Trulicity and Diarrhea: What Users Say (Page 4)

• Nev...
• Taken for 1 to 6 months
• June 28, 2018

For Type 2 Diabetes "The first week after the shot, I felt exhausted and had no appetite whatsoever. I could only eat a few bites of each meal. The second week, I felt totally normal. Third week, less than 6 hours after taking the dose, I was vomiting and had severe stomach pains and diarrhea. I was so sick that I had to go to the emergency room. The remainder of that week, I would have terrible diarrhea after eating any carbs or fatty foods. The doctor told me to try it one more time. I waited 2 weeks to try it again because I was honestly mortified from the time before. I tried it once more and had severe stomach pains and bloating all that day. That night, I began vomiting and felt like I was going to pass out. It began to be so severe that I had to be hospitalized again. I will never take this medication again. I felt 10x worse than I did when I had the flu. I’m only 21 years old, and usually, my body is not sensitive to medications."

• Nev...
• Taken for 1 to 6 months
• June 28, 2018

For Type 2 Diabetes "The first week after the shot, I felt exhausted and had no appetite whatsoever. I could only eat a few bites of each meal. The second week, I felt totally normal. Third week, less than 6 hours after taking the dose, I was vomiting and had severe stomach pains and diarrhea. I was so sick that I had to go to the emergency room. The remainder of that week, I would have terrible diarrhea after eating any carbs or fatty foods. The doctor told me to try it one more time. I waited 2 weeks to try it again because I was honestly mortified from the time before. I tried it once more and had severe stomach pains and bloating all that day. That night, I began vomiting and felt like I was going to pass out. It began to be so severe that I had to be hospitalized again. I will never take this medication again. I felt 10x worse than I did when I had the flu. I’m only 21 years old, and usually, my body is not sensitive to medications."

• Amy...
• June 19, 2017

For Type 2 Diabetes "The day after my first injection, I was so exhausted that I slept the entire day. Two days after the injection, I vomited all day. I'm currently on day 3 with extreme nausea and diarrhea. I will not do this again! This is horrible!"

• Bil...
• Taken for 1 to 6 months
• December 14, 2016

For Type 2 Diabetes "I am into my 10th week. The first couple of weeks, I had massive, painful cramping for 2 days following the injection. A little bit of diarrhea. Third week onward, no issues. My glucose before ran from 180 to 250, now it is 112 to 156. I feel great. Have been able to increase my exercise due to increased energy. I have also lost my appetite and can't eat much. I have lost 3 pounds in the last 10 weeks. I take my dose every Friday in the evening."

• Sli...
• Taken for 1 to 6 months
• April 8, 2016

For Type 2 Diabetes "I've been taking this for a month. I've found that some days it works well, I manage to cut down/out on certain foods. It's my brain that needs to adjust. There are times when I pick at naughty food in the evenings, which causes diarrhea. I'm still learning, as I've been very overweight since childhood. No extreme reaction to it, though, so onward and upwards as the weight is coming off slowly :)"

• Car...
• May 2, 2017

For Type 2 Diabetes "My mum started on Trulicity in November. She felt nauseous almost from day one, bloated, tender stomach, diarrhea, gassy. In mid-February, she went into A&E, then into intensive care with severe dehydration. On March 6th, after 4 days back home, she died from acute pancreatitis. I only found out the cause of death today but already believed Trulicity to be the underlying cause."

• mil...
• July 17, 2017

For Type 2 Diabetes "I did fine until the first shot of increased dosage. Two days after the injection, I had severe diarrhea and vomiting. I had one walk-in clinic visit for fluids. Two ER visits, with the last ending in admittance to the hospital with five more bags of fluid. I wouldn't suggest anyone take the increased dosage if the smaller dosage is working. Actually, I wouldn't recommend it to anyone."

• All...
• Taken for 1 to 6 months
• February 1, 2020

For Type 2 Diabetes "Started Trulicity June 2019. For the first 12 weeks, it was great. A1C was down, lost about 8 lbs. Then the diarrhea, bloating, gas, and belching started. I would take it on Monday, and I was sick Wednesday and Thursday. Couldn't do anything. Tracked and limited the food I was eating, but I was still getting sick. My doctor did not know what the problem was. Finally, after a scope to make sure there was not a problem with my digestive system, I went off the Trulicity in December and am now back on Metformin. The sickness subsided. Even though I've been off Trulicity for about 2 months, I still have bouts of diarrhea, bloating, gas, and belching. I'm not sure if the Metformin is reacting with the Trulicity that's still in my system."

• der...
• May 31, 2017

For Type 2 Diabetes "I've been a DM Type 2 for 15 years, and in the last 2 years taking Levemir, Novolog, and Janumet. My last A1c was 9.1. I started having abdominal upset and diarrhea from the Metformin in the Janumet, so my doctor took me off of Janumet. He started me on once weekly Trulicity (0.75 mg) 2 weeks ago. Already, I've seen significant changes in my blood sugars: 110-140 (fasting) and 85-170 (post meals). As a result, I'm taking 1/2 the dosage of Levemir and less Novolog prior to meals. I'm hoping to come off insulin. After starting Trulicity, I had some upper abdominal soreness and stomach cramping, but those symptoms have improved. I have not had any diarrhea or nausea. My appetite has decreased because I feel full all the time. So far, so good!"

