Trulicity and Loss Of Appetite: What Users Say (Page 2)

• Anonymous
• Taken for less than 1 month
• June 24, 2019

For Type 2 Diabetes "On 06/16/19, I took my first injection of Trulicity, and for the first 2 days, I felt good. My sugar levels were staying between 100-130. By the morning of day 3, I was starting to feel nauseated. Then I was starting to belch up a nasty taste in my mouth, like a metal taste, and it smelled like sewage. Then I started to get very bloated and gassy. I could not have bowel movements and could not release any gas out of my stomach. My stomach felt so hard, and it was hurting me so badly. I had a very bad full feeling, and I stopped eating by that Friday morning, which was the 5th day, and I was experiencing very bad indigestion. I took Gas X and Pepcid AC, but no relief at all! I have gone 4 days with no appetite, and I’m getting concerned because of being a Type 2 diabetic. I really think this medication needs to be taken off the market. I have read too many bad reviews with people having the same symptoms. I will definitely NOT be taking this medication again or ever recommend it for anyone to take!!"

• Pig...
• Taken for less than 1 month
• October 3, 2019

For Type 2 Diabetes "I'm on day 10, so I have had two injections. My fasting numbers are really good! No gastrointestinal side effects except mild heartburn. Experienced decreased appetite and have lost 6 lbs so far. I have horrible side effects with metformin in any form or amount. I used to take Byetta with much more severe side effects. Mostly nausea."

• Uni...
• Taken for 1 to 6 months
• August 1, 2015

For Type 2 Diabetes "I have been on this medication for the last month. I had been taking up to 50 units of Novolog and 50 units of Levemir, 1000 mg of metformin, and 300 mg of Invokana. So I added Trulicity (highest dose). My side effects have been 14-pound weight loss, appetite loss, and some diarrhea. My blood sugars have been the best in 10 years...150 and below. I feel great. I have decreased my insulin to just a few injections a day. I am more than satisfied!"

• Ton...
• August 23, 2015

For Type 2 Diabetes "Been on T for about 6 weeks. No nausea, and about an 8 lb. weight loss. Morning readings sometimes in the seventies. I take 17 units of Levemir at bedtime, but morning readings have never been as good until I started on Trulicity. It replaced a daily shot of Victoza, max dose, for which I am grateful. I am awaiting my first A1c test results to see if I can finally go under 7.0 at last. A couple of notes necessary here: Not expecting drugs I take (including Januvia, Metformin, Repaglinide plus the injectables) to produce miracles. Definitely have had a loss of appetite, but I have moderated what and how much I eat, mostly vegetarian dishes and very limited alcohol and meat. Plus, been trying to walk 6000 steps/day. All working for me."

• miz...
• Taken for 1 to 2 years
• June 7, 2019

For Type 2 Diabetes "I have been on Trulicity for about 13 months. At first, I experienced nausea and loss of appetite. I lost 13 pounds within about the first 6 weeks! I took nausea medicine to help me get through the nausea symptoms. But it did help my A1C drop from 9.3 to 6.6. After several months, my symptoms subsided and I seemed to be on an even keel. My appetite returned and I gained weight back. All of a sudden, for the last 5 weeks, I have been sick as a dog! The nausea has returned, I have indigestion and belching like never before, and stomach pain. I am miserable. I am constipated, I am fatigued, and my kidney specialist tells me the Trulicity is causing my problems. I took my last injection 2 days ago, and the rest of it is going in the trash!!! No more for me."

• Nev...
• Taken for 1 to 6 months
• June 28, 2018

For Type 2 Diabetes "The first week after the shot, I felt exhausted and had no appetite whatsoever. I could only eat a few bites of each meal. The second week, I felt totally normal. Third week, less than 6 hours after taking the dose, I was vomiting and had severe stomach pains and diarrhea. I was so sick that I had to go to the emergency room. The remainder of that week, I would have terrible diarrhea after eating any carbs or fatty foods. The doctor told me to try it one more time. I waited 2 weeks to try it again because I was honestly mortified from the time before. I tried it once more and had severe stomach pains and bloating all that day. That night, I began vomiting and felt like I was going to pass out. It began to be so severe that I had to be hospitalized again. I will never take this medication again. I felt 10x worse than I did when I had the flu. I’m only 21 years old, and usually, my body is not sensitive to medications."

• Bil...
• Taken for 1 to 6 months
• December 14, 2016

For Type 2 Diabetes "I am into my 10th week. The first couple of weeks, I had massive, painful cramping for 2 days following the injection. A little bit of diarrhea. Third week onward, no issues. My glucose before ran from 180 to 250, now it is 112 to 156. I feel great. Have been able to increase my exercise due to increased energy. I have also lost my appetite and can't eat much. I have lost 3 pounds in the last 10 weeks. I take my dose every Friday in the evening."

