Levothyroxine Interactions
There are 239 drugs known to interact with levothyroxine, along with 5 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 219 are moderate, and 20 are minor.
- View all 239 medications that may interact with levothyroxine
- View levothyroxine alcohol/food interactions (3)
- View levothyroxine disease interactions (5)
Most frequently checked interactions
View interaction reports for levothyroxine and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Aspir 81 (aspirin)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Calcium 600 D (calcium / vitamin d)
- CoQ10 (ubiquinone)
- Crestor (rosuvastatin)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Iron Sulfate (ferrous sulfate)
- Lasix (furosemide)
- Lexapro (escitalopram)
- Lipitor (atorvastatin)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- Singulair (montelukast)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Levothyroxine alcohol/food interactions
There are 3 alcohol/food interactions with levothyroxine.
Levothyroxine disease interactions
There are 5 disease interactions with levothyroxine which include:
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
