Skip to main content

Trulicity and Vomiting: What Users Say (Page 4)

Reviews for Trulicity

Commonly mentioned side effects
  • tin...
  • November 21, 2022

For Type 2 Diabetes "This is my 2nd week. Not good. I thought last week the nausea and pain in the stomach was because I also took one of my other meds. Nope. It is this medicine. Last week I was so sick for 2 days. I took it Saturday afternoon and started belching sulfuric burps and farts. This morning... I started throwing up and bathroom runs starting at 6:30 a.m. All sulfuric smelling. Throwing up and smelling that makes me puke more. Will never take this again."

1 / 10
Was this helpful?YesNo
7 Report
  • Jax...
  • June 21, 2019

For Type 2 Diabetes "I took this injection, then read some reviews and smugly thought, 'Oh, these people must be exaggerating because I feel okay.' Then two days after taking it, the trouble began. It's great for people who want to lose weight from vomiting and pooping their entire skeleton and organs out. I've never felt so ill. The worst thing is halfway through this week my sugar levels went higher than pre-injection due to not eating or being able to keep down my other meds at all. Not one for me to try again."

1 / 10
Was this helpful?YesNo
15 Report
  • Atv...
  • November 9, 2016

For Type 2 Diabetes "I took the smaller dosage of 0.75 mg, thank God. The first two days were fine, then the third day everything went south. Blood sugar was 219, the highest I had ever taken. Woke up with an upset stomach, then diarrhea for 6-8 hours, then vomiting for 4-6 hours, then cold chills, a rash that turned to hives from crotch to knees, armpits to elbows, head itched, lips started getting puffy. This was all in 24 hours. It was horrible. Then the next 9 days it took to get completely out of my system. Every day I would have these with less severity. The hives were the only thing that did not recur. At times, I could not stand any clothes on, my body was that sensitive. I found from the doctor at the emergency room that the half-life of the drug was 5 days."

1 / 10
Was this helpful?YesNo
19 Report

Frequently asked questions

  • nug...
  • Taken for less than 1 month
  • October 9, 2016

For Type 2 Diabetes "I did my first shot 10 days ago. Side effects were the worst I've ever experienced on a medicine: extreme nausea, headache, vomiting, and the diarrhea was extreme and very bad smelling with bad smelling sulfur-like burps. I thought maybe I caught a bug, but after reading others' side effects, I'm sure it was the shot. My husband is totally against me taking it again, and I'm now agreeing with him. Yeah, my sugars went down because I couldn't eat for almost 9 days, and nausea medicine didn't help at all. You lose weight because you can't eat. I was really hoping this would help because I don't want to go on insulin. I finally took something for the diarrhea and am feeling almost normal again."

3 / 10
Was this helpful?YesNo
21 Report
  • Ima...
  • Taken for 1 to 6 months
  • May 22, 2019

For Type 2 Diabetes "Trulicity is the worst medicine for type 2 diabetes. I can't believe the FDA approved this poison. Severe tummy issues, nonstop runs, can't stop them with medicines. I ended up dehydrated and needed fluids. Thyroid cancer is a side effect? WHAT!!! The treatment is worse than the illness. I stopped after it only slightly lowered my A1C from 8.2 to 8.1. Not worth it. I lost weight, but only because I could not eat and vomited or pooped myself to death the whole time taking it."

1 / 10
Was this helpful?YesNo
18 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • LZa...
  • Taken for 1 to 6 months
  • August 12, 2018

For Type 2 Diabetes "Been taking for 9 weeks. Seeing huge difference in blood sugar numbers. Haven't had a new A1C yet, but it should be good. First week or two, some nausea, dizziness, and vomiting, but it didn't continue. Do have to be careful what you eat and how much. You're going to make yourself sick if you don't heed their warnings about eating too much at once. I give it a thumbs up."

9 / 10
Was this helpful?YesNo
14 Report
  • Osc...
  • March 23, 2017

For Type 2 Diabetes "I just want to say what a horrible experience using Trulicity. Every single side effect happened to me, and I used the low dose one. I had nausea, diarrhea, vomiting, upper, lower, and mid-abdomen pain. It was so bad that I dragged myself to my doctors, and they had to call an ambulance because my BP dropped to low levels. The nurse said I looked green. I got dehydrated, and a week after, my stomach was still gassy and in pain. I hope it works for some of you, but if you are considering it, be advised, I lost an unhealthy 12 lbs in a few days."

