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Cymbalta User Reviews & Ratings (Page 2)

Cymbalta has an average rating of 6.2 out of 10 from a total of 1,764 reviews on Drugs.com. 53% of reviewers reported a positive experience, while 30% reported a negative experience.

Reviews for Cymbalta

  • Calig...
  • Taken for less than 1 month
  • January 15, 2020

For Chronic Pain "I have been on Cymbalta for 3 weeks and feel great — free of spine pain and aches that follow surgeries. No longer am I taking pain meds or high doses of aspirin. Keep pinching myself that this is real!"

10 / 10
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235 Report
  • Loz
  • Taken for 6 months to 1 year
  • June 17, 2019

For Generalized Anxiety Disorder "I have anxiety, panic disorder, autism, ADHD, sensory processing disorder. Overall I have had a very positive response to duloxetine. Side effects: There is the initial fatigue & a lot of yawning. That went away after about 3 weeks. I had difficulty peeing during the night. This faded over time. Difficulty to orgasm after I went up to 90mg, this faded after a few weeks. This medication makes my brain work better & gives me a better quality of life and an opportunity to live rather than just survive. If you identify with any of my symptoms & have been recommended duloxetine by your doctor, I say it is worth giving it a try. When it is the right medication for you it is life changing! And please don't rush to come off them. If you need them you need them and that's okay. They are your friend. I feel grateful that science has given me this opportunity to support me."

9 / 10
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258 Report
  • Anonymous
  • September 15, 2009

For Depression "Cymbalta is the best thing that I have ever tried and for more than just depression. I also suffered from debilitating anxiety. Both have all but disappeared. Before I started taking it about 4 months ago I literally hoped I would just fade away. I wanted to die so badly it's all I thought about. I have lost 45 pounds along with my compulsive overeating disorder and have gained more peace and happiness than I ever knew could exist for me. It saved my life (and helped me be a much better mother, wife, daughter-everything). I will deal with the super sweatiness and a few extra yawns during my day in order to have a life. Viva la Cymbalta!"

10 / 10
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578 Report

Frequently asked questions

  • Chris
  • Taken for less than 1 month
  • September 18, 2020

For Depression "I’ve been taking Cymbalta at a dose of 40 mg for 1 week now, I feel light headed. Not really depressed or having anxiety, but I can’t sleep and I have no appetite. I’m already under weight. Feeling stoned all day. My stomach also churns all night. I think there must be something more tolerable for me. I can’t function. Any suggestions?"

4 / 10
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201 Report
  • Sandr...
  • July 21, 2016

For Chronic Pain "I was prescribed 20 mg of Cymbalta three days ago. The agonizing pain in my knees is virtually gone. Not kidding! All the negative posts almost made me quit. Don't give up. I was offended that my doctor prescribed this medication as it is an antidepressant. I convinced myself I wasn't suffering depression I was suffering from chronic pain. Come on people! Who, if you are in chronic pain isn't depressed? I couldn't do anything anymore. I couldn't get out in the garden, couldn't cook for my family, couldn't walk up or down stairs without leaning on the rails. I know it's too soon to tell but I know it is doing what ever it's suppose to do in my brain to cut out the pain."

8 / 10
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Are you taking this medicine?

  • danimom
  • Taken for 1 to 6 months
  • July 2, 2014

For Anxiety "I was quick to anger, severe mood swings would yell at my kids for the slightest things. I was ready to punch anybody that would make me mad and( it didn't take much!) I started with Cymbalta 30mg and I noticed a slight difference I was increased to 60 mg and I felt the change right away. I'm so calm and I'm back to being a happy mom. I take it at night because it would get me sleepy during the day if I take in the morning some of the side effects I've experienced have been dry mouth, lack of appetite, hot flashes, tiredness! I love this medicine it has changed my life. The relationship with my children is much much better too. I no longer have crying spells and I'm a much nicer person. Try Cymbalta."

