Trulicity and Loss Of Appetite: What Users Say (Page 4)

• ber...
• Taken for 1 to 6 months
• May 3, 2017

For Type 2 Diabetes "I am a 60-year-old female who also takes Lantus and Metformin. I started the 1.5 dose of Trulicity about a month ago. I had mild gastrointestinal symptoms at first: flatulence, heartburn, and burps that smell like sulfur. About 10 days ago, the side effects got much worse: abdominal cramping, explosive diarrhea, nausea, and vomiting. I had to call in sick to work twice in the last week. Sometimes I feel better, but then the symptoms hit out of nowhere. I have absolutely NO appetite and have to force myself to eat. Feels like food poisoning. This morning I had to go to the ER. They did tests, and the doc said it was due to the Trulicity and I should stop taking it. I used to be on Victoza, which worked fine, but the insurance company won't pay for it."

• Anonymous
• Taken for less than 1 month
• August 17, 2019

For Type 2 Diabetes "Took my first dose last week; I was prepared for nausea after the shot, but not for days of nausea. I was nauseated and could not stand for more than 10 minutes without having to lay back down. I started taking it on a Friday afternoon, thank goodness, because I would not have been able to go to work. I had a headache too (and I rarely have headaches). I was out of commission Saturday and Sunday; it was all I could do to go to work on Monday. Tuesday I started feeling better but had stomach pains. I did have a decreased appetite, but who doesn't when you're so nauseous? And I've lost two pounds, but I can't eat when I'm sick at my stomach. So, now it's time to take a second dose, and after reading all the comments, I don't think I want to lose another weekend."

• Ber...
• Taken for less than 1 month
• June 20, 2019

For Type 2 Diabetes "I started using Trulicity on 6/11/19; immediately I saw impressive results with my glucose numbers. I also experienced a rapid decrease in appetite. I track my calories in very closely, and I could barely get 700 calories a day for the first week. By day 5, I was vomiting with terrible stomach cramps in the early morning (5 a.m.). However, my glucose numbers remained 99-140 the entire first week. On 6/18, I took my second dose of Trulicity. The next day, I could barely function; my stomach was in so much pain. I have been nauseated just about every day since my initial intake. I haven't had a bowel movement in 13 days. And my stomach felt like a soda bottle shaken up and someone was slowly twisting off the cap. Today, I called my doctor with my side effects, and they want me off of Trulicity and back on slow-acting Lantus."

• mee...
• Taken for less than 1 month
• March 23, 2018

For Type 2 Diabetes "Started taking Trulicity March 14th (Wednesday). The next day I wasn't really hungry but went to cycle class, and I felt nausea, but after class got something to eat. Then, 40 minutes later, my stomach was hurting so bad, then I went to the restroom and felt better. The next morning I had to make myself eat breakfast (Special K), ate about 4 bites, and I didn't want any more. So my only side effects are some nausea, very, very lite abdominal pain, and really have no appetite. I have to make myself eat and drink water, and some fatigue from time to time."

• Sus...
• February 23, 2021

For Type 2 Diabetes "I have been on Trulicity for 2 weeks. Prior to this, I was on Byetta for 5 years. At this time, Byetta is no longer available where I live. While on Byetta, my A1C was 5.5, there were no side effects, and my weight dropped by 20 lbs. When I could no longer buy Byetta here for $125/month and no prescription, I was put on insulin (Lantus and Humalog). The problem was many hypoglycemic episodes and I could not get regulated. Hence Trulicity. My readings stay in the 160's. I have abdominal discomfort, lack of appetite, and constant indigestion. (And the cost is $190.00 per month!) I am not sure I can stay with this... would love to have my Byetta."

• CCp...
• December 11, 2017

For Type 2 Diabetes "The first day after the shot, I felt lethargic and so very tired. The loss of appetite is the first thing that is apparent. I am having bowel issues, but I consider the trade-off worth it. My sugar was 232 and is now between 92-158 depending on what I had for dinner the night before. Rice seems to make things bad. I have been on Trulicity for a month now and, with the help of a calorie counter (MyFitnessPal), I have lost 20 lbs and feel so much better. I did develop a bit of inflammation in the third week, but it didn't last long, and who is to say it was related to Trulicity. Overall, it's really keeping my appetite at bay, which was unheard of before. I love this drug."

• RN...
• April 26, 2018

For Type 2 Diabetes "I started taking this drug a couple of months ago. At first, it wasn’t too bad-a little nausea and decreased appetite. The more I took it, the worse the symptoms became. Severe vomiting, diarrhea, and cramping, weakness, and fatigue. At first, I thought it was just a virus, but it happened every time I took the drug. The vomiting and diarrhea have been so severe lately that I have had to miss work because of it. I will never take this drug again!"