2 / 10
Was this helpful?YesNo
19 Report

More FAQ

  • KEM...
  • Taken for 6 months to 1 year
  • June 8, 2024

For Type 2 Diabetes "About 6 months ago at age 78, I began having high blood sugars and an A1c that was in the full-blown Type 2 diabetes range. Initially, my doctor put me on Metformin. It dropped my blood sugar so rapidly that I would have severe shakes, headaches, and nausea. Another oral medication did the same thing. I decided the cure was worse than the disease and refused additional treatment. My doctor talked me into trying one more time and prescribed Trulicity. The injection was painless, and the only side effect was a complete loss of appetite-an incredible benefit since my entire life has been a fight against constant overeating. In the preceding weeks, my A1c has dropped to the normal range, and I have lost 42 pounds. Providing the weight loss continues, I only have 18 pounds to go before my BMI will be normal. It has been many years since I could say that! I did eat a candy bar at Easter and ended up vomiting along with diarrhea...not going to do that again! For me, Trulicity is a miracle!"

10 / 10
Was this helpful?YesNo
3 Report
  • Gra...
  • Taken for 1 to 2 years
  • December 30, 2021

For Type 2 Diabetes "After Metformin was no longer keeping my numbers down, my doctor suggested we add a new medication. He gave me a sack full of free samples of Trulicity. He said it was wonderful and should get me back in line. I started out on the lower doses, then eventually went to the 1.5 dosage until my numbers started creeping up again. That was about the same time that the 3.0 and 4.0 dosages had first been approved. I was put on the 3.0 dose. It brought my numbers back down, but the side effects were magnified and became intolerable. I ended up with heartburn so bad I started having to take daily heartburn medication. Then I started having severe episodes of what I initially thought was food poisoning. I had sulfur burps with severe vomiting and diarrhea so bad I had to wear adult diapers during those episodes. It turned out to be medicine-induced gastroparesis and pancreatitis. The once weekly shot was convenient but not worth the horrific pain and suffering it caused."

1 / 10
Was this helpful?YesNo
9 Report
  • PH ...
  • Taken for less than 1 month
  • June 21, 2022

For Type 2 Diabetes "I have type 1.5 LADA, diagnosed 10 years ago. In recent years, my weight has fluctuated, and so my endo prescribed Trulicity in Feb 2021 to facilitate weight loss following my complaints. I only used it once. From the first injection, something didn't feel right. I went to work and had to be on my feet all day to help with an event. I could barely stand upright and had to leave early, feeling like I was going to vomit and pass out at the same time. I had to call out from work the following day, still feeling weak as I spent the entire day vomiting. Eventually, my mom brought me to the ER late that night. While I was in triage, after waiting for lab test results, the physician told me I was in DKA. I was admitted to the ICU, where I spent the worst week of my life dealing with IVs, heparin shots, EKGs, ultrasounds, and round-the-clock blood work. I had elevated LFTs, low WBC, and no desire to eat because of the drug's lasting effects. I lost 13 lbs in six days. Buyer beware."

1 / 10
Was this helpful?YesNo
7 Report
  • Pan...
  • Taken for less than 1 month
  • June 16, 2019

For Type 2 Diabetes "Avoid at all costs unless you want to feel very poorly! On 1st day of taking it I felt light-headed. 2nd day I was puking up and had harsh abdominal pains. 3rd day I felt very bloated and was letting out burps that smelled like sewage. The bloating is causing me pains from my lower abdomen to my chest. Also got bad diarrhea flushing out lots of water. I am on the 6th day after having my 1st injection and am still very bloated and in pain. Will not be taking Trulicity again!"

1 / 10
Was this helpful?YesNo
14 Report
  • Lot...
  • Taken for less than 1 month
  • February 16, 2017

For Type 2 Diabetes "Day two of taking the higher dose of Trulicity, I was so ill. My breath smelled like poop, and I kept burping with the most awful eggy/poopy breath. Later that night, I was violently sick, and it smelled again like poop and looked like it. I've never been sick with what looked like it should have come out the other end. Just started on a lower dose today, so hopefully don't get side effects like that again."

