Hydrochlorothiazide / lisinopril User Reviews & Ratings (Page 3)
Brand names: Zestoretic
Hydrochlorothiazide / lisinopril has an average rating of 5.2 out of 10 from a total of 78 reviews on Drugs.com. 32% of reviewers reported a positive experience, while 36% reported a negative experience.
Reviews for Hydrochlorothiazide / lisinopril
- Anonymous
- Taken for 1 to 2 years
- April 6, 2020
For High Blood Pressure "Constant dry cough. Frequent urination throughout the day. My physician increased from 20 mg to 40 mg. Still had side effects. Physician added Losartan and the cough went away, but I would feel numbness in my right leg and tingling in my right foot."
- Bet...
- Taken for 2 to 5 years
- January 8, 2022
For High Blood Pressure "This medication almost crippled me! Over the course of a year, my joints became so painful that I could barely climb or descend stairs without crying out in pain. This just started out of nowhere; I was perfectly able-bodied then - crippled. I started researching arthritis, MS, etc. On a side note, I ran out of blood pressure meds and went without for almost 2 weeks. Miraculously, my legs and knees got noticeably better each day! I figured it was a coincidence and started my BP meds again. All the joint pain came back. I did not truly make a connection until I stopped my meds again for 3 days, and I was able to deal with the stairs almost pain-free! This time I am convinced there is a connection with the Lisinopril HCTZ and looked online: there it is - muscle and joint pain! It is worth noting that I was on this med for 2 years before this happened to me. It does control my BP. So, it can start at any time. Be aware."
- Rea...
- Taken for 2 to 5 years
- January 12, 2022
For High Blood Pressure "I was on this for 3 years. Just the 10 mg, and then I’d cut that pill in 1/2. It really worked to keep my BP safe. I did have an occasional tickle cough. Then summer came, and I burned like I never had before. My eyes couldn’t handle any sunlight without a burning feeling. It was terrible. I eventually took myself off the medicine, and my sun problems cleared up within a week."
- HCM...
- Taken for 6 months to 1 year
- February 7, 2023
For High Blood Pressure "I was prescribed Lisinopril-HCTZ 20/12.5 mg for high blood pressure. After about 2 weeks on it, I developed a dry cough that continued throughout the day and night. I consulted with my doctor, who said the cough was due to allergies and to try Claritin, which did not work. Two months later, I was told to try Zyrtec, but that did not work either. After 8 months of chronic coughing, I looked into the side effects of lisinopril and found that dry cough was one side effect. I changed doctors and was advised that I needed an ARB medication, not an ACE inhibitor. After a week on an ARB, the coughing has stopped. The only plus to the lisinopril is that it did regulate my blood pressure."
Are you taking this medicine?
Your review helps others make informed decisions.- Ang...
- Taken for less than 1 month
- June 13, 2022
For High Blood Pressure "I started on this medicine 5/4/22. Ended up with a 2-day stay in the hospital because of it 6/5/22. Within 3 days of starting it, I got a terrible ringing in my ears. To the point I couldn't hear the TV. Next, every time I stood up, leaned over, or turned my head too quickly, I got terribly dizzy. Then my feet and ankles got so sore it was really hard to walk. I stopped taking it on a Sat and went to the Dr. Mon morning. Dr. told me I'd feel a lot worse if I had a stroke. But he cut down to half a pill. I took the half pill for about 5 more days, and by then I felt unsafe even walking inside my own home. Between the dizziness and terribly sore feet, I was very unsteady. At the ER, they tested my potassium level, and it was way too low. Under 2.5. So I had an IV for a day and a half. I think this is supposed to be easy on your P levels, but for some reason, it did a number on mine! I still can't walk right, I just hope it clears up. And my BP has been 90/60 w/o meds, so I have no idea, but I will never take it again!"
- swe...
- Taken for 5 to 10 years
- April 24, 2025
For High Blood Pressure "This drug works well for controlling my blood pressure. If I do anything physically exerting, I get muscle cramps in various locations like legs, arms, fingers. The only way to stop these cramps is to take an electrolyte drink, like Liquid IV, Powerade, Gatorade, etc. These electrolyte drinks can get rid of the cramps within 15-20 minutes. However, they contain salts, which works against the lisinopril/HCTZ. In my case, the increase in blood pressure from these drinks is very small. It may not be so small for others. My doctor is aware of this and told me I can use these drinks, but not excessively. I hope this helps others facing severe muscle cramps associated with this medication."
- Mar...
