Simponi User Reviews & Ratings (Page 3)

• Patrick...
• Taken for 1 to 6 months
• April 9, 2016

For Ankylosing Spondylitis "Well, I would like to say Simponi has been very effective for me. From my first shot to the sixth the shot I just received this month the Simponi removed my symptons of AS to the point where I feel normal. Before being diagnosed and receiving Simponi I was in pain constantly and taking meds that were basically for gout which what I was being treated for before my diagnosis for AS. One month the doc tried Remicade but it was ineffective for me. The Simponi has given me back normality at least in the sense of physical well-being. It has been wonderful for me and my family as they don't have to worry about helping me when I have symptoms of swelling and pain. In fact I noticed that When i get scratches my wounds even heal faster. Thanks,"

• Melis...
• March 18, 2017

For Ulcerative Colitis "Simponi did not work for me. Tried it three months, and it made all the bleeding, cramping and diarrhea worse. I really wanted it to work for me...but it didn't. And Jannssen was NO help...called it "side effects," when it was "exacerbation of symptoms." Best wishes if you take it...I hope you find success with it. :)"

• Linda
• Taken for 1 to 6 months
• May 14, 2023

For Rheumatoid Arthritis "I have been on every oral drug for treatment for RA. I then was prescribed Orencia subcutaneously for 2.5 years. I still had to use prednisone 15-25mg on a regular base when I worked. Orencia did not show any real change in my symptoms. I then changed to Simponi 50mg subcutaneously monthly. I could feel a difference after the very first injection. After 3 weeks my swelling and moderate to severe symptoms of RA improved. Following my second injection I noticed an over 50% improvement in my fatigue. As of now after my third injection, I can mostly claim I am improved by at least 80% of overall symptoms. Morning stiffness, my pain, my energy levels. In closing, without trying to sound dramatic I can confidently say Simponi 50mg subcutaneously monthly has overall improved the quality of my life by 90%."

• tngst...
• Taken for 1 to 2 years
• February 5, 2013

For Ankylosing Spondylitis "I have narcolepsy and ankylosing spondylitis, I also suspect that I have Psoriasis on my scalp, but haven't had it diagnosed officially yet. Simponi relieves some of the pain and discomfort from the AS and I usually have no lesions on my scalp while I am using the injection regularly. I also take 5 tabs of methotrexate weekly (along with all the side medication that goes along with these). I recently came down with a bad cold and was taken off these medicines temporarily. Immediately upon missing my injection my symptoms were back. The lesions started to appear on my scalp and are pretty bad. I would say that my quality of life has significantly improved since starting the Simponi about a year and a half ago. I take one injections per month."

• Johan...
• Taken for 2 to 5 years
• October 27, 2013

For Ankylosing Spondylitis "Simponi helps me so much. I take 2 shots per month. I Washington diagnosed about 7 or 8 years after mycket first signs of illness. Ive had it very hard. I get oxycontin when i have it too hard. But all in all, simponi is The best. I got a new life with it. Works as a chef, and without simponi i would not. I live in sweden, so i only pay about $300 a year. Or else i would have to pay ALOT. like $4000 per month. The negatives with this med, you cancer get alot of crap from it. But the pain i had before was crazy. Thank you my sweet Dr."

• Nathan
• Taken for 5 to 10 years
• October 8, 2020

For Ankylosing Spondylitis "Been on Simponi for 8 years. Has been amazing turned my life around. It can get sore within a week of injection but not sure if that can be helped. Tried Enbrel and Humira previously but they only worked for 6 months for me."

• Danni
• Taken for 6 months to 1 year
• April 1, 2023

For Rheumatoid Arthritis "While on Simponi I developed severe diarrhea. I was on this awful drug for 11 months. When I started Simponi I weighed 125 pounds I now weigh 101 pounds. After I stopped taking Simponi on my own I can't gain back the weight I lost and I am sick all the time I feel like my body is attacking me. My doctor wouldn't believe that Simponi caused diarrhea and the awful way I felt. I stopped Simponi a month ago and haven't had any signs of diarrhea. I still feel awful but I'm hoping to get my health back. You have to find a doctor who really listens when you talk which unfortunately I did not."

