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Inclisiran and Itching: What Users Say

Brand names: Leqvio

Itching: mentioned by 5 users (4.4%)

Based on user experiences from 114 Inclisiran reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

muscle pain 12.3%
pain 11.4%
joint pain 10.5%
burning 7.0%
fatigue 7.0%
cramps 5.3%
headaches 5.3%
itching 4.4%
muscle aches 4.4%
nausea 4.4%

Reviews for Inclisiran

Commonly mentioned side effects
  • Jos...
  • Taken for less than 1 month
  • May 15, 2024

Inclisiran for High Cholesterol "After about 4 days: nose bleed, sinusitis, sore lips and tongue. Feeling of exhaustion for a month. After 2 months, developed eczema and psoriasis on shins, and after a further week extremely itchy spots on trunk, arms, and legs. After month 1, cholesterol had reduced from 5.4 to 4.5."

7 / 10
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31 Report
  • Joh...
  • Taken for 1 to 6 months
  • May 6, 2023

Inclisiran for High Cholesterol, Familial Heterozygous "I am a 74-year-old male. Just had the second dose of Leqvio. (I had to stop Praluent after two dosages due to extreme itching.) LDL has reduced by 50% after the first dosage 3 months ago. I have experienced slight muscle discomfort, but nothing major. Highly recommend treatment, but it is expensive."

9 / 10
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30 Report
  • Let...
  • Taken for 6 months to 1 year
  • January 30, 2025

Inclisiran for High Cholesterol, Familial Heterozygous "Initial lowered cholesterol, but later injections, severe rash appeared many days later, size of lemon at injection site. Very sore, red, and itchy, lasting many weeks. Antihistamines helped, as well as cold compression."

6 / 10
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3 Report

Frequently asked questions

  • Ano...
  • Taken for 5 to 10 years
  • July 13, 2025

"I have been on the study for about five years, having an injection every six months. I have not felt any discomfort apart from the last year when I have been diagnosed with diverticulitis and random itching, mainly on the torso. I do not know if I am on the placebo, but will ask at the end of the program."

8 / 10
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0 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 8, 2023

Inclisiran for High Cholesterol "Side effects, hives, itching, pain with urination, headaches, dizziness, blurred vision, and sweating."

1 / 10
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73 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.