Leuprolide User Reviews & Ratings (Page 2)

• Oac...
• February 3, 2014

For Prostate Cancer "Started treatment 12/2011 ended 12/2013. The PSA went down as expected for the purpose of treatment, now waiting for side effects to end, which have been: loss of libido, hot flashes especially at night or after a meal, some sweating, loss of body hair, loss of muscle mass, joint and bone pain, tiredness, difficulty to start almost any quest, weight gain, chest/man breast augmentation. Have been taking vitamin D plus calcium, glucosamine, started an exercise program that has helped with muscle buildup, and also helps with better mood, by prescription have taken 3 applications of calcium to the vein. Have had excellent support from wife, have trust my Doctors and first of all God my father."

• Tom...
• Taken for 1 to 6 months
• May 25, 2019

For Prostate Cancer "Been on Eligard for two months, and it has taken all the joy out of life. There will be no second injection. My life expectancy is better with cancer than with Eligard, and I'm fighting such dark thoughts almost every day, afraid I'm going to hurt someone. The mood swings are unpredictable and scary. Sex is becoming near impossible all the time."

• WWI...
• Taken for 6 months to 1 year
• February 18, 2015

For Prostate Cancer "Have been getting monthly Lupron 7.5 mg injections since July 2014 (just had my 8th injection). No hot flashes; some mood swings and I recently started having arm and leg cramps a few times a week. Taking Casodex 50 mg daily as well, so it's hard to know which to blame. PSA was 205 when I started these meds and is now 0.03. I believe the complete lack of hot flashes may be due to receiving the monthly vs 3 or 6-month injection dose. I hope this information helps others."

• Lup...
• Taken for 1 to 6 months
• February 19, 2019

For Uterine Fibroids "I wanted to write a review for other women who are thinking about getting this injection. I read a lot of horror stories online, so I was pretty nervous. I got the 3-month injection to try and shrink my large fibroids. The upshot is, it wasn't that bad, but my fibroids didn't shrink; however, it stopped my periods. Preventing the excessive bleeding is good for health prior to a hysterectomy. But it's expensive, and insurance will make you jump through bureaucratic hoops to get it. After getting the shot, I felt kind of weird. Then I had one last awful period blowout a few days later. Since then, no periods. Menopause symptoms included hot flashes, brain fog, mild acne, some moodiness, and irritability. However, I think a lot of this can be worked around with good nutrition, exercise, breathable clothing, and meditation."

• 65...
• Taken for 6 months to 1 year
• November 22, 2015

For Prostate Cancer "I am experiencing the following side effects: Breast enlargement, reduction of size of testicles, complete ED, multiple hot flashes hourly, and a mental fog that prevents clear thinking. These were all expected side effects and came as no surprise. Additional unexpected side effects include: rapid pulse rate, elevated BP, breathlessness, short-term memory loss, extreme and uncontrollable emotional outbursts (uncontrollable crying over minimally emotional issues), and sleep deprivation (1-2 hours total sleep which could account for the emotional issues). Of additional concern are anecdotal statements by others claiming no reduction of any side effects even after years of removal from follow-up injections of Lupron. My concern is great enough to request suspension of this drug, even at the cost of an elevated PSA with a corresponding resurgence of the cancer. I know there are additional drugs I can take to counteract some of these side effects, but I would rather not complicate the situation with even more medication. My PSA stands at 0.3 as of this writing, and I would withdraw my request were it to increase to 4.0, however continued living with this nightmare drug is not my idea of life."

• Jer...
• Taken for 6 months to 1 year
• April 30, 2023

For Prostate Cancer "I have had my second dose of Eligard 45 mg, 6 months apart. Radiology convinced me I should do this to prevent the recurrence of cancer. I had a Grade 4, contained to the prostate. Had 28 radiation treatments. My PSA now is at zero. I have told the doctors I 'will not' take any more hormone injections. My life has been ruined. I am turning 76, but I have been an active walker, biker, lifted weights, etc., all my life. Now I have intense bone pain all over my body, my muscles are half what they were, and I have hot flashes all day and night. I force myself to exercise, but life is now hell. I get depressed and emotional. Wish I had never taken the first injection. Not sure if my body will ever recover. The doctors need to educate their patients with proper data and let them make a choice."

• Rus...
• Taken for 2 to 5 years
• February 6, 2015

For Prostate Cancer "Prostate removed - huge 350 cc - Gleason 7, PSA 15, radiation for 8 weeks, Lupron every 3 months for one year, every 6 months for the next year and a half. PSA has been less than 0.01 since initial radiation. Weakness, memory problems, and hot flashes but no cancer. Treatment is worth the side effects. I feel very lucky."

• Anonymous
• June 11, 2012

For Prostate Cancer "My cancerous prostate was removed when I was 65, 6 years ago. I receive a 22.5 mg Lupron injection about every 3 months. My PSA decreases each time from about 2 to undetectable. The injection area is sore for 2-3 days after each injection. I have perhaps a dozen relatively minor hot flashes daily. I take 4 venlafaxine HCl 75 mg tablets daily to curtail hot flashes."

