Hydrochlorothiazide / lisinopril and Cramps: What Users Say

• Jak...
• Taken for 1 to 6 months
• May 10, 2021

For High Blood Pressure "It's just okay. Lowered my BP marginally. However, the coughing, constant acid reflux, and muscle aches are terrible. Both of my shoulders and forearms are sore and tingly - this was never an issue until I started this medication. I've woken up with severe leg pain and cramps. I've gone to the doctor, and they've run every test possible, and nothing shows up as being wrong; so it has to be this medication."

• Sus...
• Taken for 1 to 6 months
• August 29, 2018

For High Blood Pressure "Explosive watery diarrhea, without warning, no cramping, no stomach upset, it just pours out of me without notice. I have taken Immodium like candy while I'm working. Leg cramps, almost every night. I thought medicines were supposed to make you better, not worse. It has helped my BP, but it has made the rest of my life awful. I tell my doctor, and nothing. She does nothing."

• fox...
• December 9, 2009

For High Blood Pressure "Although Lisinopril-Hydrochlorothiazide worked very well for lowering my blood pressure and not causing swelling, there were some problems that have caused me to seek a different solution to my high BP. The first thing that occurred was sudden, painful night leg cramps. This happened each night from 1 to 5 times. I also had new painful attacks of arthritis in my toes and instep. I also had warnings of kidney stone formation and crystals in my urine. Finally, I experienced heaviness in my legs that made it difficult to walk quickly."

• tri...
• January 1, 2013

For High Blood Pressure "Minor: For about an hour after taking, I have to pee a lot. MAJOR: Sometimes, very bad foot pain/cramps to the point of hardly being able to walk. I take this and amlodipine for high blood pressure, and it works."

• Sia...
• July 21, 2017

For High Blood Pressure "Took myself off of the drug because my BP was at pre-hypertension, and I had this constant dry cough. I used to have horrible leg cramps at night... no matter how much water I drank before bed. I never use salt or eat salty foods; the doctor said to eat more bananas. I never made the connection to the cramps and the meds, and my doctor did not, either. Well... I wondered why I haven't had any leg cramps in months, and my boyfriend said, 'You stopped taking your blood pressure medicine.' Duh!"

• MJa...
• Taken for 1 to 6 months
• September 10, 2018

For High Blood Pressure "Leg cramps, pins and needle feeling in heels, can't sleep. I take 2.5 mg."

• Yos...
• Taken for 6 months to 1 year
• September 28, 2020

For High Blood Pressure "It has my whole body cramping: arm, leg, feet, all over, charley horses."