9 / 10
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401 Report
  • Derobyn
  • Taken for 1 to 6 months
  • July 20, 2021

For Chronic Pain "I began Cymbalta about a month ago after telling my new MD that I had aches/pains everywhere and was not sleeping because of it. She began me on 60mg and after a month, I am now not having the pain that I had before. I have had 3 nights in a row of getting into bed and being comfortable and can rest and sleep! I read all of the reviews I could, and saw all of the negative ones. Everyone is different, please don't think because someone else had a bad experience that you will too."

9 / 10
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151 Report

More FAQ

  • jim
  • Taken for 1 to 6 months
  • July 21, 2019

For Chronic Pain "I've been on Cymbalta 20 mg for about 5 weeks which was prescribed for chronic hip/lower back pain. Day 2 into the medication the hip/lower back pain was gone! Doc upped the dosage to 40 mg....day 1 after taking 40 mg the arthritis on both hands/fingers was gone also. Very minimum side effects."

10 / 10
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221 Report
  • Bromis
  • Taken for 1 to 6 months
  • October 10, 2018

For Depression "Cymbalta has literally changed my life. My brain was always in this constant fog, I could never think straight about anything and intrusive thoughts about suicide would pop into my mind constantly. I didn’t care about anything and struggled to find my motivation. Now I’m thriving in work, taking pride in my appearance and being a much nicer person. I’m brighter, happier and just a much better person to be around. My colleagues and family have all noticed the change. Before I started taking it i’d read so many bad things about it, I almost didn’t try it. I’m so glad I did. I feel like the person I always dreamed I could be. I can think clearly and I’m not riddled with anxiety anymore."

10 / 10
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243 Report
  • Jamie...
  • Taken for 6 months to 1 year
  • February 20, 2018

For Fibromyalgia "I started taking Cymbalta for fibromyalgia in July of 2017. Prior to this, I was already taking Prozac for anxiety and depression, so making the switch seemed logical. The Cymbalta would help with those symptoms, while also combating the pain and fatigue I was experiencing from fibromyalgia. Honestly, it's been life-changing for me. I feel like my old self again. I'm relatively pain free and my energy levels are up. Prior to starting Cymbalta, the pain was so bad that I wanted to die. I even told my husband to divorce me because I didn't want him to be saddled with taking care of me. I was sleeping my life away, missing out on dinner and time with my family. I wore my hair in a bun every day because I didn't have the energy to even hold the blow dryer. It was really bad. I'm 95% back to who I was before fibro entered my life. I would highly recommend Cymbalta to any other fibro fighters out there."

10 / 10
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257 Report
  • Clare...
  • Taken for 1 to 6 months
  • March 4, 2014

For Depression "Cymbalta literally saved my life. After going through 6 psychiatrists and countless other antidepressant attempts, this is the one that finally worked. I promise that if you hold on and keep fighting something will work for you and you can heal. Depression is never permanant."

10 / 10
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352 Report
  • Amos
  • Taken for 6 months to 1 year
  • October 13, 2018

For Anxiety "Cymbalta changed my life. I was going through the worst life experience I could imagine. Thoughts of suicide dominated my life and panic attacks were often. Then I started taking Cymbalta and everything changed. I started having the ability to see a hopeful future and my panic attacks disappeared. The days I forget to take it look grey until I take it and hope returns. I'm too fearful to exist drug-free in my later years. I've never experienced any side effects, just positive ones. I wish I had started taking something like this when I was young. To me, it's a miracle drug."

10 / 10
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223 Report
  • Much...
  • April 30, 2014

For Depression "I had mild anxiety and intermittent depression. I always pushed through and never thought of medicines. My girlfriend suggested I speak to a psych and I started Cymbalta. In 10 days I had no more intrusive thoughts talking me down, making me stressed, guilty. After 9 weeks, I'm a new man. Small things don't worry me, I am patient and calm driving, I don't wake up for toilet then stay awake worrying, my relationship is closer, I'm nicer to be with. Cons? My libido decreased and climax is harder to achieve (but more intense). The medicine felt strange (out-of-body) at first but I got used to that. I drink more water, I yawn in the afternoons, I grind my jaw a bit, get breathless, mild headaches some days. But my life is much better with this medicine."