• beb...
• March 9, 2016

For Type 2 Diabetes "This is my second week on Trulicity. Nausea (comes and goes), abdominal cramping, constant full feeling. Guess that's what helps you lose weight. Who wants to eat when they feel like they just ate? UUUUGH!!! Headaches all day, muscle at base of neck on left side hurts. No diarrhea, thank God (yet anyway). Just an overall not-so-good feeling. Not sure if I will stay on this med, but trying it out to see if it lowers my sugar. I can deal with nausea, but stomach pain and diarrhea, no way."

• Dia...
• Taken for less than 1 month
• May 3, 2017

For Type 2 Diabetes "A week ago, I was diagnosed with type 2 diabetes. Due to the increase of my A1c, my endo discussed several options for my diabetes. We both decided that Trulicity would be a good try, along with an increased dose of Metformin. Was on 1500 mg of Metformin a day for polycystic ovarian disease. Currently on 2000 mg a day plus the once-a-week Trulicity injection. The day I started the shot, I had an A1c of 8.6 and a glucose reading of 232. Since then, and I am through my first week, I have not had a glucose reading above 151. I have noticed quite a decrease in appetite, and I have no desire to snack. I am colder than I used to be, and there has been some mild diarrhea, but I can deal with that over the high sugar readings."

• Swe...
• January 26, 2016

For Type 2 Diabetes "First 6 weeks was on 0.5, had a little cramping, headaches, mild reflux, nausea, this usually happens on the 2nd day after the injection. My blood sugars were so excellent that my insulin pump would have low readings at night. My appetite was no longer, and I was losing weight. Then on the 7th week, the dosage went up to 1.5. Well, let's just say I ended up in the ER. My cramping was horrible, didn't get any sleep because I was projectile vomiting, diarrhea, heartburn, muscle tightening, and severe headaches. I became extremely dehydrated, so for 3 days, I was a mess. But in all, my sugars stayed regulated and would only recommend staying on the 0.5. I don't know what my A1C is yet, but blood sugar numbers are excellent. Side effects not worth it."

• Gig...
• September 26, 2019

For Type 2 Diabetes "I feel horrible when I take Trulicity, bloated gas, diarrhea, constipation, occasionally dizzy spells, body aches. I don’t think the benefits outweigh the horrible side effects for me. Speaking to my Dr about switching meds."

• Agg...
• Taken for less than 1 month
• February 11, 2020

For Type 2 Diabetes "Started Metformin (500 mg a.m. & p.m.) and Trulicity together this past October, on a Saturday, once learning I was type 2 diabetic. Within a few days, I experienced explosive diarrhea for many, many days-I couldn’t leave the house. I did not take my next week’s dose of Trulicity, and I began taking Metformin slowly-1/2 a pill a day for a week, then 1 pill a day for a week, then 1 pill a.m. & 1/2 p.m. for a week, then the full pill a.m. & p.m. That helped my body adjust to Metformin tremendously. So, still experiencing higher blood sugar readings, I tried the Trulicity 2.5 days ago (Sat p.m.). I am nauseous and have been having severe reflux-which I already take Nexium for. The Nexium isn’t working, the reflux is too severe. After reading the user experiences of Trulicity, I will not try that medication again. I could do much better with my food choices and diet-and that is where I’ll place my focus."

• Oli...
• Taken for less than 1 month
• November 20, 2016

For Type 2 Diabetes "Holy moly. I am 4 weeks into this medication, and I feel horrid! My doc told me to stick with it. First week, I vomited and felt like I had the flu for 4 days. The second injection was just a little motion sickness. The third injection, I had horrible diarrhea and nonstop vomiting. I just don't know how much more I can take. My blood sugars have been perfect, though. I just can't deal with all the vomiting."

• Lun...
• Taken for less than 1 month
• February 17, 2020

For Type 2 Diabetes "Took my first Trulicity injection this past Friday. Felt horrible ALL weekend and not able to do anything; barely got off the couch! Have terrible nausea, vomiting, and diarrhea. Lost my appetite and not keeping food down. I have also had a terrible headache since Saturday. Taking this is worse than the actual condition. Will no longer take it. I cannot work like this!"

• Rit...
• Taken for less than 1 month
• July 16, 2019

For Type 2 Diabetes "Day 1, after the first injection, I had bad diarrhea. Days 2-8, I felt worse than anything I have ever had. Severe nausea, bloating, horrible upper abdominal pain, fatigue, blurred vision, body aches. I lost 11 lbs in 8 days due to not being able to eat. I was taking everything I could for stomach relief (Pepto Bismol, Tums, Zantac, ginger root), but nothing helped at all. I swore I wouldn't take it again, but I gave it the benefit of the doubt because I don't want to go on insulin. I took it again after 10 days and only had slight diarrhea on day 2, so I have continued it. Occasionally, I still have a little nausea or slight fatigue/body ache, but I don't feel the urge to snack at all. I have not only kept off the 11 lbs but have lost 2 more. I'm only on my 3rd injection, so I'm not sure how it has affected my A1C yet."

