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Azithromycin for Upper Respiratory Tract Infection User Reviews

Brand names: Zithromax, Azithromycin Dose Pack, Z-Pak

Azithromycin has an average rating of 6.7 out of 10 from a total of 63 reviews for the treatment of Upper Respiratory Tract Infection. 60% of reviewers reported a positive experience, while 29% reported a negative experience.

Azithromycin rating summary

6.7/10 average rating

63 ratings from 65 user reviews.

Compare all 559 medications used in the treatment of Upper Respiratory Tract Infection.

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Reviews for Azithromycin

  • Chuck...
  • Taken for less than 1 month
  • December 30, 2012

Azithromycin Dose Pack (azithromycin) "I am on day 2 of the 5 day dose pack. Relief from upper respiratory symptoms has been rapid and effective. 48 hrs ago I was having severe coughing fits, sneezing, painful sinus pressure, lethargy, blocked nasal passages, unable to lie down without inducing severe bouts of coughing. 36 hrs ago I took the loading dose, and 12 hrs ago the day 2 dose. My cough is all but gone, I am able to breathe normally, my voice is back nearly to normal, the sinus pressure is gone, and I have stopped taking the decongestant I was using. This afternoon I went out shopping. I have noticed no side effects, others than a mild nausea after the day 1 dose, which may or may not have been from the medicine. This is my second highly positive experience with this medicine."

10 / 10
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129 Report
  • srob
  • Taken for less than 1 month
  • November 26, 2014

"Had bad upper respiratory infection, coughing and pain, and was prescribed the 250 pack. By day two, I was 90 percent better and no side effects. Definitely a great medicine for upper respiratory infection!"

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70 Report
  • Anonymous
  • September 8, 2011

Zithromax (azithromycin) "I have been using Zithromax for the past 6 years to fight off my upper respiratory tract infections. I have tried almost everything else in the military medical inventory to win against the URI's I get yearly (every Sept/Oct Time frame) but Zithromax wins hands down every time. Does not matter during which stage of the URI you begin to take the medicine. The first or second night you will start to fight the infection hardcore and you might notice a fever develop as your body fights against the bacteria. After that its smooth sailing so you feel better by the 3rd day and completely cured by the 5th day. It is definitely a wonder drug and worth the extra money."

10 / 10
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85 Report

Frequently asked questions

  • tigge...
  • Taken for less than 1 month
  • June 25, 2015

Azithromycin Dose Pack (azithromycin) "I haven't taken an antibiotic for several years because I haven't had a bacterial infection. Over a month ago I came down with a virus but in retrospect it soon evolved into a secondary sinus infection. I respect the avoidance of antibiotics unless symptoms clearly point to bacterial infections, and I was not running a fever, and what my sinus produced did not look foul enough. However, when this didn't abate after close to 5 weeks, even my internist agreed it might be a rare low-grade bacterial infection and gave the green light to try an antibiotic. I started it the day before yesterday and by last night it was the first time in 4 1/2 weeks I got relief from the non-stop post-nasal glob driving me crazy. It couldn't have been more dramatic."

10 / 10
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61 Report
  • Speedy...
  • December 14, 2014

"Several bouts of Bronchitis and Walking Pneumonia over the years. I was born premature and had lung issues as an infant. I do not smoke. I am healthy. The Z-Pack (250 mg) works almost immediately for me. The first day I take two, then one/day for the next four days. I am on Day 2 and already am feeling better!"

10 / 10
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56 Report

Are you taking this medicine?

  • shs
  • Taken for less than 1 month
  • August 10, 2013

"I came back from the U.K. with a terrible chest cold. I spent the first week drinking tons of water and hot tea and lounging on the couch with a heating pad on my chest. I finally went to the doctor who took a chest x-ray to make sure there was no pneumonia or bronchitis. He prescribed Tussionex cough medicine which worked great on the cough and helped me sleep like a baby. After two days the cold worked its way up into my throat and ear canals and I lost my voice. Called the doctor back who prescribed azithromycin. After 1 day I was feeling much better, but still not quite myself. After 2 days I was able to function almost normally. I've taken the 3rd dose today and am hopeful that I will be even better today."

9 / 10
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60 Report
  • Nikki...
  • January 8, 2015

"Woke up the other morning in tears not able to breathe. I did two breathing treatments and still very little relief. Went to ER and was prescribed this and I kid you not by the next morning after taking the 6, I felt 100% better. I am choking on a lot of mucus but I guess that's because it's being broken up now. This is the greatest medication I have taken in a while. It truly worked wonders. My hands are very itchy but I don't even care! I can breathe!!"

10 / 10
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47 Report

More FAQ

  • JennP...
  • May 22, 2015

"I am on day 4 of the 5 day treatment and I the only thing that is happening is that I'm getting more sick by the day. I went back to the Dr. on day 3 and said that it was getting worse (can barely swallow my own saliva) and he said that it takes the full 5 days, maybe even 6, to work. This is definitely NOT the antibiotic for me. Just wanted to share in case someone else is getting this run-around. I have to get some different antibiotics because apparently I am 100% immune to this kind."

1 / 10
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44 Report
  • Funkm...
  • Taken for less than 1 month
  • September 2, 2019

Zithromax (azithromycin) "Waited 10 days to go to the doctor thinking I had bronchitis! I wish I would’ve went to the doctor sooner because I was miserable coughing my head off with phlegm, terrible headaches, fatigue, congestion, and sweats. I ended up having and upper respiratory infection and was given a z pack. After day one I felt soooo much better and was ready to go back to work. I am on day 4 and still coughing up infection, hoping that’s ends soon! Also everyday after I take the pill I get some pretty bad abdominal pain and have to run to the bathroom but only lasting about an hour. I would say the stomach ache is definitely worth it!"