9 / 10
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  • Beth
  • Taken for 1 to 2 years
  • June 13, 2019

For Generalized Anxiety Disorder "One year Cymbalta honest review. I started Cymbalta about a year ago as I have struggled all my life with social anxiety and general anxiety. About a month before I started taking it, I started getting really bad anxiety attacks every day and had my first ever panic attack (Which prompted the doctor's visit for help).The first week was OK. I had no appetite and felt anxious all the time for no reason. Then, suddenly my whole mood changed and I became a lot more cheerful and talkative person. I actually wanted to do things, instead of stay at home. Note to everyone with bad reviews: this doesn't work overnight. It takes time for the chemicals in your brain to balance. I would say it takes 2 weeks to see some effects to take place, and at least a month or two to experience the full positive effects. But, it is so worth it! I highly recommend Cymbalta to those struggling with depressive thoughts or anxiety disorders! I have only had ONE anxiety attack since taking it, and no panic attacks"

9 / 10
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195 Report
  • Missy
  • Taken for 10 years or more
  • March 17, 2019

For Anxiety "Cymbalta worked to saved my life after perimenopause made my already existent depression increase tenfold. My depression was so dark I felt like I was being held down in a dark abyss. If I didn't seek medical help, I honestly believe I would have taken my own life. 60mg of Cymbalta daily and I could get out of bed, live my life, and function as a loving single parent who could provide for her family. Now, ten years later I will discuss the increasing anxiety I am feeling. Will my Cymbalta dosage increase. I don't know. But I do know for those 10 years I was not just surviving I was living. Thanks to Cymbalta"

10 / 10
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200 Report
  • Erin
  • Taken for 1 to 6 months
  • September 12, 2019

For Depression "I am 35 and have had depression and anxiety for many years. Over the years I have tried different SSRI’s- Zoloft, Prozac, Lexapro. They did nothing for me. I felt like I was taking a placebo. After a bad breakup about a year ago I experienced severe depression and my anxiety was through the roof. I went to go see a doctor and told him SSRI’s don't work for me! He said just give Cymbalta a shot, if it doesn’t work in a month or two we will try something different. I thought what do I have to lose? Within a couple weeks I could tell a difference in my mood. I was shocked because like I said, these drugs have never worked for me. Within a month I felt totally back to my normal self. No more depression and my anxiety has been drastically reduced! This drug has been awesome for me."

9 / 10
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181 Report
  • Banny
  • August 19, 2016

For Fibromyalgia "I started on 30mg Cymbalta 3 weeks ago, mainly for Fibromyalgia and anxiety. Initially, I experienced extreme nausea, apathy, sleepiness and brain fog. I read reviews which said, stick with it, so I did! My first night of taking it, my head was buzzing, I was awake all through. So I decided to take it in the morning, but I slept most of the day. No good! I reverted back to taking it at 7.30 in the evening, with food. Over the last 3 weeks, I stopped noticing any side effects and I slept like a log! Fabulous! My pain is now less, I feel really motivated and my brain is now as it was years ago! I actually feel that I have more wisdom and intelligence! I am more outgoing and sociable and life is worth living! Give it a chance!!"

9 / 10
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261 Report
  • Avie
  • Taken for 5 to 10 years
  • February 16, 2020

For Fibromyalgia "Hi. Just want everyone to know that I have been on Cymbalta (Duloxetine) for 5 years. It has been a lifesaver for me. I had a ruptured disc and sciatic nerve pain going down my buttock and leg. This seemed to affect my nervous system. For lack of a better definition, I referred to this as fibromyalgia. I had all over body pain. Cymbalta helped with the pain almost immediately. Beware, and your health care provider should warn you about this, it will make you sick to your stomach the first 2 to 3 days. I used a lot of Pepto Bismal."

