Hysingla ER User Reviews & Ratings (Page 4)

• Anonymous
• September 21, 2020

For Pain "Was on Vicodin for many years before switching to Hysingla. I take 30 mg a day and four 10 mg per day. Didn’t have my Hysingla for one month due to a manufacturing issue, and it was a nightmare. I love the 24-hour pain control of the Hysingla!"

• Inj...
• Taken for 1 to 6 months
• April 18, 2017

For Pain "This is an update to my posting late Jan. Now, after 4 months of titration, I'm at 40 mg. But disappointed. I could sleep 12 hours each night if allowed to, constantly tired. And taking a new Hysingla pill every 15-18 hours for bleed-through pain. Definitely missing my old four times a day Percs, but I'd be doubling up on those too, I'm sure. So, Dr. says live with it. Pain level at 2. But never any better. And that's disappointing. Dr. won't go higher."

• Bub...
• Taken for 1 to 6 months
• January 28, 2023

For Pain "At first, this was marginally effective, but only at double the prescribed dosage (20 mg). It stopped most of the pain for about 16 hours but took several hours to take effect. After being on this for about a month, it's doing almost nothing for the areas that are having chronic pain, and now is causing pain and stiffness in my hands, neck, and back, areas where I wasn't having any pain prior to this. Strange thing is, regular hydrocodone works pretty well, with none of the same side effects. Likely whatever is different with the formulation to increase the length of effect is what is causing the increased pain and stiffness. Really disappointing as I was hoping this would work."

• Sue...
• Taken for less than 1 month
• April 29, 2023

For Pain "My 76-year-old husband was prescribed Hysingla ER last year and ended up in the ER with serotonin syndrome after taking one pill. He was admitted to the ER almost comatose. He was taking other serotonin-loaded medications and NEVER should have been prescribed this. After a week, he was put into a rehab facility. He contracted COVID and died."

• Hmp...
• Taken for 1 to 6 months
• November 18, 2017

For Pain "This medicine is a joke. They want to take you off Percocet and hydrocodone and put you on this medicine, which is supposed to be longer acting. But I’d rather take six Percocet 10 mg a day than one of these. They had me on 40 mg for four weeks, it didn’t help with my pain whatsoever."

• imb...
• Taken for 1 to 6 months
• April 14, 2017

For Pain "Update. Took Hysingla 30 mg for 1 month, with 10/325 Norco. Hysingla A.M. gave severe headaches and nausea. I switched to 10 pm and now I wake up less stiff, but can't tell the difference during the day. I still do Norco every 4 hours. I had a caudal epidural injection today. It was supposed to be my follow-up appointment too, but never had a chance to speak to the PA about the new Hysingla. She mentioned last month if I tolerated it well, she may increase the dose to 40 mg. I've tried to research 80 mg per day total, but can't find the answer, I know that's what she'll look at. I'd like to call and ask about getting Hysingla corrected to 40 mg for this month instead. I hate to waste money for no improvements again. I won't know if the caudal worked for a few days yet, all other injections only lasted 1-2 weeks. Answers??"

• Gsa...
• Taken for 1 to 6 months
• February 1, 2017

For Pain "My medical internist prescribed this medication for me. I've been taking it for three months or 2.5 months. I've noticed the medication doesn't work that much, and I would have to take Norco 10/300 for breakthrough pain because I could just stop taking this medication cold turkey, I would have serious withdrawals that could be deadly. So, he started me on Norco 10/300, 1 every four hours to prevent withdrawals. I noticed my weight had started to increase - I was 128 lbs, 5'4" and noticed my weight has increased to 140 lbs, and it's all butt and thighs. I'm so insecure about my body, I don't feel right. My husband told me it shouldn't matter just as long as he loves and likes my body. I love him so much, but there's me on the inside that yells out."

• The...
• November 30, 2017

For Pain "I have had chronic pain since 2002. I have reflex sympathetic dystrophy (RSD) in low back, both legs below the knee, both feet. Long story short, I have been on pretty much every pain med there is. Had over 200 nerve blocks. Had nerve endings burned off. PT, you name it. Now I have a medicine dosing machine inside my abdomen with a cath that runs directly into my spinal cord. I tried this Hysingla, it's worked great. I'm surprised so many people have not had relief from it. But if I didn't have the pump implant, I'm pretty sure I would be on the highest dose they make."