• mik...
• September 17, 2009

For Prostate Cancer "I've been on Lupron (after prostate surgery) for a period of 7-1/2 years. I am also on 50mg Casodex. The side effects are minor (hot sweats, decreased energy). Injection sites were moved after 6 years from buttocks to shoulders due to lower back pain. I hope this gives hope to patients about to begin this regimen."

• lup...
• Taken for 1 to 6 months
• August 25, 2018

For Prostate Cancer "I had prostate cancer 10 years ago, so they say. 43 treatments of radiation, and the PSA is gone. Now, 67 years old, and my PSA went up to 8.5, 10 years later, and my doctor wants to do the Lupron shot. First one, 2 years, a big one, 45 mg. It almost killed me - I had never been so sick. Now, 2 and a half years later, my PSA was 13, so I told the doc I would try a smaller dose, so I did 7.5 a year ago and another 7.5 last week. My PSA is 3.2, but still, I said I should take it. Let me tell you, men, I WILL NEVER TAKE ANOTHER LUPRON SHOT AS LONG AS I LIVE. The side effects you read about are true: blood pressure problems, diabetes. I'm never having a Lupron shot ever again."

• Ber...
• Taken for less than 1 month
• May 7, 2014

For Uterine Fibroids "I must admit, after reading the comments, I was real scared, but I told myself everyone's body reacts differently. May 6, 2014, I took my first shot. So far, I am feeling great. I was a bit drained before I took the shot, woke up feeling energetic."

• Wor...
• Taken for 1 to 6 months
• March 19, 2018

For Uterine Fibroids "I am 52 (5'8", 155 lbs) with a large (13 cm) intramural fibroid (fibroid within the muscle wall of the uterus). In case I had any adverse reaction to Lupron, I decided to take the low dose injection (1 time a month) instead of the single high dose that lasts three months. I felt pretty okay with Lupron, other than a dull headache that lingered on for two months (I only had two injections). The actual fibroid did not shrink much after two months (from 13 to 11 cm), but the surgeon said it made the fibroid softer. I had a laparoscopic hysterectomy with success. I was 90% recovered after five days."

• Mr ...
• October 26, 2016

For Prostate Cancer "Diagnosed with stage 4 PC in my right hip. PSA for years was between 2.0 to 3.5. Went from 3.5 to 29 in one year! I encourage all with a PSA of over 3.0 to get a bone density test! Started Lupron 30-day shot on July 5th, 2016. First 3 months went from 29 to 3, so heading in the right direction. Bone pain reduced after the first shot by more than 75%. Hot flashes around the clock, roughly 10 to 12 a day with an intensity level of about a 5 or 6. Very annoying but tolerable. Miscellaneous aches and pains in joints and muscles. Occasional fogginess and definitely wake up too much to pee. I'm trying Flomax now, I hope to see some improvement. Fatigue is real! I can't tell if this is harder on my family than me! So far, so good. God bless to ALL!"

• Ano...
• Taken for 2 to 5 years
• June 28, 2016

For Prostate Cancer "I am the wife of a man currently taking Eligard. I have to say it has worked to keep the prostate cancer from spreading, which is absolutely wonderful. However, it has caused a lot of other problems that have affected both of us. He has absolutely no sexual desire, he has developed what appears to be breasts, his penis has become inverted, and his testicles have decreased in size. His muscle mass has decreased as well, and the weight gain is mostly in his belly. I can only hope that he will regain his manhood if and when he is taken off this medication."

• Mik...
• October 18, 2011

For Prostate Cancer "Got a shot of it on Friday, some soreness on Saturday; but saw immediate results of reduced urgency to void every hour, sometimes 4-5 times per hour, depending on consumption of liquid. Some sensitivity to the right side of the groin and scrotum. Seemed like it might be some blockage in semen tubing or possibly the medication impacting the two lymph nodes that showed some cancer invasion. Now it is Tuesday evening, and the sensitivity on the right side of the groin is minimal. It is really amazing how fast the medication impacted the symptoms. I got a 3-month shot and expect to do a blood draw in 6 weeks to evaluate the impact on the PSA levels. So far, so good."

• Anonymous
• April 18, 2011

For Prostate Cancer "Second injection started night and day sweats. This has increased to every 2-3 hrs during the day - less frequency at night. Dropped my PSA from 30 to 0.07 post-prostate removal. Time on medication: 6 months."

• Scr...
• Taken for 6 months to 1 year
• October 13, 2020

For Prostate Cancer "Husband got an Eligard shot to minimize the size of the prostate to prepare for radiation with a 6-month follow-up. When he returned, the cancer had spread to his bones, and PSA went from 32 to 182 in those 6 months with no additional PSA tests given. The shot was ineffective, and we were not informed that it could metastasize to other body parts, giving us a choice of a different treatment that would not limit his life.... Demand monthly PSAs!!!"

