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Cymbalta User Reviews & Ratings (Page 5)

Cymbalta has an average rating of 6.3 out of 10 from a total of 1,900 reviews on Drugs.com. 53% of reviewers reported a positive experience, while 30% reported a negative experience.

Reviews for Cymbalta

Commonly mentioned side effects
  • WSR...
  • Taken for 1 to 6 months
  • July 28, 2020

For Osteoarthritis "Cymbalta changed my life. I started using Cymbalta for severe chronic lower back pain. My pain was so bad I considered suicide on many occasions. After failed back surgery, over-the-counter medications, epidurals, spinal ablation, and everything else imaginable, my pain doctor prescribed Cymbalta. The side effects from Cymbalta were horrible, but within 2 weeks my back pain completely disappeared. I still deal with the side effects, and Cymbalta is a highly addictive drug that is near impossible to withdraw from. I have come to terms with the alternatives and have decided Cymbalta is worth all of the negatives. It has saved my life."

10 / 10
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  • Adu...
  • Taken for 1 to 6 months
  • August 29, 2017

For Chronic Pain "I suffer from chronic pain, depression, and anxiety for the past 10 years and I'm 30. Football ruined my life, but Cymbalta has made it worse. Not only did I NOT receive any benefit from Cymbalta, but I gave it a serious 2-month try and I'm now spending 90% of my time withdrawing from it. I cannot imagine if I was on this a year, let alone ten. If this medicine helps you, I would weigh the benefits seriously because either you're going to the grave with this medicine or you're going to have to feel the 'benefits' of coming off of this poison. Beware because no doctor will tell you these things. Worse than 2 years of clonazepam, alcohol, or opiates, no joke. Hope this helps someone!"

1 / 10
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  • Jus...
  • Taken for less than 1 month
  • October 18, 2020

For Depression "Have been on Cymbalta for a week now for depression and chronic pain. Feel like an absolute zombie, have struggled to get my daily things done and have otherwise stared at the TV all weekend. Scared to stop because of all the horrid reviews but want to continue for the promising reviews. Why does treating depression have to be so hard? I feel worse than I did last week. Numb to the world. No motivation or desire to participate in life. I will persevere for another week and reassess. I am taking it in the morning, perhaps I need to take it at night? I think I will do that this week. No change to my pains."

1 / 10
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Frequently asked questions

  • Jud...
  • Taken for 10 years or more
  • June 20, 2019

For Fibromyalgia "I suffered from the pain of fibromyalgia for 20 years, and I got my life back after I started to use Cymbalta. I have no more pain, other than that of many 71-year-olds. I consider myself one of the very fortunate people that it works so well for me. I can take fitness classes now and feel the improvement from them tremendously. I also think that what likely helped me work, etc., when I had the symptoms was the fact that I did mild exercise six mornings a week for 20 minutes on the recommendation of an amazing doctor who recognized what I had before most people had even heard of it and told me exercise was supposed to help. I walked up and down my stairs then used a cross-trainer (slowly) - when my husband decided I was wearing out our carpet!"

10 / 10
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  • Dan...
  • June 17, 2015

For Generalized Anxiety Disorder "I have been on Cymbalta for a week now, 30mg twice a day. I have no side effects at all! From the first dose, I noticed a huge difference, it calmed me right down! Before this med, I was mad at everything, almost in a constant panic mode, not sleeping, and in a lot of pain. I have low back nerve pinching, bulging, degenerative discs, and fibromyalgia. I can't say enough good about this medicine, it has really changed my quality of life, my outlook. I feel like I did 20 years ago, before my anxiety took over my mind. My blood pressure is also back to normal. Being stressed at every little thing made mine go up. I love this medication, I wish I had gotten it a lot sooner, better late than never!!"