• wil...
• Taken for 1 to 2 years
• June 24, 2017

For Type 2 Diabetes "I have been on Trulicity for 15 months now and am very happy with the results (1.5), but don't like the side effects. For the first 2 months, I was sick for 1 or 2 days after each injection, with vomiting and diarrhea. But after that, I only had the nausea and vomiting once every month or two. I do still have loose bowel movements fairly often. I have neuropathy in my feet and hands, so I am very happy with my lower A1C (last one was 4.6). My endo has lowered my preprandial Humalog and Levemir to keep my blood sugar up around 90 to 100. I was having lots of sub-50 blood sugars."

• wil...
• Taken for 1 to 2 years
• June 24, 2017

For Type 2 Diabetes "I have been on Trulicity for 15 months now and am very happy with the results (1.5), but don't like the side effects. For the first 2 months, I was sick for 1 or 2 days after each injection, with vomiting and diarrhea. But after that, I only had the nausea and vomiting once every month or two. I do still have loose bowel movements fairly often. I have neuropathy in my feet and hands, so I am very happy with my lower A1C (last one was 4.6). My endo has lowered my preprandial Humalog and Levemir to keep my blood sugar up around 90 to 100. I was having lots of sub-50 blood sugars."

• Ali...
• Taken for less than 1 month
• December 14, 2016

For Type 2 Diabetes "Glad to see I'm not alone in the side effects. I started with 0.75 for two weeks and seemed to be doing okay with some of the side effects, but tolerable enough for me to go to the next level, which was the increased dosage of 1.5. Mistake! I had severe nausea, diarrhea, and some vomiting for the whole week. I felt like I was taking an endless colonoscopy prep. On the advice of my doctor, I did not take the next injection and waited a full week to feel better. This week I restarted the lower dose again and am hoping for the best. If this remains tolerable and once my A1C has been retested again, I may only need the lower dose. Keeping my fingers crossed. I did lose a couple of pounds during the week of horror. Will keep you posted."

• MAS...
• Taken for 6 months to 1 year
• November 4, 2018

For Type 2 Diabetes "I started on Trulicity in December 2017. It has worked great. Lost 25 lbs. HbA1c dropped from 8.2 to 6.2. Side effects: tired a lot. Diarrhea or constipation comes and goes. Feel a little nauseous on the first day after the shot, but only vomited once in all these months. Last 2 weeks, I discovered a yeast infection - not sure if it is related. I am 67 years old and have been Type II since 2003. I also take Metformin ER and Jardiance. Insurance covers part of my cost. Overall, I would highly recommend."

• dan...
• March 14, 2017

For Type 2 Diabetes "First dose of .75 of Trulicity is my last. Only able to work 1 day out of 8. Doctor really downplayed the side effects. Vomiting every day, can't eat (or keep down any food), diarrhea is the consistency of water. Absolutely a hateful drug!"

• Rig...
• April 9, 2017

For Type 2 Diabetes "On week five of Trulicity. The first night I was beyond exhausted, went to bed at 7 pm, slept all night. Week 1 had every symptom and was so sick: vomiting, diarrhea, and this deep gut burping that smelled horrible. Week 2 was better, but week 3-5 are hit and miss. I have lost about ten pounds, mainly due to little to no appetite. I take my shot on Tuesday, and I vomit every Saturday. I miss about 1 day of work a week due to feeling horrible and dizzy. This drug is horrible, but my sugar with other meds is down to 7 from 9.8 in 3 months. The burping is the worst, it's like rotten eggs... so gross."

• Whi...
• Taken for less than 1 month
• April 10, 2018

For Type 2 Diabetes "Terrible experience. Shortly after taking on a Sunday, I was extremely fatigued. Lost all appetite the rest of the day and Monday. Constant hiccups and burping, acid reflux was so bad by Tuesday night it woke me up coughing it up. Appetite started to reappear by Wednesday, so had a smaller normal meal in the evening. Early hours of the morning, projectile vomiting and diarrhea. After reading reviews here and seeing that thyroid cancer is a risk, contacted GP. Advised to discontinue. Felt unwell and like a zombie all week. It's very worrying that there are no long-term studies of this medication in humans. It causes cancer in mice and rats. Because it hasn't been tested, it's not known if it will cause cancer in humans. So we're all guinea pigs."

• Big...
• Taken for 1 to 6 months
• September 7, 2019

For Type 2 Diabetes "After the second 0.75 mg dose of Trulicity, I experienced sulfur-like burps/indigestion, explosive diarrhea, total loss of appetite, and light-headedness. I contacted my doctor and was told it was the Metformin causing these side effects, I disagreed and stopped taking the Trulicity after 1 month."