• Phil
• Taken for 1 to 6 months
• June 20, 2019

For Ankylosing Spondylitis "Took only 2 injections! After the second became very ill had a 104 temp and then ended up in the hospital with a spinal infection! I then was transported to a specialty hospital 2 hours away via ambulance, due to increasing swelling of the spinal cyst I developed full of infection and they feared I may need intubation, but cervical spine is fused so I needed to be at a different hospital! I spent a total of 14 days in hospital 10 of which in ICU , then 14 weeks at home with a picc line and heavy duty antibiotics! All due to simponi!!!!!!! This almost bankrupt our family,I almost lost my LIFE and job! "

• LVettel
• Taken for 5 to 10 years
• October 17, 2022

For Rheumatoid Arthritis "Simponi has been the most effective biologic for me. I've used (infusions or injectable) Humira, Embrel, Orencia, Remicade and Simponi. I have been on Simponi 3x's as long as any other medication. Over 6 years of effectiveness. I take one 50mg syringe monthly and although I still struggle with fatigue, flares are managed as well as joint degeneration."

• Nick
• Taken for less than 1 month
• August 30, 2019

For Ankylosing Spondylitis "Faced severe neurological and ophthalmological side effects after first injection of Simponi Reduced/blurred vision, constant dizziness, unsteadiness, balance issues, cognitive problems, tremors etc. It’s been two weeks after injection.. still facing all these side effects."

• Anonymous
• Taken for 1 to 6 months
• March 17, 2022

For Rheumatoid Arthritis "I started Simponi infusions , just recently my first infusion was fine, made me a bit tired but no side effects and no effects at all, my 2nd infusion was 3 weeks ago, I again was tired after the infusion but I was more tired than usual , I started not feeling real great, the next day I felt even worse I believe every side effect that this drug has I had, fever, cold chills, nausea, extremely fatigued, headache, my whole body has and still is swelled up 2 x more than normal, having trouble breathing I then ended up with sinus infection and then pneumonia. Let me say that I have been dealing with RA/Fibromyalgia for the past 23 years, I have been on everything and anything that is available as suffice to say nothing has worked for me, however I never had any side effects to this magnitude with the others. I am glad this works for others and was really hoping to finally get some relief but I guess my body is rejecting this medication so I feel I had better listen to it."

• Circuit...
• Taken for 6 months to 1 year
• August 28, 2021

For Rheumatoid Arthritis "Diagnosed with RA March of 2020 at age 65, hit me like a Mach Truck. Would have been in a wheelchair within a year. Started on methotrexate, which got me maybe 90% there. After 6 months started the Simponi, feel completely normal now. Stopped the methotrexate in February. It is now August 2021 and feeling great, no restrictions - workout all the time. Do it as an IV every 60 days."

• Pipar...
• Taken for 1 to 6 months
• July 8, 2015

For Psoriatic Arthritis "I have now just taken my 4th injection, I'm as bad as I was if not worse than when I was first diagnosed. I can barely walk, have swelling in my toes, feet and ankles, as well as my left knee. Also in my elbows, wrists, hands and fingers ... I have bad psoriasis on my scalp. I don't think this medication is very good at all and have shown no response to the previous 3 doses and this dose I have been nauseous every since taking it .. I was on Humira previously for about 5 years but I stopped responding and Embrel I had really bad reactions too ... Hoping for something new when I go back to specialist end of month"

• Fuzzy...
• Taken for 6 months to 1 year
• November 12, 2019

For Ankylosing Spondylitis "Simponi is my 4th TNF blocker that I have tried. Upside- I have no pain anymore and I am grateful for that. I have not experienced any side effects and have been on it for 7 months now. I guess I will continue to use it until there is a reason not too. Downside- it killed my sex drive and has made my testicles shrink and I now produce very little sperm, my stomach has bloated since starting Simponi also."

• Rastas
• Taken for 6 months to 1 year
• August 24, 2019

For Ankylosing Spondylitis "I have had a hard time with drugs for my ankylosing spondylitits (A/S) and I thought Simponi was going to be the miracle one . The problem is that it doesn't last the full term they say it does. I have 5 weeks of feeling pretty darn good and 3 weeks of suffering. The infusion is supposed to last 8 weeks."

