Simponi User Reviews & Ratings (Page 3)

• Anonymous
• Taken for 1 to 6 months
• October 12, 2022

For Rheumatoid Arthritis "This is terrible stuff. Made my RA worse. Caused side effects of extreme fatigue, muscle pains, psoriasis on my scalp and dermatitis, and my hair has been falling out. Also causing my lymph nodes to swell. It has been 3 months, so I am trying something else and will discontinue. Wish I never tried."

• Pat...
• Taken for 1 to 6 months
• April 9, 2016

For Ankylosing Spondylitis "Well, I would like to say Simponi has been very effective for me. From my first shot to the sixth, the shot I just received this month, the Simponi removed my symptoms of AS to the point where I feel normal. Before being diagnosed and receiving Simponi, I was in pain constantly and taking meds that were basically for gout, which is what I was being treated for before my diagnosis for AS. One month, the doc tried Remicade, but it was ineffective for me. The Simponi has given me back normality, at least in the sense of physical well-being. It has been wonderful for me and my family, as they don't have to worry about helping me when I have symptoms of swelling and pain. In fact, I noticed that when I get scratches, my wounds even heal faster. Thanks."

• Kev...
• October 12, 2015

For Psoriatic Arthritis "It seemed to work well for me right from the start. I had been on Remicade previously, but I had to quit due to losing my insurance. By the time I went to Simponi, I was hurting pretty bad. Unfortunately, it stopped working after a while (18 months), but that has been my personal experience with biologics. When it worked, it worked well."

• PsA...
• Taken for 6 months to 1 year
• January 30, 2020

For Psoriatic Arthritis "I tried Simponi for 9 months for psoriatic arthritis. At first, it was like a miracle. Then the pustular psoriasis started on my legs, my hair started falling out, and my mood got very strange. Bloodwork showed super high cholesterol, which was 3 times what it ever was. Psoriasis flared worse than ever all over my body. My skin has never gone back to normal. Terrible, scary drug. Wish I'd never tried it."

• LVe...
• Taken for 5 to 10 years
• October 17, 2022

For Rheumatoid Arthritis "Simponi has been the most effective biologic for me. I've used (infusions or injectable) Humira, Enbrel, Orencia, Remicade, and Simponi. I have been on Simponi 3 times as long as any other medication. Over 6 years of effectiveness. I take one 50 mg syringe monthly, and although I still struggle with fatigue, flares are managed as well as joint degeneration."

• Aus...
• Taken for 1 to 2 years
• November 3, 2020

For Ankylosing Spondylitis "I have ankylosing spondylitis, which was diagnosed 4 years ago due to a very bad case of uveitis. I was given three TNF blockers without success. I was offered Simponi, and this one worked, the pain went away after a few days, and I was very happy about that, as AS is very painful, and it explains why I had a sore back for most of my life. I am now 58 years old. I did not get any side effects, but it did raise the blood pressure, which I already have hypertension, so it's made that worse, and I cannot get my BP under control. It did not stop the uveitis from reoccurring, but overall it has worked well."

• Mel...
• March 18, 2017

For Ulcerative Colitis "Simponi did not work for me. Tried it three months, and it made all the bleeding, cramping, and diarrhea worse. I really wanted it to work for me, but it didn't. And Janssen was no help, called it 'side effects,' when it was 'exacerbation of symptoms.' Best wishes if you take it, I hope you find success with it. :)"

• Anonymous
• October 2, 2009

For Psoriatic Arthritis "My husband took his first dose last month and is getting ready to take his second dose in a few days. While I think the drug is working, the Patient Cost Support Program is difficult to deal with, and we are still struggling to get reimbursement."

• Nat...
• Taken for 5 to 10 years
• October 8, 2020

For Ankylosing Spondylitis "Been on Simponi for 8 years. Has been amazing, turned my life around. It can get sore within a week of injection, but not sure if that can be helped. Tried Enbrel and Humira previously, but they only worked for 6 months for me."

• tng...
• Taken for 1 to 2 years
• February 5, 2013

For Ankylosing Spondylitis "I have narcolepsy and ankylosing spondylitis, I also suspect that I have psoriasis on my scalp but haven't had it diagnosed officially yet. Simponi relieves some of the pain and discomfort from the AS, and I usually have no lesions on my scalp while I am using the injection regularly. I also take 5 tabs of methotrexate weekly (along with all the side medications that go along with these). I recently came down with a bad cold and was taken off these medicines temporarily. Immediately upon missing my injection, my symptoms were back. The lesions started to appear on my scalp and are pretty bad. I would say that my quality of life has significantly improved since starting the Simponi about a year and a half ago. I take one injection per month."

• Nic...
• Taken for less than 1 month
• August 30, 2019

For Ankylosing Spondylitis "Faced severe neurological and ophthalmological side effects after the first injection of Simponi. Reduced/blurred vision, constant dizziness, unsteadiness, balance issues, cognitive problems, tremors, etc. It’s been two weeks after the injection... still facing all these side effects."

• Pip...
• Taken for 1 to 6 months
• July 8, 2015

For Psoriatic Arthritis "I have now just taken my 4th injection. I'm as bad as I was, if not worse than when I was first diagnosed. I can barely walk, have swelling in my toes, feet, and ankles, as well as my left knee. Also in my elbows, wrists, hands, and fingers... I have bad psoriasis on my scalp. I don't think this medication is very good at all and have shown no response to the previous 3 doses, and this dose I have been nauseous ever since taking it. I was on Humira previously for about 5 years, but I stopped responding, and Enbrel I had really bad reactions to... Hoping for something new when I go back to the specialist at the end of the month."

