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Inclisiran User Reviews & Ratings (Page 4)

Brand names: Leqvio

Inclisiran has an average rating of 7.1 out of 10 from a total of 107 reviews on Drugs.com. 46% of reviewers reported a positive experience, while 7% reported a negative experience.

Reviews for Inclisiran

Commonly mentioned side effects
  • Div...
  • Taken for 1 to 6 months
  • March 15, 2023

Inclisiran for High Cholesterol "I am having the most severe muscle pain and tight muscles I have ever had since I have been on Leqvio. Has anyone else had this?"

4 / 10
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132 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 8, 2023

Inclisiran for High Cholesterol "Side effects, hives, itching, pain with urination, headaches, dizziness, blurred vision, and sweating."

1 / 10
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72 Report
  • Sus...
  • Taken for 1 to 6 months
  • May 25, 2023

Inclisiran for High Cholesterol, Familial Heterozygous "Have had significant hair loss. Pain in legs and knee joints. Both knees have cartilage and meniscus damage, with no previous history of knee injury or knee-related issues."

4 / 10
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50 Report

Frequently asked questions

  • Eli...
  • Taken for 6 months to 1 year
  • April 3, 2024

Inclisiran for High Cholesterol "About a month after Leqvio shot, I get heartburn, nausea, belly cramps, fatigue. Numbers are good, but not liking the side effects. Anyone else having similar issues?"

7 / 10
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30 Report
  • San...
  • September 4, 2024

Inclisiran for High Cholesterol "Two weeks after the first injection, I developed pain in my hips, lower back, ankles, feet, hands, including toes and fingers, burning with urination, burning in my eyes, fatigue, and headaches."

2 / 10
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18 Report

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  • rog...
  • Taken for 6 months to 1 year
  • May 19, 2024

Inclisiran for High Cholesterol "Not sure if this is related to Leqvio or not, however, since beginning the Leqvio regimen I have experienced an increased level of muscle and joint pain and reduced mobility."

6 / 10
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21 Report
  • Eli...
  • Taken for 1 to 2 years
  • May 22, 2024

Inclisiran for High Cholesterol "Had high hopes, but too many gastrointestinal side effects. Also muscle pain and stiffness. Lowers cholesterol but 2 months after the shot, I still have side effects."

7 / 10
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18 Report

More FAQ

  • Dav...
  • Taken for 1 to 6 months
  • August 6, 2023

Inclisiran for High Cholesterol "Leqvio works very well to lower the LDL cholesterol, but I am having substantial weakness in my legs. No other side effects. Would hope there is some way to eliminate the weakness."

10 / 10
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25 Report
  • L h...
  • Taken for 6 months to 1 year
  • May 28, 2024

Inclisiran for High Cholesterol "It has lowered my LDL. However, I have noticed that my skin started to wrinkle a great deal after my third shot. Has anyone else experienced this symptom? It is my only adverse reaction."

8 / 10
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15 Report
  • Mlh...
  • Taken for 1 to 6 months
  • March 12, 2023

Inclisiran for High Cholesterol, Familial Heterozygous "I had a terrible reaction to Repatha, so I requested Leqvio. I had my first dose 3 months ago, and I haven't had any problems with it at all. I have my second dose scheduled in another 2 weeks."

10 / 10
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25 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • May 6, 2023

Inclisiran for High Cholesterol "Took first dose in October 2022. Bad cholesterol was 105. Second dose in January. Bad cholesterol was 45 in February. Cardiologist was amazed!! Feel much better this summer."

10 / 10
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17 Report
  • Mor...
  • Taken for 1 to 6 months
  • October 9, 2024

For High Cholesterol "Hair loss second month. I have fine hair, can’t afford to lose anymore."

6 / 10
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6 Report
  • Anonymous
  • Taken for 1 to 6 months
  • January 13, 2025

Inclisiran for High Cholesterol "After my first injection, all seemed fine, but two weeks in I have arthralgias of the fingers and severe constipation, dry lips."

4 / 10
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4 Report
  • Jay...
  • Taken for 1 to 6 months
  • September 5, 2024

Inclisiran for High Cholesterol "Painful joints when moving around after sitting. Troublesome cough. Feeling nauseous frequently, especially in the morning before breakfast."

7 / 10
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5 Report
  • Ano...
  • Taken for 6 months to 1 year
  • May 30, 2025

For High Cholesterol, Familial Heterozygous "Itchy erythema: 10 cm in diameter for over 10 days and sore joints."

8 / 10
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1 Report
  • Mar...
  • Taken for 6 months to 1 year
  • April 18, 2024

Inclisiran for High Cholesterol "Leqvio helped me lower my cholesterol levels significantly. I cannot take statins because of the bone and muscle pain. However, I have bone and muscle pain even with taking Leqvio."

9 / 10
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6 Report
  • Fre...
  • Taken for 2 to 5 years
  • June 29, 2024

Inclisiran for High Cholesterol, Familial Heterozygous "Have just received my 4th injection. Further to my May '23 post. Cholesterol has remained low, slight muscle pain continues, believe it has contributed to some hair loss. Feel overall more energetic."

9 / 10
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5 Report
  • Tho...
  • Taken for 2 to 5 years
  • January 1, 2024

Inclisiran for High Cholesterol "Worked for me, been taking it for a couple of years."

10 / 10
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5 Report
  • Mfs...
  • Taken for 6 months to 1 year
  • March 29, 2025

For High Cholesterol "So far, so good, nearly 12 months' use in conjunction with pravastatin."

8 / 10
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1 Report
  • Anonymous
  • April 15, 2024

Inclisiran for High Cholesterol "Lowest numbers I have ever had. Not aware of any side effects."

10 / 10
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3 Report
  • Ifr...
  • Taken for 1 to 2 years
  • February 23, 2025

Inclisiran for High Cholesterol, Familial Heterozygous "Reduced LDL, now listed as too low. UTIs, leg pain, hand nodules. Have to wait out the 6-month dosage to eliminate it."

5 / 10
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1 Report
  • jac...
  • Taken for 1 to 6 months
  • February 29, 2024

Inclisiran for High Cholesterol "Massive drop in LDLs with Leqvio. Medication was prescribed by my cardiologist, and Medicare with Supplementals paid for its EXPENSIVE costs."

10 / 10
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2 Report
  • she...
  • Taken for 1 to 6 months
  • April 12, 2024

Inclisiran for High Cholesterol, Familial Heterozygous "Have felt better, not had blood work yet to check levels."

10 / 10
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1 Report
  • lee...
  • Taken for less than 1 month
  • November 27, 2023

For High Cholesterol "No problems at all. Took the shot on 9/27/2023. No side effects."

10 / 10
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0 Report
  • Ano...
  • Taken for 1 to 2 years
  • June 11, 2025

Inclisiran for High Cholesterol "I’ve been getting Leqvio shots for a year and a half now. I haven’t gotten any side effects so far. My cholesterol levels have dropped quite a bit. I’m satisfied with the results."

10 / 10
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0 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.