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Hysingla ER and Constipation: What Users Say

Constipation: mentioned by 3 users (3.1%)

Based on user experiences from 98 Hysingla ER reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 11.2%
withdrawal 11.2%
tiredness 10.2%
nausea 9.2%
pain 9.2%
drowsiness 5.1%
anxiety 4.1%
constipation 3.1%
fatigue 3.1%

Reviews for Hysingla ER

Commonly mentioned side effects
  • Kri...
  • Taken for 1 to 6 months
  • June 13, 2019

For Pain "Tried morphine and Percocet for severe, intractable pain from injuries and surgery. Hysingla was then prescribed as those did not help. Hysingla did nothing for my pain and also made my head feel swimmy, and it’s very constipating, like severely. The doctor tried Norco, and I’m finally pain-free most of the day now, the first time in years. I really can’t say why Hysingla didn’t work because Norco is the same ingredient, but it didn’t work for me and Norco really does work for me. Like, amazingly. And I’ve never had to step up the dosage nor ever had addiction or withdrawals to pain medication. (Only Cymbalta for me was highly addictive and took me over a year to get off of it. Withdrawal was severe. Strange because they say opioids are not safe, but for me, they are, and antidepressants were not. Very strange.)"

2 / 10
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57 Report
  • Yog...
  • Taken for 1 to 2 years
  • June 8, 2019

For Pain "I have CRPS (complex regional pain syndrome), which is one of the worst chronic pain conditions known to man, and I get a lot of relief from this medication. Prior to Hysingla, I was prescribed Opana ER until it was taken off the market, and I must say I'm thankful for the change. I like the fact that it works without making me feel 'drugged.' The only downside is constipation that requires daily doses of laxatives. There aren't many extended-release choices, but hopefully, more options will become available soon for people that aren't getting relief from Hysingla."

10 / 10
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31 Report
  • ton...
  • Taken for 1 to 6 months
  • July 20, 2017

For Pain "I have 3 herniated discs, spinal stenosis, and osteoarthritis. I suffer from constant pain every day. I've been on Norco 10/325 4x a day for 3 years now and never abused my medication. A few months ago, my doctor had me try Hysingla ER 40 mg. This medication only lasts about 17 hours and gave me about 30-40% relief with random breakthrough pain. Plus, I felt lethargic the entire day, nauseous, constipated, anxious, and excessive yawning. After putting up with it for two months, I talked with my doctor, and he switched me back to the Norco. So disappointed. I had high hopes for this medication since it was one pill every 24 hours. It just does not work as promised and is expensive."

2 / 10
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29 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.