9 / 10
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157 Report
  • kazza
  • Taken for 1 to 6 months
  • October 4, 2018

For Chronic Pain "I don't usually leave reviews for anything and I researched this drug and saw so many negative comments about it so I thought I would leave a positive one. People seem to try this for 1 - 3 days and give up, how is this giving the drug a good chance at working? I have had chronic musculoskeletal lower back pain for just over a year now without any opiates working long term, so my doctor prescribed Cymbalta 30mgs to start with, yes I did have side effects... nausea, insomnia, lack of concentration, fainting, headaches etc but when you are desperate for pain relief you try anything and I stuck it out for the 2 weeks and all the side effects have gone, I now gone up to 60mgs and I feel this is kicking in quite nicely, I don't need my pain patches anymore etc"

8 / 10
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194 Report
  • KGalRu
  • Taken for 1 to 2 years
  • July 15, 2021

For Major Depressive Disorder "People please stop saying "don't recommend" Just like birth control, everyone reacts differently to meds. Just because it didn't work for you, doesn't mean it won't work for someone else. And maybe it will work for someone, it could totally change their life, and because of your review they may never want to try it. My sister tried Cymbalta and it didn't work for her, yet she told me to give it a try and it changed my life."

10 / 10
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113 Report
  • Johnnie
  • Taken for 1 to 6 months
  • October 6, 2014

For Depression "Tried most antidepressants, and I was ready to give up. I was tired of trying antidepressants, getting sick while I waited for the positives, only to find out it didn't really help. I've tried Prozac, Paxil (good but stopped working for me), Zoloft (allergic to it), Effexor, Citalopram (worst of all). I don't know what made me ask my doctor for Cymbalta, but I did. It started working the second day I took it! I have been slowly recovering from depression and getting my life back. I hope the same for the people who read this. Never give up hope!"

9 / 10
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284 Report
  • Tulsa
  • Taken for less than 1 month
  • July 6, 2019

For Chronic Pain "For nine years I had lower back pain due to a bulging disk. I also had aches/discomfort in the left hip that caused me to walk with a limp. My doctor prescribed Cymbalta for chronic pain and a few days later I noticed that the hip aches/discomfort and back pain were gone. I no longer walk with a limp! Very minor side effects."

10 / 10
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169 Report
  • Las
  • February 28, 2020

For Depression "I was on this medication over ten years ago. It took a month for the fog to lift once I had started it. But then I started to be paranoid reading about the cymbalta withdrawals on the internet. So I panicked went off it. I always start at the lowest dose possible and stay on it a month before increasing to the next to avoid being sick. And it’s the same thing when you want to get off these meds to avoid withdrawals. You go off as slow as possible. And I want to mention that these meds are metabolized by different enzymes in our body that we all have different levels of because of our DNA. So one person might need a lower dose of cymbalta than another because they metabolize it faster than others. The goal isn’t to get to the highest dose but the dose that works with your metabolism. Ten years later and I have Fibromyalgia too now so my new doctor decided to put me on cymbalta. I started at 20mg today and will stay with that dose for at least a month before I see if I need to go up. Remember Go Slow!"

9 / 10
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151 Report
  • jas
  • Taken for 6 months to 1 year
  • March 26, 2020

For Major Depressive Disorder "I’ve had Major Depressive Disorder for years, and Cymbalta genuinely gave me my life back. I had tried so many medications, therapy’s. I had been hospitalized 4 times, and nothing worked. Until I started Cymbalta. I remember being afraid of how happy I was. I didn’t know I could enjoy life like I was. I have experienced no side affects, and I thank god for this drug everyday."

10 / 10
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148 Report
  • Happy...
  • Taken for less than 1 month
  • April 8, 2014

For Generalized Anxiety Disorder "Wow. Cymbalta changed my LIFE! Prozac made me a zombie, as did Paxil, Xanax & Klonopin. I have depression & anxiety. Prozac seemed to have made my depression worse! But then...Cymbalta saved me. I'm so happy to be able to actually GET OUT of bed, not yell at the kids, etc. I experienced a mild euphoria at first, now, (it's been a week) I just feel happy and energetic! I really hope it keeps working!!"

10 / 10
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287 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.