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Inclisiran and Nausea: What Users Say

Brand names: Leqvio

Nausea: mentioned by 5 users (4.4%)

Based on user experiences from 114 Inclisiran reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

muscle pain 12.3%
pain 11.4%
joint pain 10.5%
burning 7.0%
fatigue 7.0%
cramps 5.3%
headaches 5.3%
itching 4.4%
muscle aches 4.4%
nausea 4.4%

Reviews for Inclisiran

Commonly mentioned side effects
  • K-T...
  • Taken for 1 to 6 months
  • August 15, 2024

Inclisiran for High Cholesterol "Just had 2nd injection…side effects abound (headache, nausea, muscle weakness and pain, low backache, constipation, ridiculous levels of fatigue, and much more) and never fully dissipated after 1st injection…fully started up again with this injection…all are annoying and affect quality of life…arthritis pain in hands and feet, and cramping in feet, legs, hands are among the worst along with the continual migraine. The medication definitely dramatically lowered my LDL…just not sure I want to continue."

9 / 10
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82 Report
  • Jay...
  • Taken for 1 to 6 months
  • September 5, 2024

Inclisiran for High Cholesterol "Painful joints when moving around after sitting. Troublesome cough. Feeling nauseous frequently, especially in the morning before breakfast. Night cramps every night disturbing sleep, and therefore causing tiredness the next day. Extreme fatigue during the day needing an afternoon nap."

6 / 10
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22 Report
  • Nai...
  • Taken for 1 to 6 months
  • June 7, 2023

For High Cholesterol, Familial Heterozygous "I am experiencing severe muscle and joint pain, nausea, headache, sweating, palmar erythema, hives, the soles of my feet are burning hot, painful urination, and abdominal pain! Inclisiran damaged my liver! Are the side effects ever gonna go away? I was stupid to agree to have this poison. I'm really scared."

1 / 10
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31 Report

Frequently asked questions

  • Hal...
  • Taken for 1 to 2 years
  • July 30, 2025

Inclisiran for High Cholesterol "WEEK 1 1. Post-administration [SQ Abdominal Area] Pain at the injection site. 2. Moderate to severe tiredness [Lethargy] lasting 4 days. 3. Irregular heart rhythms [Atrial Tachycardia] [Sinus Tachycardia]. 4. Generalized muscle aches and pains [Specifically in Legs]. 1. Increased vertigo coupled with moderate headaches [Frontal headaches]. WEEK 2 2. Mild intractable nausea requiring OTC antiemetic drugs. 3. Painful muscle cramping [Specifically in Legs & Feet, Toes]. 4. Out of control blood glucose levels [Requiring introduction of Insulin]. WEEK 7 1. Urinary urgency [Specifically at night]. 2. Painful hands, burning sensations in tendons of digits [Fingers]. 3. Cough with constant production of thick mucus [Bronchitis]. 4. Weakness in lower extremity [Legs]. WEEK 12 1. Frequent onsets of sudden severe vertigo and leg weakness. 2. Continued out of control blood glucose levels [Requiring higher doses of Insulin]."

5 / 10
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0 Report
  • Jay...
  • Taken for 1 to 6 months
  • September 5, 2024

Inclisiran for High Cholesterol "Painful joints when moving around after sitting. Troublesome cough. Feeling nauseous frequently, especially in the morning before breakfast."

7 / 10
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5 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.