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Levothyroxine for Hashimoto's disease User Reviews

Brand names: Synthroid, Euthyrox, Tirosint, Levoxyl, Unithroid, Eltroxin, Tirosint-Sol, Thyquidity, Ermeza, Levolet, Levo-T Novothyrox Eutroxsig Evotrox …show all brand names

Levothyroxine has an average rating of 5.2 out of 10 from a total of 169 reviews for the treatment of Hashimoto's disease. 45% of reviewers reported a positive experience, while 50% reported a negative experience.

Levothyroxine rating summary

5.2/10 average rating

169 ratings from 181 user reviews.

Compare all 18 medications used in the treatment of Hashimoto's disease.

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Reviews for Levothyroxine

  • ACBar...
  • May 12, 2013

Tirosint (levothyroxine) "I was affected by the Levoxyl recall and was devastated. I had been on Levoxyl for Hashimoto's for about 3 years; it was the only thyroid med that made me feel what I thought at the time was 'good'. Looking back, I wasn't good at all...no sex drive, weight gain, swollen face, extreme anxiety. I switched to Tirosint about a month ago, and when I noticed these side effects dissipating, I was ECSTATIC but also so confused! I had no idea the Levoxyl was causing so much negativity in my life. Tirosint has NO fillers, and for that reason, all those negative side effects from Levoxyl were gone. I dropped 5 lbs almost immediately, taking me back to my post-Hashimoto's weight. Sex drive was back, anxiety decreased. Best of all, I'm just happy again!"

10 / 10
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  • Doesnt...
  • Taken for 1 to 2 years
  • January 3, 2020

Synthroid (levothyroxine) "This stuff is just awful! I’ve had my TSH go as high as 52.0 (wasn’t aware it was that out of control) and felt better than I do now on years of treatment on brand name Synthroid! Endocrinologist just doesn’t seem to agree? And now I have a whole new set of symptoms such as itchiness all over, horrible anxiety, headaches, weight gain, the list goes on and on, and nothing new has been added to my daily routine, I know it’s this medication, I hate it. Just throwing this out there for anyone else so that you know you're not crazy! Good luck!"

1 / 10
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145 Report
  • Bee
  • Taken for less than 1 month
  • September 1, 2020

Euthyrox (levothyroxine) "I was switched to Euthyrox by the pharmacist at Walmart and did not notice until I got home. I called the pharmacy and asked about the drug, and was told it was the same medication, just another brand. It is not. The first day I took it I had a migraine headache, and shortness of breath. I thought it was just me, so I went on and stayed on the medication for 2 weeks, thinking my symptoms would improve. They got worse. By the time I was 2 weeks in to taking this medication, I could barely get out of bed. It was like being in a fog all the time, with absolutely no relief. I called back and spoke to the pharmacist, this time getting a different person. He told me that my Dr could specify Synthroid and they would make sure to keep it in stock. I messaged my endocrinologist and he quickly sent in the prescription specifying Synthroid only. I am already feeling better. Please do NOT take this medication."

1 / 10
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Frequently asked questions

  • Rita
  • Taken for 6 months to 1 year
  • November 19, 2019

Tirosint (levothyroxine) "After 12 years of struggling with Synthroid and also trying NP Thyroid, which was worse, I finally found an endocrinologist that agreed that the binders in other thyroid medications were causing my Hashimoto's autoimmune reaction. Therefore, keeping my TSH not in control. I have been on Tirosint for a little over a year and have noticed a great improvement to the point of not having hypothyroid symptoms. I would suggest the makers of Tirosint should make it clear of the importance of allowing 4 hours from taking the medication and eating or taking other supplements so it does not interfere. I am forever grateful to the manufacturers of Tirosint for making this very clean thyroid medication because binders really do play a factor in Hashimoto's. I just hope I do not develop a sensitivity to glycerin."

10 / 10
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  • mls
  • Taken for less than 1 month
  • December 5, 2019

Euthyrox (levothyroxine) "This drug is causing all kinds of awful issues. My hair is falling out, I'm completely exhausted, want to sleep all day/night, can't think straight, can't make it through my work day, loose stools, headaches, cold. Increased heart palpitations. I feel exactly as I did when I wasn't taking any thing."