• Gno...
• Taken for less than 1 month
• December 1, 2021

For Type 2 Diabetes "Took Trulicity on Friday. Felt like I had been winded, but nothing too bad. But the next morning, the nausea, dizziness, and loss of appetite came on strong. It's now Wednesday. I haven't kept any food down for 4 days, been violently throwing up. Stomach pains keep me up most of the night. I was started on 1.5 mg even though I am at the bottom end of pre-diabetic. Not sure whether I should continue to try and get past these side effects or call it quits. Don't think I've ever been so ill before."

• bpl...
• Taken for 1 to 6 months
• September 28, 2017

For Type 2 Diabetes "Second day after taking Trulicity, my ear turned bright red on the top, was hot to the touch, and was burning. Also, had a little headache. Called the doctor and was told to try another dose. The next week, got the red ear and burning sensation almost immediately, felt bad. At the third week and fourth weeks, had the red ears and burning down the sides of my throat. Fifth week had such a burning down the sides of the neck and throat, just could not move. Left work and covered up my head and slept. Couldn't eat. Did not take another dose. Did not have the nausea or other things I have seen listed, did have loss of appetite, didn't even want to drink anything. Has anyone else had the burning red ear tops or neck and throat?"

• Str...
• Taken for less than 1 month
• March 1, 2018

For Type 2 Diabetes "This 'medicine' has missed the point of medicine. I thought medicine was to make you feel better. Trulicity has very much the opposite effect. It makes you worse. Nausea and vomiting do not seem to be better than no nausea and vomiting. The gut pain is horrible...never had that before. The loss of appetite is horrible...food, nutrition, sustenance is good for you. How can not being able to put anything, not even water, in your stomach good for you? I fail to see the benefits. Do not take this 'medicine.' It's snake oil poison at best."

• Aj1...
• December 7, 2016

For Type 2 Diabetes "Started the injection last week on Wednesday, fine until Thursday morning, then the nausea hit! Thank goodness I work with doctors, as they gave me Zofran, which helped. Only had to take it once the rest of the week. I have felt queasy, with no appetite, lost about six pounds, and having to make myself eat. Scared to take the next one today, but my blood sugar is down, and I am losing, so I guess I will take it. Started on the low 75 dose last week and this week, then supposed to up it to 1.5?"

• Ann...
• May 18, 2017

For Type 2 Diabetes "I took my first Trulicity shot this week. By the second day, I felt horrible: severe stomach pains, fever, loss of appetite, cramps, cold belching, acid reflux. I can't imagine a medication can make you feel so terrible. I will not recommend Trulicity."

• Alm...
• July 12, 2017

For Type 2 Diabetes "Well, this is week 2 taking this, and I have every single side effect. The worst is the abdominal pain. Of course, you're losing weight with nausea and diarrhea. I have zero appetite but must eat something. I have lost 6 lbs already, but it's due to side effects. Not sure if I will continue this treatment if this abdominal pain doesn't subside."

• mbz...
• Taken for 1 to 6 months
• September 10, 2018

For Type 2 Diabetes "I was diagnosed after being found to have a fasting BS of 324 and an A1C of 12.8. I began taking Trulicity 0.75 mg injections weekly. I did initially have a loss of appetite for the first few weeks, bouts of long aching abdominal cramps, and nausea, especially later mornings when BS seemed to drop. In 4 weeks, the medication lowered my A1C to 7!!! My kidney and liver function was even near perfect. My blood sugars are staying, for the most part, 120-160, but the doctor says the A1C matters more than the blood sugars at this time. I did have horrid pain with the injection the first 3 months. I did have one vial of medication that did not inject correctly and was wasted."

• I...
• Taken for less than 1 month
• February 10, 2018

For Type 2 Diabetes "I gave myself the first shot 3 days ago, and I quickly felt nauseous, but I was able to handle it. Woke up the next morning and began to vomit. I had to miss work since I was not feeling well and felt nauseous all day. The next morning, I threw up again. The nausea is okay today, but my ribs hurt, and my stomach feels sore. I guess it is because of the vomiting. Then I went to pee, and it looks blood orange, but I could be dehydrated, so I am drinking water now. But I have no appetite, and I lost like 5 lbs these past five days. I am happy about that, but I regret testing out this medicine, it is horrible."

• A15...
• November 18, 2017

For Type 2 Diabetes "I see from reviews that this had been bad for some and good for others. For myself, it has been more good than bad. I started on 0.75 four weeks ago. I found a loss of appetite, a little nausea, some burping, and lost a few pounds. After a couple of weeks, I think I adjusted to the medicine and had no side effects, and my appetite came back. I am now on a 1.5 dose and am getting the same side effects as before. I have now lost 5 lbs. I also take 1000 mg metformin twice a day and glipizide 20 mg once a day. My blood sugar numbers have improved from an average of 240 - 300 to about 110 to 200. My A1C went from 12.7 to 10.3 in four weeks, and I am now waiting to go have it checked again in two weeks. This is the best result from any medicine I have taken."