• Lin...
• Taken for less than 1 month
• September 30, 2018

For Endometriosis "I’m a 24-year-old female who’s suffered from terrible endometriosis pain; my periods left me crumpled up on the ground, moaning in pain to the point that I seriously wished I were dead. I am not exaggerating in the slightest. Sometimes I’d get really dizzy and hear an intense buzzing in my ears right before I almost passed out. The pain was unbearable; I often had to miss school and work because of my period. I recently underwent surgery and was recommended Lupron. I read horrible reviews about it for weeks leading up to my doctor appointment and was terrified to try it, but so far I haven’t had any problems other than hot flashes (and that’s MUCH preferable to the agonizing pain I used to be in). Of course, it’s only been a few months since I got the injection, so we’ll see...but so far it’s been great! Don’t let the reviews scare you; if you’re in good health like I am, you probably won’t experience serious complications or side effects. Hope this helps!"

• Amb...
• November 2, 2015

For Endometriosis "I have been taking this for 6 months now, about to start my 7th, and I love it! I will say the first month or so, I was really wondering what I had gotten myself into. But now, I am so glad I did it. I take the 1-a-month, not the 3-month shot. I haven't had a period in 5 months, and I haven't cramped in 5 months. I was having hot flashes before I started taking this, and I will say that at times they are way worse, but I would much rather deal with hot flashes than be huddled over in my bed because the cramps are so bad that I can't even function. I do understand that some people have bad experiences with things, and some people don't. It is all up to your body. Everyone's body is different. I hope seeing a good review like this will help."

• WWI...
• Taken for less than 1 month
• August 7, 2014

For Prostate Cancer "Had my first injection of Lupron 7.5 mg in July, second injection at the same dosage is set for August 21. So far no hot flashes or side effects. Have been taking Casodex simultaneously (30-day supply) which will end shortly. Only side effect from that initially was fatigue, which resolved after 5 days. Decided to insist on 1-month Lupron injections instead of a 3-6 month extended dose as PC support group participants on the once-a-month dose had far fewer side effects. I'm sticking to my guns on this one, MD tried to give me a 6-month dose right off the bat. I'm switching MDs and glad I did it this way. Hope this helps others."

• Inl...
• December 30, 2011

For Prostate Cancer "Recently received my first Lupron injection. Within one week my PSA dropped from 69.7 to 11. I have not noticed any severe side effects as of today. I am also starting Alendronate Sodium tablet for healthier bones."

• Jen...
• Taken for 1 to 6 months
• February 13, 2020

For Endometriosis "I feel like I’m one of the few people who has had a positive experience on the medicine Lupron. I’ve been pain-free from my endometriosis for 3 months, now on my third dose. After my first dose, I had some joint pain and severe hot flashes for a couple of weeks, but those symptoms lessened as time went on. My mood has changed for the better while on this medicine, I no longer have pain from the endometriosis, and my only symptom from this medicine is minor hot flashes! I can’t believe it. This medicine has been a blessing."

• Len...
• July 13, 2016

For Prostate Cancer "Eight months into Lupron plus Casodex, and I am refusing the next three-month shot. PSA went from 5.7 to 0.2 to 0.1, and I am just finishing up nine weeks of radiation. GL scores were mostly 9's, but no metastatic found. To say a less common side effect is loss of libido is just plain BS. About a month after the first shot, I was done with sex. The doctor said once the testosterone is gone, that's normal. Little aches and pains linger, my testicles shrink, I lost all hair under my arms and it's slow-growing elsewhere. Sometimes I seem to be in a fog mentally. Hot flashes like you wouldn't believe until they offered me other meds, which help somewhat. I put on five pounds of blubber below the belly. Lack of energy as well. It works, but I think doctors keep you on it too long for stage 1 or 2 cancers."

• ble...
• Taken for 1 to 6 months
• December 18, 2012

For Prostate Cancer "I got this shot about two years ago. I was told by the urologist that it was a one-month shot. I had the shot because we wanted some time to research and decide what treatment would be best. Found out later that it was a 3-month shot! Suffered severe side effects! PSA dropped from 13 to 7, but the side effects were NOT worth it! Hot flashes, with some of them causing me to nearly pass out, were often (20 a day), memory problems, muscle/joint pain, and on and on! Once, while teaching, I suddenly didn't know where I was or what I was doing! After radiation, I was recently put on Trelstar on a MONTHLY basis, nearly the same side effects but NOT the really bad ones!"

• Bil...
• Taken for 1 to 2 years
• November 6, 2016

For Prostate Cancer "I must say if I only knew what this medication was going to do to me, I would have never taken it. At the age of 61, this medication has destroyed my life. After each injection, it caused deeper and deeper depression. What at one time brought joy to my life is gone. There is no sense of any type of sexuality at all. Nothing brings joy to one's life. After each shot, it just makes it worse. The hot flashes are so severe I will have to change my work shirt a couple of times a day. I will soak a shirt within minutes. One has to remember that the Eligard will get rid of all your hormones. We are not made to run that way and there is no support that will help you deal with that or tell you what to expect. You are no longer male but not female either."