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Cefuroxime and Headaches: What Users Say

Brand names: Ceftin, Zinacef

Headaches: mentioned by 9 users (5.9%)

Based on user experiences from 152 Cefuroxime reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 11.8%
bad taste 7.9%
vomiting 7.2%
nausea 6.6%
headaches 5.9%
upset stomach 5.3%
dizziness 4.6%
fever 4.6%
chills 3.9%
cough 2.6%

Reviews for Cefuroxime

Commonly mentioned side effects
  • Kam...
  • Taken for less than 1 month
  • September 28, 2019

For Urinary Tract Infection "I was diagnosed with UTI on 9/21/2019, and the doctor prescribed me two tabs of cefuroxime a day. The medication is for 5 days. The antibiotic works as expected and has some side effects. I had a severe headache for two days, and to get through it, I took a cup of cold milk with honey. On that note, I didn't have any pain during urination."

8 / 10
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16 Report
  • Eri...
  • Taken for less than 1 month
  • June 4, 2022

For Lyme Disease "Cefuroxime is very easy to take. Compared to Doxy, this is a breeze. Still have headaches, but on day 7, so we will see. Taking it for possible Lyme after a tick bite and an itchy rash, but no bullseye or anything. It just looked like a bug bite. I also have long Covid, so that is seriously complicating things. I do not know what symptoms are from what."

10 / 10
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7 Report
  • Gre...
  • Taken for less than 1 month
  • May 10, 2023

For Urinary Tract Infection "Treatment began in the ER following blood work and a CT scan. Diverticulitis was ruled out and a UTI diagnosed. Sepsis confirmed through blood work. I was administered cefuroxime intravenously and then discharged with cefuroxime axetil, 500 mg, twice a day for five days. This antibiotic treatment proved very effective for me. Within 12 hours, the severe chills I had been experiencing subsided. Within 24 hours, I experienced better urinary flow, though still a very weak stream, and less pain. After 48 hours, I felt almost normal. I was urinating much better and with much less pain. The only side effects I experienced were a mild headache and some slight mental confusion."

10 / 10
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4 Report
  • Pye...
  • August 22, 2016

For Sinusitis "I've been suffering from acute sinusitis for 13 days now. The doctor gave me antibiotics to nip it in the bud before it becomes chronic. I'm on my 6th day of cefuroxime axetil (500 mg 2 x per day), and I feel no better. In fact, my condition continues to worsen. There is more greenish-yellow mucus, I'm beginning to cough up mucus, and sinus headaches are starting. My doctor refuses to change the antibiotic because he says it can take anywhere from 1 day to over a week to work. I have to give it 3-4 more days. Truly disappointed with this medication."

1 / 10
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17 Report
  • Mar...
  • Taken for less than 1 month
  • September 19, 2020

For Upper Respiratory Tract Infection "I was prescribed cefuroxime for a swollen throat and post-nasal drip problem that I had been suffering from for more than 30 days. I was prescribed 500 mg, twice daily, for 10 days. After reading some of the other reviews, I decided to take a probiotic pill after the first pill and a probiotic yogurt after the second pill. I took the probiotics two hours after taking each pill. It worked perfectly. I had no side effects whatsoever, except for a small headache the second day. I found the large pill a little hard to swallow, so I simply split the pill in half and took each half with food. I did not find the taste of the pill as bad as others reported. After seven days, I discontinued the drug as it did not seem to solve the problem. I am certain other users may have a different outcome, so I will not give the drug a bad rating. I just wanted to report how well I tolerated the drug without side effects. Hope this helps someone else. Good luck!"

8 / 10
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6 Report

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  • Mar...
  • Taken for less than 1 month
  • November 2, 2020

For Bacterial Infection "The urgent care physician diagnosed me with a moderate case of swimmer's ear. He prescribed me the antibiotic cefuroxime, 500 mg, for a period of 7 days. After reading other reviews, I did use one probiotic pill each day along with probiotic yogurt. To make a long story short, I had no problems with my bowels. However, the drug did provide me with a constant moderate headache. Other than that, no other side effects. Unfortunately, the drug did nothing to resolve my ear infection. So, today, a different physician is going to have me try ciprofloxacin. I was hoping to avoid Cipro as it is a lot harder on the body with a bigger spectrum of side effects. Good luck to anyone else who tries cefuroxime."

5 / 10
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2 Report
  • Kid...
  • Taken for less than 1 month
  • May 2, 2021

Cefuroxime for Sinusitis "Five days of this drug, I could barely stay awake, felt sicker than when I started, headache, the runs. Calling doc in the morning for something else."

2 / 10
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3 Report
  • jus...
  • Taken for less than 1 month
  • August 15, 2020

For Bacterial Infection "My GP gave me this cefuroxime for my ear infection. On day 4, and I've had nothing but headaches and feeling sick in the stomach. I'm also getting cold chills and a temperature."

1 / 10
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2 Report
  • Car...
  • Taken for less than 1 month
  • March 18, 2021

For Sinusitis "I have had a sinus infection with headaches, ear fullness, and pressure. Was prescribed 500 mg twice a day for ten days. I am currently on my 5th day, and I'm still sick."

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.