1 / 10
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115 Report

Are you taking this medicine?

  • LeighaV
  • Taken for 1 to 6 months
  • February 22, 2015

Tirosint (levothyroxine) "I have Hashimoto's. Tirosint has changed my life for the good! I have taken it for four months and I have felt like a human being again. I was like a zombie for 10 years on stupid Armour. Fortunately, I received a bad batch of Armour that sent me to the ER twice last October, which prompted my medication change to Tirosint. I want to let everyone know with Hashimoto's that Tirosint is truly a Godsend medication. I hope it works for you like it has for me. I had no idea how sick I was on stupid Armour. That's what I call it because Armour made me stupid. I couldn't think straight while taking it. Now with Tirosint, I'm a force to be reckoned with! I have a new job and have tons of energy! I have been reorganizing and cleaning my house."

10 / 10
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176 Report
  • Beth
  • Taken for 5 to 10 years
  • June 11, 2020

Tirosint (levothyroxine) "I have been on Tirosint for 5 year and have done fairly well on it. This past April 2020 I noticed the distributor of the drug changed but thought nothing of it. I then developed a pain in my left shoulder and also began to have an incredibly itchy rash located on my front shins. My Endo suggested it looked like an allergic reaction. We increased my dose to a higher one over five days and when I started the higher dose the rash got better but then returned. I have now switched to Synthroid and the rash has gone completely. I suspect the casing of the drug has changed with the new distributor, which doesn't make much sense. I think something has happened to the drug that they aren't telling us."

1 / 10
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More FAQ

  • Paw
  • Taken for 2 to 5 years
  • April 18, 2018

Synthroid (levothyroxine) "Had my thyroid removed 2 years ago. Was put on synthroid and have felt terrible ever since. Weight gain, joint and muscle pain, blurred vision, tremors, hair loss, constipation, irregular heart beat, stomach problems and the list goes on. Doctor tells me my numbers are fine and I should be put on an anti-depressent. Really. That's because they don't know enough about thyroid disease and keep pushing the drugs. This drug is next to poison but no one listens to us . We are held hostage to these doctors that don't care. Where do we turn to because I we are suffering. Help!!!"

1 / 10
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116 Report
  • Sally
  • Taken for 1 to 6 months
  • October 7, 2020

Tirosint (levothyroxine) "I was prescribed Tirosint-SOL in May, 2020 for Hashimoto's disease. The first month was fine with slight heart racing at night. Then on July 1, had chest pains during the night. I stopped taking Tirosint and called my doctor. At first I thought it was COVID19, and I got tested - it was negative. I stopped taking all Thyroid medicine. Had chest pains throughout July. Well, long story short, I had emergency triple bypass operation on July 27. I am 65 years old and without any other health issues. I do NOT recommend this medication. The side effects can be awful. I do not want anyone to go through this experience."

1 / 10
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76 Report
  • Lones...
  • Taken for 1 to 2 years
  • April 15, 2021

Tirosint (levothyroxine) "Oh my goodness! My endocrinologist switched me from Synthroid to Tirosint because I wasn't absorbing the Synthroid. After taking Tirosint for awhile, I started to become suicidally depressed. I'm not on many Rx, but I felt Tirosint was the culprit. I stopped taking it all together about 2.5 weeks ago. Guess what? I'm happy. (I did this on my own. Consult with doctor.) I'm not one who's into supplements, but I researched and researched and found that Selenium is supposed to help your thyroid. I've been taking Selenium since I've been off Tirosint. (Again, ask your doctor.) I'm now just taking Selenium (again, talk to doctor) and I feel great. I would NOT recommend this drug to anyone."