10 / 10
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  • the...
  • Taken for less than 1 month
  • December 18, 2018

For Generalized Anxiety Disorder "I have tried a long list of antidepressants, including older ones, newer ones, and most of the meds in between. Cymbalta is the only one that has helped me. I have only taken it for about a week, but I already feel the effects for my GAD and Panic Disorder. I am so thankful for this drug. Bless you all, don't be afraid to try meds, and keep on fighting if you haven't found one that has worked for you yet. Hugs, The User"

9 / 10
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  • wfe...
  • Taken for 2 to 5 years
  • September 29, 2014

For Depression "EXCELLENT results. Effexor became non-effective after many years of use and another life-impacting event. Was recently severely depressed and suicidal for about 2 years. Found Cymbalta 2 years ago, and it CHANGED MY LIFE FOR THE BETTER. I think this medication is FANTASTIC. I have been diagnosed with major depressive disorder and general anxiety disorder (dual diagnosed). This condition has been with me for many years (runs in the family, i.e., mother was severely depressed). Cymbalta 120mg per day snapped me out of it. Under doctor's orders, I discontinued the current SSRI at the time and started right up with Cymbalta 120mg/day. Within 7-10 days, I was out of my depressed state. It has to be the norepinephrine aspect that made the difference."

10 / 10
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More FAQ

  • Anonymous
  • Taken for 1 to 6 months
  • November 2, 2018

For Fibromyalgia "After years of chronic pain, headaches, fatigue, insomnia, intermittent depression, and anxiety, I did my research on fibromyalgia and had a conversation with my doctor. I had read about Cymbalta, and my doctor agreed to prescribe it and see if it would help my multiple issues. I felt better after the first day of 30 mg of Cymbalta. The only side effects I had were insomnia and daily headaches the first week. My side effects were tolerable, and the benefits outweighed the side effects. I stuck with it and have now been on Cymbalta for 4 weeks. I'm so thankful for this medication and feel I have my life back! I took high-dose Xanax for years, I couldn't fall asleep without it. I have been able to wean off Xanax as well, something I had been unable to do before. I see my doctor again this week and can't wait to tell her how well Cymbalta helps me."

10 / 10
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  • DSu...
  • Taken for 10 years or more
  • June 30, 2019

For Depression "I have been taking Cymbalta for approximately 15 years for depression and anxiety. I had tried every other drug on the market. It has been a lifesaver for me! The first few days I felt nauseous, but that is a side effect that goes away. My doctor told me it was one of the few that continues to work after taking it for a long time. I mistakenly have quit taking it a few times to see if I felt better. I had no adverse effects coming off of it, except that my anxiety and depression worsened. This year was the first time I’ve had my dosage increased since starting the medication. As long as it continues to work, I’ll never quit taking it."

10 / 10
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  • Rsa...
  • Taken for less than 1 month
  • July 20, 2019

For Back Pain "I started 30mg Cymbalta 3 weeks ago for my neck and lower back pain. I feel so much better now. I went through weird side effects and lost appetite. I was afraid to take this medication after reading the reviews but everyone is different. I’ve been able to work and workout without pain. Cymbalta worked pretty well for me."

10 / 10
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  • Ami...
  • Taken for 6 months to 1 year
  • May 2, 2020

For Chronic Pain "Cymbalta has been the worst drug I've ever been on and was irresponsibly prescribed by my doctor for chronic pain. I was on it for 4 months, and it didn't work at all. To make it worse, I almost died from withdrawal because my doctor took off for 3 months and left no one in his place to write my prescription. Therefore, I went into withdrawal, which he never warned me about. This drug is worse than any opiate. If you take your medication responsibly, you shouldn't be denied other more helpful medication."

1 / 10
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  • Jlc...
  • Taken for 6 months to 1 year
  • January 23, 2019

For Chronic Pain "Put on Cymbalta 30 mg with intentions of going up to 60 mg. It was for anxiety, panic attacks, chronic pain from back surgery, stenosis of spine and cervical fusion. I have taken it for 7 months. HAD NO side effects EVER. It helps me sleep at night. My pain, anxiety, and panic attacks are minimal. Only complaint is that I have gained 10 lbs and I am hungry all the time. I am still taking 30 mg."

