Levothyroxine Drug Interactions
Currently displaying a list of 239 drugs known to interact with levothyroxine.
- 219 moderate drug interactions
- 20 minor drug interactions
Medications known to interact with levothyroxine
Note: Showing generic names only.
- acarbose
- acebutolol
- acetohexamide
- albiglutide
- alogliptin
- aluminum carbonate
- aluminum hydroxide
- aminophylline
- amiodarone
- amitriptyline
- amobarbital
- amoxapine
- amphetamine
- anisindione
- apalutamide
- ashwaganda
- atenolol
- calcium acetate
- calcium carbonate
- calcium citrate
- calcium glubionate
- calcium gluconate
- calcium lactate
- calcium phosphate, tribasic
- calcium saccharate
- canagliflozin
- carbamazepine
- carbonyl iron
- carteolol
- carvedilol
- chlorotrianisene
- chlorpropamide
- cholestyramine
- chromium picolinate
- cimetidine
- ciprofloxacin
- clomipramine
- colesevelam
- colestipol
- conjugated estrogens
- conjugated estrogens topical
- cortisone
- danazol
- dapagliflozin
- deflazacort
- desipramine
- dexamethasone
- dexlansoprazole
- dextroamphetamine
- dicumarol
- didanosine
- dienestrol topical
- diethylpropion
- diethylstilbestrol
- digitoxin
- digoxin
- dihydroxyaluminum sodium carbonate
- dobutamine
- dopamine
- doxepin
- doxepin topical
- dulaglutide
- empagliflozin
- ephedrine
- epinephrine
- ertugliflozin
- esmolol
- esomeprazole
- esterified estrogens
- estradiol
- estradiol topical
- estramustine
- estrone
- estropipate
- estropipate topical
- ethinyl estradiol
- exenatide
- fenfluramine
- ferric citrate
- ferric maltol
- ferrous fumarate
- ferrous gluconate
- ferrous sulfate
- fludrocortisone
- fluoxetine
- fluoxymesterone
- furosemide
- imatinib
- imipramine
- indinavir
- insulin
- insulin aspart
- insulin aspart protamine
- insulin degludec
- insulin detemir
- insulin glargine
- insulin glulisine
- insulin inhalation, rapid acting
- insulin isophane
- insulin lispro
- insulin lispro protamine
- insulin regular
- insulin zinc
- insulin zinc extended
- iron bisglycinate
- iron polysaccharide
- iron protein succinylate
- labetalol
- lansoprazole
- lanthanum carbonate
- linaclotide
- linagliptin
- liraglutide
- lisdexamfetamine
- lixisenatide
- lovastatin
- ma huang
- magaldrate
- magnesium amino acids chelate
- magnesium aspartate
- magnesium carbonate
- magnesium citrate
- magnesium gluconate
- magnesium glycinate
- magnesium hydroxide
- magnesium lactate
- magnesium malate
- magnesium oxide
- magnesium salicylate
- magnesium threonate
- mazindol
- mephentermine
- mephobarbital
- metaraminol
- metformin
- methamphetamine
- methimazole
- methylprednisolone
- methyltestosterone
- metipranolol ophthalmic
- metoprolol
- miglitol
- mixed grass pollens allergen extract
- multivitamin with iron
- multivitamin with iron and fluoride
- multivitamin with minerals
- multivitamin, prenatal
- pantoprazole
- patiromer
- peanut allergen powder
- penbutolol
- pentobarbital
- phendimetrazine
- phenobarbital
- phentermine
- phenylephrine
- phenylpropanolamine
- phenytoin
- pindolol
- pioglitazone
- polycarbophil
- pramlintide
- prednisolone
- prednisone
- primidone
- propranolol
- propylthiouracil
- protriptyline
- pseudoephedrine
- rabeprazole
- racepinephrine
- ragweed pollen allergen extract
- raloxifene
- repaglinide
- rifabutin
- rifampin
- rifapentine
- ritonavir
- rosiglitazone
- saxagliptin
- secobarbital
- semaglutide
- sertraline
- sevelamer
- simethicone
- simvastatin
- sitagliptin
- sodium iodide-i-131
- sodium polystyrene sulfonate
- sorafenib
- sotagliflozin
- sotalol
- st. john's wort
- stanozolol
- sucralfate
- sucroferric oxyhydroxide
- testolactone
- testosterone
- testosterone topical
- theophylline
- timolol
- timothy grass pollen allergen extract
- tirzepatide
- tolazamide
- tolbutamide
- trazodone
- triamcinolone
- trimipramine
- troglitazone
Levothyroxine alcohol/food interactions
There are 3 alcohol/food interactions with levothyroxine.
Levothyroxine disease interactions
There are 5 disease interactions with levothyroxine which include:
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