3 / 10
Was this helpful?YesNo
19 Report
  • Ter...
  • Taken for less than 1 month
  • May 30, 2016

For Type 2 Diabetes "The PA in my endo office thought I would benefit from this even though I'm type 1 but showing signs of insulin resistance. Taking this injection was one of the biggest mistakes of my life! I've experienced extreme nausea, severe headaches, and heartburn from mild to severe. I've vomited one time, which made me think back to when I had food poisoning from eating crab, which was an awful experience. It's now 5 days after taking the first injection, and the above symptoms have lessened. No real appetite, and when I do eat, my stomach is queasy. I will not be continuing with this medication."

1 / 10
Was this helpful?YesNo
18 Report
  • mag...
  • Taken for 1 to 6 months
  • June 8, 2019

For Type 2 Diabetes "I'm not sure how to rate Trulicity. It's done a great job in reducing blood sugar (my blood sugar is an average of 146, down from almost 200 average). A1C is 7.1, down from 8.7 in 3 months and 6 shots of 0.75 mg Trulicity in the last month and a half. I've experienced no discomfort from taking the shots, I most often feel nothing and rarely the faintest prick of the needle. The downside is the side effects that I've had: outrageous gas, vomiting, and diarrhea. Side effects start 2-3 days after taking the shot and can last up to 5 days so far. I'm going to reduce and change my diet to see if that reduces the side effects, or I'll have to try something else."

9 / 10
Was this helpful?YesNo
13 Report
  • Chu...
  • Taken for less than 1 month
  • December 4, 2019

For Type 2 Diabetes "Type 2 diabetes and PCOS. Injected Friday, very easy and painless. Felt a bit odd Saturday, worsening until early evening. Fell asleep on the couch. Woke up at midnight with severe nausea. Vomiting and diarrhea for 24 hours. Vile taste. Rested Monday with mild diarrhea. Awful burping. Went to work Tuesday, had to come home, diarrhea struck again. Both GP and Endo think gastro, but after reading this page, now I know the real reason. Not at work today, Wednesday, due to lethargy. Will try again tomorrow. Dreading the second injection on Friday. Can’t tell the impact on BSL because have barely eaten. Trying to keep fluid up, drinking sports drinks."

3 / 10
Was this helpful?YesNo
11 Report
  • JLe...
  • Taken for 1 to 6 months
  • May 29, 2023

For Cardiovascular Risk Reduction "I've been taking it for a couple of months now and have zero side effects, except when I eat fatty or sugary foods. I will get sick to my stomach and vomit. However, I don't mind it as it serves as a wake-up call! It keeps me aware of what I should not be eating in the first place. I hope it will continue to help with my blood sugar levels and weight loss. I am grateful for this medicine. Thank you!"

10 / 10
Was this helpful?YesNo
5 Report
  • Bib...
  • Taken for 1 to 6 months
  • April 28, 2018

For Type 2 Diabetes "Started on Trulicity 0.75 three months ago for one month, then upped to 1.5. Started out with a little nausea, but nothing horrific. Now, almost three months later, I feel like garbage every day. Belching and hiccups are awful. Constipated and nauseous, and some days actually vomiting. My ribs hurt terribly from all the retching. Am afraid to eat anything for fear it will just make me sick. Am afraid to go anywhere because the urge to throw up comes on so fast. As of today (Saturday), I refuse to take it anymore. Will see my doc on Monday to replace it with something else."

3 / 10
Was this helpful?YesNo
14 Report
  • Tip...
  • Taken for less than 1 month
  • April 15, 2018

For Type 2 Diabetes "I only gave a one because there is no zero. It's been three days since my injection of Trulicity. My head is ringing. My blood pressure is super high, and my kidney hurts. The first day, within hours, I lost my appetite, vomiting and pooping. My stomach was hurting all night. I moaned the rest of the night. Only relief was sleep. I will not take another injection. I am going herbal. Even if this works for you, you can still suffer side effects. These chemicals are not for the body. This stuff is bad. By far the worst. I am not going to be their guinea pig."

