no, I don't want it. Has anyone else experienced this, getting Nucala?"

• Vet...
• Taken for 1 to 6 months
• August 13, 2020

For Asthma "I just had my 4th Nucala shot. I am not impressed. My severe asthma is still horrible. The shots seem to not help me. My pulmonologist said that I needed to try it through the 4th shot. I got it this morning and had 3 bad asthma attacks since then. I am going to contact my pulmonologist as soon as possible. I am not going to get any more Nucala shots. Every one of the shots did absolutely nothing for my severe asthma."