10 / 10
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  • Aus...
  • Taken for 1 to 6 months
  • March 17, 2021

For Anxiety "I feel so lucky, this has gone beyond my expectations. I don’t ever want to be off it. Only side effect has been constipation but I feel so good I don’t care. Even if I forget to take the tablet I have NO SIDE EFFECTS! I was really hesitant to start this as the reviews didn’t seem so good but it truly is an individual experience."

10 / 10
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  • Cym...
  • April 23, 2017

For Depression "Cymbalta has been an incredible drug for me. Since taking Cymbalta, I have been able to enjoy life more, sleep less, and feel more refreshed - reduction in pain, and improved memory and concentration. Recently, I have been studying for an exam. This is a hard exam that I previously failed before while not taking Cymbalta. I started taking Cymbalta approximately in January. The months leading up to the exam, I was more focused and able to concentrate better than I can last remember. I know that Cymbalta doesn't treat concentration or memory problems, but I think that sometimes if you are depressed, it can have a severe effect on concentration. Thank you, Cymbalta, for helping me in my life."

10 / 10
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  • Cie...
  • Taken for 5 to 10 years
  • September 24, 2019

For Chronic Pain "I have rheumatoid arthritis that was not responding to Orencia, Arava, Rituxan, Cimzia, or Humira. Prior to these medications, I was on Enbrel, but it stopped working after 9 years and I was allergic to methotrexate. The Cymbalta seemed to make my pain much more bearable. I still had the joint pains, but somehow, the pain wasn't such a massive ordeal. Oh, and it also nicely treated my chronic major depressive disorder as well. I thought that maybe if I was on a higher dose, I might have less pain, so my dose of generic (Lupin) duloxetine was increased up to 150mg a day, and I found that although I could function fine during the day, I could not sleep. It was like I was too keyed up or something. Not anxious, just keyed up. I was able to sleep once I dropped my dose back down to 120mg a day. I give Cymbalta a 10 because it is a single medicine that treats two medical conditions!"

10 / 10
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  • Tin...
  • Taken for 1 to 6 months
  • May 14, 2019

For Fibromyalgia "Cymbalta has changed my life for the better. Besieged by terrible leg pains and tingling for over 6 months, I tried gabapentin and other drugs but hated how they made me feel. 20mg of Cymbalta started working almost immediately, and has helped me gain my quality of life back. The other positive thing: I've always been anxious and thought it was just part of my DNA, but then I've noticed much of the daily anxious thoughts have gone away since taking this drug. Very grateful."

9 / 10
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  • Joh...
  • Taken for 10 years or more
  • February 4, 2024

For Chronic Pain "I have been on Cymbalta (60 mg/d, ER) since late 2009. My Dr. prescribed it for pain from stenosis and bone spurs in my cervical vertebrae. It took a few weeks to work. When it did, my neck pain went down so much that I completely forgot about my neck. It continues to work now even after 14+ years. I am writing this review because I am away from my home for 3 days and forgot to pack my Cymbalta. It is Sunday, and I haven’t taken Cymbalta for three days. My neck pain came back this morning like the pre-Cymbalta days. Is this a coincidence? Perhaps, but I was virtually pain-free for over 14 years until I missed three doses in a row. I will be back at home tonight and will take my Cymbalta the very minute I walk in the door. I recommend Cymbalta wholeheartedly."

10 / 10
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  • Jay...
  • September 6, 2018

For Anxiety "I had pain throughout my entire body. I felt like I was dying. My moods were at an all-time low for months. No ambition, just wanted to sleep and give up on life at age 45. I had been on other medicines for several years, they worked ok, but I still had issues. I just tried to cope with them until it became too much. I am on day 2 of Cymbalta 60mg, and I can already feel the difference. I wake up feeling alive, and I’m not hurting all over my body. My mentality is about 80% better already. Thank goodness this worked!! I hope it helps others as much as it has helped me!"

10 / 10
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  • Jan...
  • Taken for 10 years or more
  • September 17, 2019

For Depression "I have been on Cymbalta for ten years. It immediately helped my fibromyalgia pain and worked awesome for my depression. I was on 60mg for about 5 years, and now on 90mg for 5 years. I tried to come off it, so for one month, I took 60mg last February. The symptoms were unbearable. I felt bee stings everywhere, and I mean literally everywhere. My legs were in so much pain, my whole body felt like it was shaking inside. I had flushing, a fever, non-stop itching. The list goes on. It definitely served a wonderful purpose when I started, I just kinda feel cheated they didn’t tell me I have to stay on for the rest of my life."

