Simponi and Tiredness: What Users Say

• gre...
• Taken for less than 1 month
• May 11, 2017

For Rheumatoid Arthritis "I had my first infusion today. No ill effects with the exception of exhaustion...additional, that is, as I already am sleeping 16 hours per day. Not sure how a person is supposed to make a living with this advanced RA. I am hoping that Simponi will resolve that in the near future. I will let you know when things start to work and I can return to the land of the living."

• Qwa...
• February 3, 2017

For Rheumatoid Arthritis "Yesterday, I got my 4th injection in 4 months at home by a nurse! I think it's working very well so far... I have taken many other types of medicines over 7 years with big side effects for RA. I have had Ulcerative Colitis for 15 years and took some meds for that. Because of side effects, I began a very stringent diet (specific carbohydrate diet). I eventually got better, and all UC symptoms stopped. Years later, I went off the diet and was soon reduced to suffering immensely with undiagnosed RA symptoms. I believe my diet contributes to my symptoms. I know food chemicals can cause inflammation, and I know UC is a cousin to RA. I come from generations of alcoholics and am recovering for 27 years. Sugar is a deadly and strong addiction. Today, I was lethargic."

• Anonymous
• Taken for 1 to 6 months
• March 17, 2022

For Rheumatoid Arthritis "I started Simponi infusions. Just recently, my first infusion was fine, made me a bit tired, but no side effects and no effects at all. My second infusion was 3 weeks ago. I again was tired after the infusion, but I was more tired than usual. I started not feeling real great. The next day, I felt even worse. I believe every side effect that this drug has, I had: fever, cold chills, nausea, extremely fatigued, headache. My whole body has and still is swelled up 2 times more than normal, having trouble breathing. I then ended up with a sinus infection and then pneumonia. Let me say that I have been dealing with RA/Fibromyalgia for the past 23 years. I have been on everything and anything that is available. Suffice to say, nothing has worked for me. However, I never had any side effects to this magnitude with the others. I am glad this works for others and was really hoping to finally get some relief, but I guess my body is rejecting this medication, so I feel I had better listen to it."

• rrs...
• December 5, 2017

For Psoriatic Arthritis "I was on Remicade infusion for 7 years, I had wonderful results for 6 years, with PSA flares slowly creeping back in the 7th, but not unmanageable. Rheumy switched me to Simponi. After 2 injections, while my skin is still clear, the PSA is raging. I am in terrible pain. I spoke to my Rheumy once, and she said to give it a chance. Calling her again this morning. The pain and exhaustion are debilitating and affecting every aspect of my life. I asked her about Taltz and Cosentyx, but she wanted to keep me on a TNF blocker. I'm ready for change."

• Ani...
• Taken for 1 to 6 months
• July 1, 2022

For Ankylosing Spondylitis "Used for psoriatic arthritis and ankylosing spondylitis. Seriously multiplied my pain by at least 10, psoriasis was also much, much worse than I’d ever had it previously. Extremely tired, asleep more than awake, terrible pressure felt on the top of my head daily, stuck with it for 5 months in the hope it would settle. No such luck in my case… could say it was worth trying, however, it really, really wasn’t. Wish I never used it at all."