• Yol...
• November 15, 2015

For Type 2 Diabetes "Started on the lowest dose as prescribed by my endocrinologist on a trial basis. I experienced a loss in appetite and extreme nausea, but never vomited. A two-week follow-up showed my A1C went from 8.1 to 6.0. He increased my dose. The higher dose still made me nauseous, but it increased my appetite and caused major bloating. I was losing weight, but my belly looked bigger. Experienced mild anxiety and depression. Overall, it does lower A1C, but I don't want to be nauseous the majority of the time, nor do I want to feel depressed and super bloated. I quit seven weeks in. I was all about this medication at first, but now I wouldn't recommend it."

• RHH...
• November 11, 2015

For Type 2 Diabetes "I have been on this medication for about a month now. Not as much nausea as when I was taking Bydurian, but I am exhausted, have no appetite, get sick if I eat anything fried (chicken), etc. Very anxious feeling all the time to the point of not being able to watch my grandchild, along with depression, which I think is due to feeling like crap on this medication. I have lost about ten pounds, but is it worth all this? Anyone else having these anxious feelings or malaise on this medication?"

• che...
• March 8, 2016

For Type 2 Diabetes "Not sure if it's only the medicine or the endocrinologist prescribed it wrong, but all I can say is I am sick, sick, sick every day, all day for the past 2 weeks. The second shot was 1.5. Not sure what the first one was, as it was given to me at the doctor's office. I felt nauseous the whole first week. This week, extreme nausea, acid reflux, loud burping, bloating, lack of appetite, and/or disgusted by the sight and smell of all foods. Only one good comment: my blood sugar has gone down from 140ish to 110-129, and I also decreased my Lantus units. However, I cannot function like this, so I'm stopping this med immediately."

• Scr...
• Taken for 1 to 6 months
• November 16, 2018

For Type 2 Diabetes "I had every side effect - some worse than others, but the worst of them was the appetite suppression. I ate virtually nothing for four weeks, went through ketosis, and finally into gluconeogenesis. Losing weight as a side effect is no bad thing, but not when it mimics a wasting disease. I have lost, on average, 1 lb in weight a day for the time I was on this drug. Constipation, stomach cramps, nausea, fatigue, and not wanting to eat a thing eventually drove me to seek an alternative. It did bring my blood sugar down, but the side effects have been horrendous. I'm pretty sure a carb-free diet would have had much the same effects."

• Scr...
• Taken for 1 to 6 months
• November 16, 2018

For Type 2 Diabetes "I had every side effect - some worse than others, but the worst of them was the appetite suppression. I ate virtually nothing for four weeks, went through ketosis, and finally into gluconeogenesis. Losing weight as a side effect is no bad thing, but not when it mimics a wasting disease. I have lost, on average, 1 lb in weight a day for the time I was on this drug. Constipation, stomach cramps, nausea, fatigue, and not wanting to eat a thing eventually drove me to seek an alternative. It did bring my blood sugar down, but the side effects have been horrendous. I'm pretty sure a carb-free diet would have had much the same effects."

• Lun...
• Taken for less than 1 month
• February 17, 2020

For Type 2 Diabetes "Took my first Trulicity injection this past Friday. Felt horrible ALL weekend and not able to do anything; barely got off the couch! Have terrible nausea, vomiting, and diarrhea. Lost my appetite and not keeping food down. I have also had a terrible headache since Saturday. Taking this is worse than the actual condition. Will no longer take it. I cannot work like this!"

• Den...
• December 14, 2016

For Type 2 Diabetes "I've been on this drug about four weeks now, just gave my fourth injection yesterday. First injection wasn't that bad, felt nauseated for two days, lost appetite, had to remind myself to eat, but I was fine the rest of the week, and such a remarkable improvement on my blood glucose results. Second injection was very nauseated, but no vomit on the first day. Second day, woke up at 4 a.m. feeling sick to my stomach, shaking, sweating, my BS was 130 mg/dl. Vomited like endless, then was fine again the rest of the week. Third injection, felt much better, a little nausea the first two days, then fine. I've lost 4 lbs in four weeks, my BS number averages 110's, A1C dropped from 8.4 to 7.2 in three weeks. It's a very expensive drug, but I think it's worth a try."

• Bri...
• Taken for 1 to 6 months
• January 9, 2020

For Type 2 Diabetes "Have been on Trulicity 0.75 for 5 weeks, no side effects, but did wake up this morning with a stomach ache, but could be anything. Little loss of appetite, lost a little weight. Usually check blood sugars twice a day, but starting new drug, checking it three times until I’m sure how this works. But so far, working good - numbers are down, averages are now 130 at fasting, before lunch 99, and dinner 101. Still take Metformin 500 day and night. A1C was 8.2. Sure A1C numbers will be down next DR. visit. Gave it a 9 because a little too early to give it a 10."

• Whi...
• Taken for less than 1 month
• April 10, 2018

For Type 2 Diabetes "Terrible experience. Shortly after taking on a Sunday, I was extremely fatigued. Lost all appetite the rest of the day and Monday. Constant hiccups and burping, acid reflux was so bad by Tuesday night it woke me up coughing it up. Appetite started to reappear by Wednesday, so had a smaller normal meal in the evening. Early hours of the morning, projectile vomiting and diarrhea. After reading reviews here and seeing that thyroid cancer is a risk, contacted GP. Advised to discontinue. Felt unwell and like a zombie all week. It's very worrying that there are no long-term studies of this medication in humans. It causes cancer in mice and rats. Because it hasn't been tested, it's not known if it will cause cancer in humans. So we're all guinea pigs."