• 75...
• Taken for less than 1 month
• September 17, 2022

For Type 2 Diabetes "Wanted to get off Jardiance because of constant yeast infection and peeing. After two doses of Trulicity, I was so sick. Nausea was mild and went away, but diarrhea started. Second dose diarrhea became worse. One night I farted and had sulfur burps for 3 hours, I had stomach ache and no appetite. Of course, most people would lose weight living like this. But not me-not a pound. Then skin on my forefingers started to peel in chunks. That’s when I called the doctor and said I am going back on Jardiance. I waited 3 weeks until this drug got out of my system and blood sugars started to creep up. Only then did I restart Jardiance, so yes it will lower your A1C, but you feel like you are dying. Now I am stuck with over $200 of meds I can’t use."

• Sar...
• Taken for less than 1 month
• July 25, 2022

For Cardiovascular Risk Reduction "Worst experience ever! Straightaway terrible nausea, bloating, and gas/burping. Complete loss of appetite - including food smell sensitivity. Then the vomiting started. Daily, repeatedly. Woke up through the night vomit. Ended up in the hospital. Tested for pancreatitis. Day 7 and still forcing myself to eat. Can barely tolerate anything. Stomach bloated. Brain fog. Will not continue."

• Rac...
• Taken for 1 to 6 months
• February 4, 2018

For Type 2 Diabetes "The first 48 hours after my injection, I burp a sulfur smell that leaves me nauseated. I also have to raise my heat in my house as I’m often cold. Some weeks I’m not hungry and wonder if the dose is the same in every injection. I’ve been taking this medicine for 5 months now, and it’s the only prescription medicine I take. I’m extremely happy with the results, as I lost weight."

• Jay...
• December 8, 2017

For Type 2 Diabetes "This is week 3 of me taking Trulicity, it started off okay, finally seeing blood sugar under 200. Loss of appetite, lost a few lbs, BUT then came the headaches, orange urine, bad stomach cramps, and now my foot has been swollen for a week. I went to the ER, they said I was fine. Could be side effects of the Trulicity and told me to check with my doctor. I was on Januvia, glipizide and never had these kinds of side effects. Metformin makes me so sick. I'm going to my doctor today to prescribe something else, as I can't deal with the Trulicity."

• BAM...
• Taken for less than 1 month
• September 6, 2021

For Type 2 Diabetes "I took 1 injection of Trulicity, 0.75 mg on August 18, 2021. Several hours later, I had a terrible headache, the back of my neck hurt, my shoulders and arms hurt too, nausea, and no appetite whatsoever. Fourteen days later, my heart rate went up, four days later, it went up again. I read that increased heart rate is a side effect of Trulicity, so I wonder how long it takes to completely clear my system? I took my one injection 18 days ago, and I read that Trulicity has a half-life of 5 days, so how many days will it take to get out of my system?"

• Ger...
• December 14, 2017

For Type 2 Diabetes "Awful heartburn, belching, headaches, nausea, and absolutely no appetite, lost over 7 lbs in 4 weeks, could not afford to lose weight. Worst medication I have ever been on. The only good thing about it was it did bring down my blood sugar levels."

• Kel...
• July 6, 2021

For Type 2 Diabetes "So I will be going on my 4th week of using Trulicity. I have had quite the experience. For the 1st 2 weeks I thought I might not be able to go through with it due to side effects of diarrhea, nausea, headache, feeling of being carsick, no appetite. Then finally it subsided. I have been taking a new high blood pressure med and metformin 750 mg 2 times a day. All started the same day so I thought maybe the combination of new pills all at once had done me in. Well, I missed a day of metformin and blood pressure meds on accident as I am not used to taking pills every day. And omg!! Diarrhea and sick since. Like my body is getting used to it all over again. I am happy with the no appetite though."

• Bet...
• Taken for less than 1 month
• May 17, 2023

"This is the second time I've tried Trulicity. The first time I stopped it because my family doctor at the time stated because I was only pre-diabetic, the benefits did not outweigh the risk. This time, however, my eGFR was highly elevated and was recommended again by my endocrinologist. I'm on my second week... I have absolutely no appetite, heartburn and indigestion are my constant companions, as well as nausea and vomiting, which seems to subside after about three to four days. I believe if I continue to take this medication, things are only going to get worse. Therefore, I will be calling my doctor and telling her that I no longer wish to take this medication."

• Kez...
• Taken for less than 1 month
• January 30, 2020

For Type 2 Diabetes "Newly diagnosed Type 2, put straight onto this drug, Trulicity. Bad side effects: nausea, headache, dizziness, no appetite, blurred vision. Getting off this, never to take it again."