• mik...
• Taken for 1 to 6 months
• June 16, 2018

For Ankylosing Spondylitis "I'm suffering light to moderate AS for 8 years, and pain comes with activity. I used it only once, seems like it's good for 3 months for me. I was suffering from a light cough and shortness of breath due to a cold when I did the shot. Pain was gone in a couple of days, quality of life increased noticeably, but cough and shortness of breath continued heavily for 2 months. Make sure you have no cold symptoms before you make the shot."

• Tho...
• Taken for 1 to 6 months
• January 27, 2021

For Psoriatic Arthritis "An absolute life changer. From living in excruciating pain each day and struggling to get out of bed - to being absolutely pain-free in a matter of only 3 months. No limitations as to what I can do physically, and the psoriasis on my scalp has cleared significantly. I have slight hand tremors, but that causes me no trouble and may be due to other causes (23 years old, dosage once every 4 weeks)."

• Joh...
• Taken for 2 to 5 years
• October 27, 2013

For Ankylosing Spondylitis "Simponi helps me so much. I take 2 shots per month. I was diagnosed about 7 or 8 years after my first signs of illness. I've had it very hard. I get OxyContin when I have it too hard. But all in all, Simponi is the best. I got a new life with it. Works as a chef, and without Simponi, I would not. I live in Sweden, so I only pay about $300 a year. Or else I would have to pay a lot, like $4000 per month. The negatives with this med, you can get a lot of crap from it. But the pain I had before was crazy. Thank you, my sweet doctor."

• Phi...
• Taken for 1 to 6 months
• June 20, 2019

For Ankylosing Spondylitis "Took only 2 injections! After the second, became very ill, had a 104 temp, and then ended up in the hospital with a spinal infection! I then was transported to a specialty hospital 2 hours away via ambulance due to the increasing swelling of the spinal cyst I developed, full of infection, and they feared I might need intubation, but the cervical spine is fused, so I needed to be at a different hospital! I spent a total of 14 days in the hospital, 10 of which in ICU, then 14 weeks at home with a PICC line and heavy-duty antibiotics! All due to Simponi!! This almost bankrupt our family, I almost lost my LIFE and job!"

• rrs...
• December 5, 2017

For Psoriatic Arthritis "I was on Remicade infusion for 7 years, I had wonderful results for 6 years, with PSA flares slowly creeping back in the 7th, but not unmanageable. Rheumy switched me to Simponi. After 2 injections, while my skin is still clear, the PSA is raging. I am in terrible pain. I spoke to my Rheumy once, and she said to give it a chance. Calling her again this morning. The pain and exhaustion are debilitating and affecting every aspect of my life. I asked her about Taltz and Cosentyx, but she wanted to keep me on a TNF blocker. I'm ready for change."

• Kin...
• Taken for 1 to 6 months
• January 11, 2023

For Rheumatoid Arthritis "I was taking Enbrel previously and found that it helped, but my doctor moved me on to Simponi. I have done two infusions of Simponi and developed psoriasis on my face, which is painful. The doctor has told me I have had an allergic reaction to this medication. I have had an allergic reaction to a similar medication, Humira. If you can't take Humira, do not use Simponi."

• Joj...
• November 9, 2020

For Rheumatoid Arthritis "I've had 2 Simponi infusions. Recently, I started breaking out with hives, especially on my legs and feet. Sometimes on my arms and the backs of my hands. It itches terribly but clears up within 30 minutes to an hour. But it's been happening every day for about 2 weeks now. Is this a common side effect of this drug?"

• Cir...
• Taken for 6 months to 1 year
• August 28, 2021

For Rheumatoid Arthritis "Diagnosed with RA in March of 2020 at age 65, it hit me like a Mack truck. Would have been in a wheelchair within a year. Started on methotrexate, which got me maybe 90% there. After 6 months, started the Simponi, I feel completely normal now. Stopped the methotrexate in February. It is now August 2021, and I'm feeling great, no restrictions - workout all the time. Do it as an IV every 60 days."

• jen...
• February 7, 2014

For Psoriatic Arthritis "I took Simponi for 8 months before stopping to get pregnant with my son. All of my symptoms had disappeared, and I was 100% flare-up free. However, after having my little guy and starting the Simponi injections again, I have not had any relief from my psoriasis and have experienced 2 flare-ups even after upping my dose to every 3 weeks. How can it have worked so well and now not well at all? I have requested an appointment with my rheumatologist to discuss other biologic medicines."

• Fuz...
• Taken for 6 months to 1 year
• November 12, 2019

For Ankylosing Spondylitis "Simponi is my 4th TNF blocker that I have tried. Upside - I have no pain anymore, and I am grateful for that. I have not experienced any side effects and have been on it for 7 months now. I guess I will continue to use it until there is a reason not to. Downside - it killed my sex drive and has made my testicles shrink, and I now produce very little sperm. My stomach has bloated since starting Simponi also."

• Ras...
• Taken for 6 months to 1 year
• August 24, 2019

For Ankylosing Spondylitis "I have had a hard time with drugs for my ankylosing spondylitis (A/S), and I thought Simponi was going to be the miracle one. The problem is that it doesn't last the full term they say it does. I have 5 weeks of feeling pretty darn good and 3 weeks of suffering. The infusion is supposed to last 8 weeks."

• deb...
• Taken for 1 to 6 months
• April 20, 2023

For Rheumatoid Arthritis "I have had two infusions so far. The first one made me feel really good, but the second one did not so much. The third one is coming up shortly, and I am hoping it helps. I had no side effects from either infusion."

• Anonymous
• June 18, 2011

For Ankylosing Spondylitis "Was diagnosed with osteoporosis in 2000 and ankylosing spondylitis in 2003. I have been put on different medications for both. I have been on Simponi for about 6 months and have not noticed any improvement. It is easy to use, but that is about all."