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Hysingla ER and Drowsiness: What Users Say

Drowsiness: mentioned by 5 users (5.1%)

Based on user experiences from 98 Hysingla ER reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 11.2%
withdrawal 11.2%
tiredness 10.2%
nausea 9.2%
pain 9.2%
drowsiness 5.1%
anxiety 4.1%
constipation 3.1%
fatigue 3.1%

Reviews for Hysingla ER

Commonly mentioned side effects
  • 3le...
  • Taken for less than 1 month
  • August 29, 2015

For Pain "30 mg was good, but 40 mg took my pain away, it was heaven. Except that 40 mg made me so tired and drowsy that all I did was sleep. I couldn't function, so that's not acceptable. I would go to bed at 7 pm and wake up at 4 pm the next day! So I'm going back to 30 mg with breakthrough meds. But here is the thing I can't figure out... I take up to 10-15 mg hydrocodone for breakthrough pain ON TOP of my Hysingla ER 30, but that doesn't make me sleepy, it actually kind of keeps me up at night. How bizarre is that? It's the same dosage but reacts completely different. That annoys me because the 40 worked perfectly!!! Except for the severe drowsiness. How can Hysingla ER 40 mg be so much more sedating than Hysingla ER 30 mg with 10-15 mg hydrocodone on top???"

7 / 10
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65 Report
  • 3le...
  • Taken for less than 1 month
  • August 29, 2015

For Pain "30 mg was good, but 40 mg took my pain away, it was heaven. Except that 40 mg made me so tired and drowsy that all I did was sleep. I couldn't function, so that's not acceptable. I would go to bed at 7 pm and wake up at 4 pm the next day! So I'm going back to 30 mg with breakthrough meds. But here is the thing I can't figure out... I take up to 10-15 mg hydrocodone for breakthrough pain ON TOP of my Hysingla ER 30, but that doesn't make me sleepy, it actually kind of keeps me up at night. How bizarre is that? It's the same dosage but reacts completely different. That annoys me because the 40 worked perfectly!!! Except for the severe drowsiness. How can Hysingla ER 40 mg be so much more sedating than Hysingla ER 30 mg with 10-15 mg hydrocodone on top???"

7 / 10
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65 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • November 4, 2016

For Pain "This drug didn't work as well as short-acting hydrocodone in lower doses. I had to take up to 20 mg of Tramadol per day for breakthrough pain on top of the 30 mg of Hysingla. It put me to sleep, made me unable to think clearly or efficiently, and didn't allow me to organize my day or complete my tasks as well as I previously had. I had to take it around 6 PM to avoid breathing issues when I lay down, and as a result, by the time I got up in the morning, I no longer received any pain relief from it - there is no way it works for 24 hours. I'm now in the process of returning to Norco, and while still taking hydrocodone, I am experiencing withdrawal symptoms from getting off the Hysingla. It is far more dangerous and addictive than it is promoted."

1 / 10
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37 Report

Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • October 1, 2016

For Pain "Hysingla really keeps the pain level from my fibromyalgia in check. I no longer feel I am on a pain scale roller coaster. I stay around a 3-4 most days. Others sometimes a 6, but no longer am I at an 8-20 on the pain scale. I also love that I don't feel dopey or tired from the Hysingla version like with Norco."

9 / 10
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33 Report
  • Mrs...
  • Taken for 1 to 6 months
  • January 12, 2016

For Pain "24-hour medicine for pain. I only got 6 hours of minimal relief. Started on the 20 mg for 1 month, then Dr. switched me to 40 mg for 1 month, then 30 mg for 1 month. It always seemed to start working long after I took it, about 12 hours, and made me extremely sleepy and tired, along with pain. In the 3 months I took it, I gained 15 pounds without even eating more or differently because I was constantly nauseous with it. Who wants food when queasy? I have been prescribed an instant release pain med and have been on it for 2 days. It works great with no side effects, and I have lost the 7 lbs of the 15 that Hysingla made me gain. Hopefully, the other 8 lbs will come off quickly too because the weight gain from the drug caused my A1C to go"

1 / 10
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28 Report

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