8 / 10
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  • jom...
  • September 27, 2007

For Pain "Cymbalta provided amazing relief for my neuropathic pain and depression, though it also seemed to have bad side effects. The night terrors I experienced were unimaginable and occurred almost nightly. I had taken this medication for over a year, and after choosing to discontinue it, the withdrawal symptoms that followed seemed severe. I would advise a cautious approach."

9 / 10
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  • meg...
  • Taken for less than 1 month
  • April 30, 2020

For Fibromyalgia "I was prescribed Cymbalta 30 mg for Fibro & nerve pain. I took one pill. I had never had a panic attack in my life until taking this medicine. I took the pill at 10:30 am. At 12:30, I couldn’t catch my breath. My heart started pounding. My vision became a tunnel, and I felt like I was about to pass out. The only thing I could do was lay down and breathe deeply. Things calmed down. I got up from the bed, and wham! It hit me again. This time, however, my skin started burning. My chest and arms felt like they were on fire. I couldn’t breathe again, my vision went tunnel-like again. Ringing ears, pounding heart. Even my feet started itching really bad. The panic attacks were severe. The ER told me I had to let the medicine run its course, and they gave me a Xanax to help calm the panic attacks. It took 18 hours. The Xanax helped. It was the worst day and night of my life! The doctor said my reaction was not a normal reaction. I couldn’t believe one single pill did this to me."

1 / 10
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  • Gin...
  • June 13, 2015

For Depression "My experience on Cymbalta has been rather a positive one. As mentioned by others, in the first 2 weeks, it does have side effects. I felt tired and was a little nauseous. I was put on Cymbalta as the entire country that I live in ran out of my previous medicine. I have suffered from anxiety, OCD, and depression on and off for a few years. Since Cymbalta has 'kicked in,' I have hardly any anxiety and no depression. I think clearly and rationally and not as emotionally as I always used to. I still do not have an appetite, and I have been on this for over a month now. When I sleep, I sleep soundly and am able to fall into a deep sleep as well. I highly recommend Cymbalta and am very happy with the positive effects it has had on me."

8 / 10
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  • blu...
  • Taken for less than 1 month
  • December 25, 2020

For Chronic Pain "One of the worst medications ever. 1st 5 days, had no desire to do anything. Complete apathy about everything. Also had terrible nausea for 5 days. That finally went away. Then it started feeling like something was literally tapping on my brain. It did nothing for the chronic pain I had. I don't know how anyone can take this medicine. Stopped taking it. Had a headache for a few days, that was it."

1 / 10
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  • CJa...
  • June 15, 2019

For Depression "I am prescribed this medication for over-focused ADHD and depression. Before trying this medication, I was on Adderall once and Modafinil once, all for a short time. The Cymbalta medication has really helped me. The pain of depression is gone, my thoughts are in a better scope, and I don't feel as deeply and get into moods. While not feeling as deeply might sound bad to some people, it is a real issue for me. With my depression at bay, I'm much more able to focus on what I need to do and do it with a good attitude. I notice I don't obsess over things as much and am able to be present in the moment, and easily change my train of thought to the next thing. I'm very happy I trusted my doctor on this because, at first, I really didn't like the idea. I know this is temporary, but I trust in the medication to put me in a safe place. Understand that the bad reviews are obvious in that some people were simply misdiagnosed. I have no negative side effects at all."

10 / 10
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  • jef...
  • February 18, 2014

For Fibromyalgia "I've been on antidepressants for years and suffered from chronic pain that was finally diagnosed as fibromyalgia. I started on Cymbalta about 5 years ago because the pain was becoming more than I could deal with and my doctor had read good reviews about patients' reactions with this medicine. I never had any problem with the medicine and haven't noticed any major side effects. It has really cut the pain to a manageable level and kept my spirits up."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.