• Don...
• Taken for less than 1 month
• September 25, 2019

For Type 2 Diabetes "Took first injection on Friday. Blood sugar is great. The problem is I feel like I am going to die. Tired, weak, dizzy, fever, zero appetite. I would rather have diabetes than continue with this drug. Five days now, still waiting to feel better. Also, two boils developed on my legs. Doctor visits, antibiotics, ointment. This is a nightmare."

• Bou...
• Taken for less than 1 month
• September 10, 2016

For Type 2 Diabetes "Shot easy to administer. Had nausea come and go - severe at times. Expected loss of appetite. Shortly after 4th shot, digestion came to a screeching halt. Can't eat anything solid for the last 2 days and praying the last dose wears off so I can defecate! Various anti-constipation treatments have failed. This is the worst medication reaction I've ever experienced, and I won't be taking another dose."

• Big...
• Taken for 1 to 6 months
• September 7, 2019

For Type 2 Diabetes "After the second 0.75 mg dose of Trulicity, I experienced sulfur-like burps/indigestion, explosive diarrhea, total loss of appetite, and light-headedness. I contacted my doctor and was told it was the Metformin causing these side effects, I disagreed and stopped taking the Trulicity after 1 month."

• Ell...
• Taken for less than 1 month
• August 18, 2018

"Started my first 2 injections with trial .75 dose as prescribed by my doctor for weight loss. Had absolutely NO APPETITE. Thought it was wonderful until week 2 when I took my first full 1.5 dose. One hour after taking it, I had a stroke to my right brain stem from a clot. I didn't realize it had put my heart into A-FIB. I am a nurse, I didn't see the warning on the prescribing info, but it is on the Lily website that Trulicity can cause electrical issues with your heart! The hospital neurologist had me stop it immediately. I am 49 and now on cardiac meds and blood thinners for the rest of my life. I am blessed it didn't kill me. Not worth the risk!"

• met...
• Taken for less than 1 month
• July 27, 2015

For Type 2 Diabetes "Been on this for only 4 days, and the side effects are horrible. Pulse runs constant at 115, tightness in chest, difficulty in breathing, constant belching, foggy feeling, intense stomach aches (I never got stomach aches), constant nausea, lack of appetite (that's positive), pain in my chest like my heart is being squeezed. Odd sugars have dropped, range 110 to 140, but when I have not eaten, they are at the 140 mark. 4 weeks ago, before starting medicine, I started eating proteins and vegetables only. They have not dropped. Odd. Not using this again."

• DR ...
• June 14, 2017

For Type 2 Diabetes "My first 2 weeks were awful! Nausea, constipation, extreme stomach ache, loss of appetite, and muscle spasms on my trapezoid, missed a few days of work and one emergency room visit for the muscle spasm. The third week was a whole lot better, and now I'm 2 months in, have lost 30 lbs! Little to no side effects, and feel great! Blood sugar numbers are no higher than 98, and they stay stable pretty much all day."

• DJa...
• Taken for less than 1 month
• April 14, 2019

For Type 2 Diabetes "In my experience, Trulicity is plain horrible! I've had abdominal pain and lack of appetite. What was more troublesome to me was the way my numbers started fluctuating all over the place! One minute I'm at 85, the next at 200! This was every day! Just went in to have my 3-month blood and urine draw, fasted for 36 hours, nothing but water. Got the test results back and my blood sugar was 178 and my A1C was at 7.7, up from 3 months earlier at 7.0. I will no longer be taking this rubbish."

• der...
• Taken for 1 to 6 months
• July 6, 2017

For Type 2 Diabetes "Addendum to June 13th post: My A1c is 7.2, down from 9.2 in May. That's 2 points in 2 months. Yay!!!! My Endo was very pleased. He started me on Trulicity 0.75 in May because I was having GI issues with Janumet. I've had no nausea or diarrhea with Trulicity. Only mild headache, decreased appetite, some abdominal soreness/achiness, and low blood sugars during the day. Now, I take 5-10 units of Novolog prior to meals and at times none at all depending on my blood sugar reading. My Levemir has decreased as well-I take 42 units at night vs. the previous dosage of 50 units twice daily. My weight is down 6 lbs. I recently filled a prescription for a 90-day supply of Trulicity and did not have a co-pay. Overall, I am pleased."

• Sdm...
• Taken for less than 1 month
• May 4, 2019

For Type 2 Diabetes "My A1c crept up to 7.4 after 4 years on Metformin, and the doctor suggested Trulicity in addition to staying on Metformin. After 6 straight days of Trulicity-induced nausea, cramping, diarrhea, fatigue, little appetite, leaving me weak, I honestly do not think I can handle a second week. Slight decrease in morning fasting, so I am just not sure what I’m going to do... Ugh."