1 / 10
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  • Frank
  • Taken for less than 1 month
  • March 1, 2019

Tirosint (levothyroxine) "I was diagnosed with Hashimoto's a year ago and have had an underactive thyroid. I have spent years feeling very tired, irritable, depressed, no energy, no strength, no endurance, in a brain fog, crazy periods, joint pain, list goes on....overall not well. I was considered subclinical with TSH of 7 and my endocrinologist prescribed me 13mcg of Tirosint, the lowest dose. She said if it helps, great, but if not, I can stop taking it and try wait and see approach. I felt better the first day after taking the medication. I had a little more energy and was able to concentrate more than usual. I started a journal and each day I was noticing how much better I was feeling. Now it has been 4 weeks and I feel better than I have in years."

10 / 10
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88 Report
  • Jen
  • Taken for 1 to 6 months
  • June 9, 2021

Euthyrox (levothyroxine) "I've been on Levothyroxine for over 10 years and haven't had any issues. All my levels have been great. Wal-Mart pharmacy prescribed Euthyrox in place of my Levothyroxine, stating it was the same and it is NOT THE SAME!! After two months of missed periods, weight gain, brain fog, moody, depression, etc. and now my blood work has CONFIRMED my levels are all off balance for the first time in over 10 years!!! DO NOT TAKE THIS MEDICINE!! Wal-Mart, please STOP using this!! My Dr. has switched my prescription to Walgreen's and I am now back on Levothyroxine once again and throwing Euthyrox in the TRASH!! Beware it is not the same and you will be messed up!! Euthyrox should be removed and I am reporting it everywhere I can report it!!"

1 / 10
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53 Report
  • Pilat...
  • February 25, 2014

Tirosint (levothyroxine) "I have had Hashimoto's since I was in my 30s. Everything I take starts problems with my stomach, skin, hair, and nails. My doctor gave me a 2-month supply of Tirosint, and I felt 100% better. I am now switching to Tirosint and hoping that it continues to work."

10 / 10
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  • MrsDM...
  • Taken for 6 months to 1 year
  • August 22, 2014

Tirosint (levothyroxine) "Tirosint is a Godsend medication, after many side effects from generic and brand name Synthroid, it was determined that I should try this brand. I was never normal until this medication (metabolically, physically, or mentally). It just works best. I am my old self again before Hashimoto's disease."

10 / 10
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127 Report
  • Anonymous
  • March 17, 2020

Synthroid (levothyroxine) "Synthroid is terrible it fave me an exacerbation of mental health symptoms! Nervous, restless, anxiety, fatigue, constant dark thoughts and depression. My TSH dropped from .50 to .02 and still no symptoms of hyper just the same symptoms of hypo. Weight gain, tired, depression. I thought I was losing my mind! Trying to adjust psyche meds thinking that was the issue didn't work cuz it was the levo causing the problem. It's difficult to separate symptoms of mental health problems from thyroid problems because they can be similar. Got a referral from PCP to see an Endocrinologist. They switched me to Armour. Significant improvement. Levothyroxine stinks! I'd rather take no thyroid medication and suffer the consequences than take Levothyroxine. "

1 / 10
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  • LJL
  • Taken for less than 1 month
  • August 8, 2020

Euthyrox (levothyroxine) "This drug has many side effects that I am experiencing. Labored breathing - hair loss - blurred vision - fatigue - chest pain - heart skipping beats - nausea - insomnia - was taking a little oblong yellow levorthyroxin that worked great - drug store changed companies and this pill is round white."

1 / 10
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60 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 28, 2020

Tirosint (levothyroxine) "I am not the patient but have power of attorney for her. She's my mother in law and I've been caring for her medical needs for more than 15 years. She has Alzheimers disease and is now in memory care. I've been unable to visit her since the Covid started. We can talk through the mobile phone and see her through a window. She is so frail now. Losing weight. Won't eat much. Sleeps almost continually. Begs to see her family. Was changed from Levothyroxine about 3 months ago to Tirosint. Going downhill continually. 95 years old and getting good care in her memory facility (we are lucky). But this drug seems to be making her worse. Get used to it. This is what Socialized Medicine looks like."

1 / 10
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  • Anonymous
  • August 23, 2019

Tirosint (levothyroxine) "I started taking this drug Tirosint a year ago and initially felt more awake, energetic and happier. I lost some weight and was back to a comfortable maintenance weight pre-thyroid issues, but in the past few months, I have gained it all back and then some more. I honestly notice no difference in my energy levels now and in fact notice my immune system is much worse than before. I think this may all be due to the recent change in manufacturer, as all the side effects have shown up since early this year, but I’m ready to be off this drug."