• mike
• Taken for 1 to 6 months
• June 16, 2018

For Ankylosing Spondylitis "I'm suffering light to moderate AS for 8 years and pain comes with activity. I used only once, seems like its good for 3 months for me. I was suffering light cough and shortness of breath due to cold when I did the shot. Pain gone in couple days, life quality increased noticeably but cough and shortness of breath continued heavily for 2 months. Make sure you have no cold symptoms before you make the shot."

• Jojo
• November 9, 2020

For Rheumatoid Arthritis "I've had 2 Simponi infusions. Recently I started breaking out with hives, especially on my legs and feet. Sometimes on my arms and backs of my hands. It itches terribly, but clears up within 30 minutes to an hour. But it's been happening everyday for about 2 weeks now. Is this a common side effect of this drug?"

• jenni...
• February 7, 2014

For Psoriatic Arthritis "I took Simponi for 8 months before stopping to get pregnant with my son. All of my symptoms had disappeared and I was 100% flare up free. However, after having my little guy and starting the Simponi injections again I have not had any relief to my psoriasis and have experienced 2 flare ups even after upping my dose to every 3 weeks. How can it have worked so well and now not well at all. I have requested an appointment with my rheumatologist to discuss other biologic medicines."

• rrsltx
• December 5, 2017

For Psoriatic Arthritis "I was on Remicade infusion for 7 years, I had wonderful results for 6 years, with PSA flares slowly creeping back in the 7th, but not unmanageable. Rheumy switched me to Simponi. After 2 injections, while my skin is still clear, the PSA is raging. I am in terrible pain. I spoke the my Rheumy once and she said to give it a chance. Calling her again this morning. The pain and exhaustion is debilitating and affecting every aspect of my life. I asked he about Taltz and Cosentyx but she wanted to keep me on a TNF blocker. I'm ready for change."

• Thommo
• Taken for 1 to 6 months
• January 27, 2021

For Psoriatic Arthritis "An absolute life changer. From living in excruciating pain each day and struggling to get out of bed - to being absolutely pain free in a matter of only 3 months. No limitations as to what I can do physically, and the psoriasis on my scalp has cleared significantly. I have slight hand tremors but that causes my no trouble and may be due to other causes (23 years old, dosage once every 4 weeks)"

• Anonymous
• Taken for 1 to 6 months
• October 12, 2022

For Rheumatoid Arthritis "This is terrible stuff. Made my RA worse. Caused side effects of extreme fatigue, muscle pains, psoriasis on my scalp and dermatitis and my hair has been falling out. Also causing my lymph nodes to swell. It has been 3 months so I am trying something else and will discontinue. Wish I never tried"

• Anonymous
• June 18, 2011

For Ankylosing Spondylitis "Was diagnosed with osteoporosis in 2000 and ankylosing spondylitis in 2003. I have been put on different medications for both. I have been on Simponi for about 6 months and have not noticed any improvement. It is easy to use but that is about all."

• tc31w...
• Taken for 1 to 2 years
• June 24, 2016

For Ankylosing Spondylitis "I'm a 48 year old female that started showing symptoms at age 17, diagnosed at 19 with the HLA-B27 marker. Total hip replacement at 29, chronic chest pain due to fusing. I have tried a butt load of meds over the years, most oral due to lack of insurance (Which thankfully, I now have) which cost me renal failure stage 2 including Methotrexate. I have a Medtronic pain pump and am on Oxycodone currently too. I have tried Enbrel, Humira and now Simponi. Simponi works very well for me WHEN I can get the smart injections to work. "

• Mano
• Taken for 1 to 6 months
• September 30, 2019

For Ankylosing Spondylitis "I've been diagnosed with AS since 2010, but symptoms started since 2008. Started Simponi last month & was on my 2nd shot last week. 1st shot had been great but after the 2nd shot, I am experiencing constant dizziness."

• gmoro
• Taken for 1 to 6 months
• July 30, 2015

For Spondyloarthritis "Been on this for 2 and a half months. After the second injection, I went 13 days without taking any Norco or Soma whereas I typically took one a day and two a day respectively. It took a bit to get my insurance to cover it, but I had a severe reaction to Humira allowing me to. Amazingly it seems to work even better than my enbrel at 11 weeks."