1 / 10
Was this helpful?YesNo
15 Report
  • som...
  • Taken for less than 1 month
  • June 20, 2017

For Type 2 Diabetes "I wanted to learn about side effects and effectiveness. I appreciate the posts. My experience: I am only on day 3, first shot on Sunday. I have been extremely tired, unable to sleep more than an hour at a time. I toss and turn at night. I can't hardly eat, which is good, as I tend to overeat or eat when I am not even hungry. My doctor told me to not eat sugar, rice, bread, potatoes, etc. I haven't, so I have had none of the side effects of loose bowels or vomiting, however, I am only on day 3. I have to make myself eat. I feel nauseous most of the time. I tried to choke down eggs this morning with little luck. I am hoping to get down 30+ lbs so I don't have to be on insulin as my A1C is borderline."

5 / 10
Was this helpful?YesNo
15 Report
  • Kim...
  • Taken for less than 1 month
  • August 2, 2019

For Type 2 Diabetes "This is my second time trying Trulicity, and it’s still taking me down. Within 3-4 days of injection, I’m bedridden. Can’t keep food down, throwing up and stomach pain. I’ve lost seven pounds in two weeks. Nausea, vomiting, and complete lack of appetite will do that. Constant headaches too. Trulicity is terrible. Going to quit again."

2 / 10
Was this helpful?YesNo
15 Report
  • LAB...
  • Taken for less than 1 month
  • July 22, 2018

For Type 2 Diabetes "Had my first Trulicity dose Thursday, and I have NEVER felt this bad! Headache, nausea, vomiting, diarrhea, heartburn (and I can't keep anything down or in). Sugar keeps going low because I can't keep anything down. I'm sorry, but I will not take this again! I'd rather take insulin than feel like this."

3 / 10
Was this helpful?YesNo
12 Report
  • Aja...
  • March 3, 2017

For Type 2 Diabetes "I started taking Trulicity last Monday. Once I had the first injection, I immediately felt symptoms of nausea and dizziness. I'm only in my first week, and I have called off work twice because of the diarrhea and vomiting. I do not recommend Trulicity. I will not take Trulicity next week, and I hope to not feel the way I feel now. I've lost 4 pounds, but I can't hold any food down. My blood sugar is somewhere between 146 and 120, but the way I feel, it really doesn't matter."

1 / 10
Was this helpful?YesNo
18 Report
  • Lis...
  • June 8, 2016

For Type 2 Diabetes "My PCP put me on this, and I took my first injection this past Saturday night. Woke up to horrible nausea and sulfur burps on Sunday. Still dealing with those today (Wednesday). Vomited three times at work Monday around 2, and the nausea decreased for a couple of hours afterward. However, the nausea returned with a vengeance, and I took Phenergan and went to bed early when I got home. Back to work on Tuesday but had to leave after only 3 hours after the vomiting started again. Began having abdominal pain and diarrhea as well and spent most of the day yesterday in bed, eating Phenergan as often as I could. Still sick as a dog this morning and called in for the day. I will not be taking another injection, and I pray this poison wears off soon!!"

1 / 10
Was this helpful?YesNo
18 Report
  • Reb...
  • Taken for less than 1 month
  • June 12, 2017

For Type 2 Diabetes "I am a pre-diabetic and overweight and was prescribed this to help lose some weight. In my opinion, this drug is horrible. Took my 1st and ONLY injection Thursday, come Friday night I could barely move. My stomach and sides were so sore. Saturday I slept all day, had a low-grade fever, severe stomach pains, nausea, loss of appetite, headache. Sunday I went to the ER because I got worse and couldn't take the stomach pain. The doctor said it was a reaction from this drug. He gave me fluids due to dehydration from explosive diarrhea and morphine for severe pain. Today I left work early because not only am I having horrible diarrhea, I am vomiting like crazy. Low-grade fever again. I feel so sick. I would not recommend this medication at all. Of course, you're going to drop weight from vomiting and diarrhea."

2 / 10
Was this helpful?YesNo
17 Report
  • Pja...
  • Taken for less than 1 month
  • June 29, 2018

For Type 2 Diabetes "I’ve taken Trulicity for 3 weeks. I get very sick when I eat too much food at one time. Smaller portions stopped side effects immediately. I’m forced to eat less and correctly, or there are consequences of vomiting, stomach pains, and body aches. I still struggle with this some days, and food comforts me when I am stressed. I guess it’s a mental thing. I eat less on this medication. I’ve lost 8 pounds in three weeks. I want to maintain my weight loss and learn to eat right. Overall, I am pleased, and I have started exercising."

6 / 10
Was this helpful?YesNo
12 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.