3 / 10
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  • Sharo...
  • January 19, 2014

Synthroid (levothyroxine) "I've been on Synthroid for over 15 years due to Hashimoto's Disease and also partial thyroidectomy due to a nodule. For anyone who is on the medication and says they are feeling depressed, tired, etc. check into the symptoms of hypothyroidism/Hashimoto's disease as it may be that your medication is not at the right dose. My doctor considers 'normal' TSH to be between 1 and 3 while the AMA lists it as between 1 and 5. When I am at a 4, I do not feel well and have all the symptoms. DON'T just STOP taking this medication on your own as you can have severe side effects, GO back to your doctor and discuss how you feel. I cannot take the generics as they do not work for me. Only SYNTHROID for me! (I'm on 225 a day!)"

10 / 10
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99 Report
  • Nani
  • July 30, 2019

Synthroid (levothyroxine) "I was drinking Levoxyl and I was living a normal life and my doctor changed me to synthroid and it’s being a living nightmare my doctor doesn’t want to change me back to Levoxyl because he thinks it’s just my mind "

1 / 10
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  • Dore
  • Taken for 5 to 10 years
  • September 8, 2019

Synthroid (levothyroxine) "So sorry some of you are having this experience with Synthroid. I have been on this medication for 8 years now. When I started out with it, I had many of the same symptoms of all of you for about nine months. During that time I went thru 5 medication adjustments. Started out at 25 mcg , then ended up at 100mcg. Then went to taking the 100 mcg 5 times a week and cutting the pill in half two days. What worked for me is the following: -Take exactly the same time every morning -Do not eat or drink anything within the hour after that -Some medications and supplements interfere with the absorption of it. Take them 4 to 6 hours before or after. This is important because Synthroid is a narrow therapeutic dosing drug. In other words, if your dose isn't just right, you will experience all the negative side effects of both hypo and drug side effects. - If your dr isn't willing to adjust the dose for you like my dr has, find another dr."

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  • Mimi
  • Taken for 2 to 5 years
  • October 24, 2020

Euthyrox (levothyroxine) "Walmart keeps switching my thyroid medication brand. They gave me this one and I googled it. It was recalled in Europe. It is a very dangerous drug. I have contacted my physician and refuse to use it. I do not need more problems. Your pharmacy should never change your thyroid prescription brand. Medications should only be changed for a medical reason, not financial purpose."

1 / 10
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  • Akj
  • August 14, 2020

Euthyrox (levothyroxine) "Started this Euthyrox about a month ago after Walmart switched me to it. Since then I’m having daily headaches, sometimes migraines, more hair loss, and fatigue. Called Walmart and they switched me back to my previous manufacturer with no problem. This brand didn’t work for me."

3 / 10
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  • JSmith
  • January 28, 2016

Tirosint (levothyroxine) "Best thyroid drug for people that have had problems with fillers used in other thyroid medications. This drug has changed my life for the better. I have tried many different thyroid medications and was ill on all of them with many trips to the ER because horrible reactions. After 9 years feeling sick with multiple symptoms finally discovered I was allergic to the fillers used in most thyroid medicines. I will say Tirosint is stronger than other thyroid meds and I had to drop my usually dosage of 150 to 125 and have had to slowly work my way back up. I think a lot of people that are having problems with this medicine is the fact that they start on their regular dose and it is too high causes hyper symptoms."

10 / 10
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  • Penny...
  • Taken for 1 to 6 months
  • April 3, 2019

Tirosint (levothyroxine) "After nature thyroid and armour seemed to not be working I was put on tirosint by my Endo. I felt great the first week or so but since then I’ve had heart palpitations, fast heart rate, swollen legs and ankles, hair falling out and in the short 2 months I’ve been on it, I put on 13lbs. While all these symptoms were going on my TSH was 0.20, which meant I was very hyperthyroid."

1 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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