- Taken for 5 to 10 years
- November 13, 2022
For High Blood Pressure "20/12.5 lisinopril, I have been on this medication for about 7 years now. Everything was fine until 3 months ago when my upper right arm began to ache. It was annoying, but I was managing fine. 2 weeks ago, my left upper arm began to ache. It has gone from annoying to having a very difficult time getting dressed. Although it keeps my blood pressure in check, it has started to cause major disruptions in my physical abilities. I am only 52 and usually very active. I have made an appointment with my doctor and am looking into natural remedies."
- Mmd...
- Taken for 2 to 5 years
- May 23, 2023
For High Blood Pressure "This particular generic pill does not work. I've been on the blue octagon-shaped generic (works excellent) and the peach round generic form (works okay). This is the first time I've been given this white round generic form, and it does nothing for lowering blood pressure. I may have been given placebos. I could tell by a dull headache and realized I'm not peeing like I normally do on this med. I then checked my blood pressure, 141/98. Med was taken at 6 am, and I monitored it every three hours throughout the day. Never went below 128/88."
- All...
- Taken for 2 to 5 years
- July 12, 2013
For High Blood Pressure "I have been on this medication for several years now. I have none of the side effects that others speak of. My blood pressure is consistently in the normal range. Very happy with it. I'm 45."
- MJa...
- Taken for 1 to 6 months
- September 10, 2018
For High Blood Pressure "Leg cramps, pins and needle feeling in heels, can't sleep. I take 2.5 mg."
- Anonymous
- April 25, 2012
For High Blood Pressure "Side effects included coughing at night and during the day. Just no control over it. I was on a half-dose regimen, and with exercise and diet, my blood pressure was dropping."
- 150...
- August 31, 2008
For High Blood Pressure "After one week on Lisinopril HCTZ, my blood pressure went from 150/94 to 124/74. I am experiencing the coughing side effect, though, which is distracting during conversation."
- Anonymous
- February 28, 2009
Hydrochlorothiazide / lisinopril for High Blood Pressure "I do very well on this medicine. I started out at a higher dose. I am now down to 5 mgs. I am 76 years young. I stopped smoking on October 4, 2007."
- Zoe...
- July 28, 2016
For High Blood Pressure "Headaches. Dry eyes. Aches. Excruciating pain in feet. Insomnia. This stuff is poison."
- Anonymous
- August 12, 2015
For High Blood Pressure "Side effects: muscle pain and weakness!"
- lit...
- January 6, 2009
Hydrochlorothiazide / lisinopril for High Blood Pressure "It works great for blood pressure, but there is a tickle cough associated with it."
- Ang...
- December 31, 2015
For High Blood Pressure "This medication seems to work for me. No side effects thus far that I am aware of. Have been taking this med a long while."
- diz...
- Taken for less than 1 month
- June 13, 2018
For High Blood Pressure "Day 3. BP 84/37, dizzy, tired. Stopped taking on my own."
- Yos...
- Taken for 6 months to 1 year
- September 28, 2020
For High Blood Pressure "It has my whole body cramping: arm, leg, feet, all over, charley horses."
- Ali...
- March 23, 2018
For High Blood Pressure "I had to take this medicine for high blood pressure and it was horrible. I had headaches and stomach cramps."
- Nor...
- February 21, 2009
For High Blood Pressure "I started this drug a few weeks ago, and along with Coreg, has done wonders for my blood pressure. However, I am experiencing the 'cough.'"
- Jim...
- January 30, 2017
For High Blood Pressure "You get very itchy and nauseous, don't like it. All blood pressure medicines have terrible side effects. More research has to be done on these medicines."
- njg...
- February 12, 2009
For High Blood Pressure "My mom started taking this medicine since last week and has started coughing. Her doctor had to switch her from Hyzaar to this medicine as her insurance no longer covered Hyzaar."
- chr...
- February 18, 2011
For High Blood Pressure "Good medicine, no problems at all."
Are you taking this medicine?
Your review helps others make informed decisions.More about hydrochlorothiazide / lisinopril
- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: ACE inhibitors with thiazides
- En español
Patient resources
- Hydrochlorothiazide and lisinopril drug information
- Lisinopril and hydrochlorothiazide (Advanced Reading)
- Lisinopril and Hydrochlorothiazide
For High Blood Pressure "I have been taking it off and on for many years. Back when I first started to take it, back around 20 years (I'm 47 now), it worked. No side effects. Started taking it again for around 8 months now. Side effects galore. Itchy throat, legs and big toe cramps, numbness in my arm, backache, headache, dizzying, and sleep is like never enough but can't not work. Checking with my doctor Friday to see what are my other options. BP is all over the scale."