• Ken...
• Taken for 2 to 5 years
• February 9, 2018

For Pain "Great for pain management. I had 28 years on opioids after 12 surgeries. Total disagreement with Florida wanting to regulate it to a 3-7 day supply when Florida allowed 'pill mills' to operate for years. Lost kin to Florida looking the other way, now want lawsuits against manufacturers? Absurd thinking, China is killing people by shipping opioids via USPS, buyers unaware of the potency of drugs such as fentanyl, oxy, etc., and Florida rehabs are milking my tax dollars with commercials showing resort living rehabs. Ignorance is bliss."

• Anonymous
• November 4, 2017

For Pain "Had great analgesia with OPANA 40 mg q 12 hrs. gradually upward over a three-year period. But not getting any pain relief (bilateral diabetic peripheral neuropathy) from 30 mg ER HYSINGLA for the last two weeks. Do I need to titrate higher quicker?"

• Lil...
• Taken for less than 1 month
• July 29, 2023

For Pain "I started to take Hysingla ER last night. This morning my throat was bothering me and it felt like it was closing up. This evening I retook the medication, two hours later I'm breaking out into a rash. Has anyone had this experience happen to them? Does anyone know if this medication is derived from penicillin? By the way, it has done nothing for me pain-wise. They said this would last all day and 4-6 hours later I'm already taking morphine and/or Norco. It's so frustrating."

• Dia...
• March 3, 2018

For Pain "Dr. started me on hydrocodone 20, and after being on Norco 7.5 for almost a year, the hyd 20 is a blessing. I take 1 tablet in the morning, and my pain is manageable all day @ 2-3 level. While on Norco 7.5 mg, I suffered from 7-9 daily! Physical therapy sessions are more productive, as well as gym workouts and gardening activities. I haven't experienced any unpleasant side effects."

• Dee...
• Taken for less than 1 month
• April 7, 2025

"Because I am fast metabolizing all opioids, my meds need to be periodically either adjusted or changed to something else. I was switched to Hysingla ER 60 with Tramadol for breakthrough three times a day. The H worked the very few days, then, at least after midnight, I am in complete pain and withdrawal. It doesn’t work for me for more than 12-14 hours a day. And Tramadol is not strong enough, nor can I ever wait for 8 hours for a pill for break pain. These rules should not be so, for not everyone is the same. We are each individually different, and our bodies completely act differently to medication and pain."

• lor...
• Taken for 1 to 6 months
• August 29, 2015

For Pain "Does not cure pain, nor does it last anywhere near 24 hours - more like 10. Complete garbage."

• Spa...
• Taken for less than 1 month
• February 5, 2015

For Pain "At my job, I needed medication that would last for up to two shifts or more, 16 to 20 hours a day. I have been taking Hysingla ER 40 mg tablet, what a big difference."

• Coc...
• July 20, 2015

For Pain "I take 120 mg at night, but it takes approximately 6 hours to start working and is completely worn off approximately 16-18 hours after the dose."

• Boo...
• November 26, 2015

For Pain "I have been on the pain patch, but it gave me such headaches. I've been on Hysingla for a few months at night, I take it. I only sleep 4 to 5 hours a night. When it works, it's amazing."

• Unk...
• Taken for 1 to 6 months
• January 15, 2017

For Pain "Irregular inconsistency on pain control. Many breakthrough pains throughout the day. Helps with low pain and mild pain, but not for breakthrough severe pain."

• cra...
• Taken for 1 to 6 months
• May 4, 2017

For Pain "My hair is falling out by the handful!"

• Anonymous
• Taken for 1 to 6 months
• September 12, 2017

For Pain "Does not work for my chronic pain."

• Ake...
• February 20, 2018

For Pain "Has been a big change in pain level. But believe I need a breakthrough pain med also."

• Hel...
• Taken for less than 1 month
• April 3, 2020

For Pain "Just started Hysingla ER. Along with 10-325 Percocet three times a day. Hysingla not helping at all. No relief."

• Anonymous
• Taken for less than 1 month
• November 20, 2017

For Pain "Terrible, did nothing for pain. All I did was sleep and feel lethargic. Pain increased dramatically. I am totally miserable."