9 / 10
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24 Report
  • f...
  • Taken for less than 1 month
  • October 8, 2013

"Called Dr. Because my inner ear was hurting. She sent script to pharmacy for pick up. My ear stopped hurting but then a week later I had a chest cold. Took Z-pack, after day two I am able to function and mucus is coming up out of chest. Feeling 90% now. Was feeling at 40%."

10 / 10
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42 Report
  • spark...
  • Taken for less than 1 month
  • December 24, 2015

Zithromax (azithromycin) "Upper respiratory infection Zithromax 250mg My doctor gave me a z pak 2 tabs on day 1 followed by 1 tablet the next 4 days. Total tablets 6. Zithromax is the generic drug for Azithromycin. First time prescribed. **Note I have asthma** and was feeling more fatigued and light headed. Drugs.com interaction* checker* pointed out that since I used 2 inhalers. A. Pro-Air and 2. Advair that my potasium level would be affected. A moderate interaction warning. I started drinking gatorade and began to feel better. My mom is diabetic, and gatorade makes flavored 12oz bottles that has potassium and will not affect your blood sugar."

8 / 10
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35 Report
  • Wolfman
  • May 2, 2010

Zithromax (azithromycin) "This medicine is the best. I have been using this medicine about once every year for upper respiratory tract infections. It really starts to work by day 2 and continues to work after about a week. As with any medicine the side effects with me is going to the restroom more than usual. "

10 / 10
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42 Report
  • Texas...
  • July 13, 2010

Azithromycin Dose Pack (azithromycin) "I was prescribed 250mg, 5 day dose pack of Azithromycin for upper respiratory infection. Dosing: 2 tabs 1st day, then 1 per day for 3 days. Took 2 tabs 1st day no problem.. 2nd day, 1 tab in morning before driving to family reunion. Almost immediate intermittent left upper chest painb. No other symptoms of heart attack. Chewed 2 aspirin after lunch - only slight relief. Returned home in evening and found Cardiac symptoms listed on dose pack descriptions. Discontinued taking Azithromycin and had no recurrence of chest pains 3rd day to date. Ten days later I had electrocardiogram down and results were normal."

1 / 10
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41 Report
  • Broncky...
  • Taken for less than 1 month
  • May 31, 2015

"I have just taken Day 5 dose for a worse than usual respiratory infection. Being asthmatic I need to get a jump on these things and Z Pack works well and the one pill a day makes it convenient. Abdominal cramps and diahrea are a side effect I get with all antibiotics, and I have found eating yogurt helps. The antibiotic will kill the good bacteria in your colon as well as the bad infection and it has to bereplaced."

10 / 10
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27 Report
  • CP...
  • December 3, 2015

"I have been feeling horrible for six days. Thought I had the flu, but was diagnosed with an Acute Upper Tract Infection. Had chills sweats loss of appetite. Within 6 hours of taking the 2 first day pills I began to feel better. I feel about 80% after being 30% for the last several days."

10 / 10
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26 Report
  • netmo...
  • January 9, 2016

"My first 2 uses of this drug I had no side effects. 3rd time I had moderate nausea. Pharmacist said eat yogurt. Each time within 2 days tingling in sinuses as I felt them open up, and cured by end of pills. Also symptoms of lime disease in hips was cured, puzzled my doc. Just began new round! Advise to help nausea: Keep stomach full. Graze all day, like a cow! Oatmeal with banana, whole wheat toast with avocado, peanut butter sandwich. Something every 2 hours. Big dinner with lots of vegetables. And I eat 2 containers of tasty yogurt 2 or 3 times a day. I had light nausea 1st day that lasted maybe 1 hour."

8 / 10
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25 Report
  • DC Guy
  • December 11, 2012

"I was prescribed a 250mg Z-Pak for bronchitis/upper respiratory infection (which I'm sure was viral, but whatever). I experienced horrible diarrhea starting on day 2. After 4 pills, I gave up and called my doc, who told me to discontinue use. Guess I'll add this to my list of allergies."

2 / 10
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29 Report
  • Cwolfe
  • April 7, 2011

Zithromax (azithromycin) "Zithromax was given to my daughter for upper respiratory symptoms 3 days before her flight to Fla to visit grandparents. Within the day noticed a great difference. No side effects and she has a heart condition. My lovely daughter passed her buggies on to me been fighting it for a week. Went to doctor today, gave me the same thing.... Fingers crossed."

10 / 10
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31 Report
  • Bunny
  • Taken for less than 1 month
  • March 25, 2018

Azithromycin Dose Pack (azithromycin) "Started this 250mg tabs 5 days ago, finished all today! Began it with a non productive cough! After first dose of (2 tabs), then (1) a day for 4 days. I had fever-like-symptons, tired, severe anxiety and now have finished all. Now I have been coughing up YELLOW phlegm.. Coughing has NEVER stopped!!"

1 / 10
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17 Report
  • Cityg...
  • Taken for less than 1 month
  • November 5, 2012

"A visit to the doctor resulted in a chest X-ray and blood test which confirmed an inflammation of the lungs and bacterial infection. I was given a 3-day dosage of Azithromycin for the inflammation and warned it can cause diarrhea. I was also prescribed an inhaler as a lung test showed 25% restriction. First day no side effects except for heavy drowsiness. Second day could already feel the symptoms reducing. Second day, 20 minutes after taking the meds, I got strong stomach pains (felt in the colon area not stomach) followed by heavy drowsiness. Third day I made sure to eat before the pill, which minimized the stomach pain but I got one bout of diarrhea in the evening. Day 5' symptoms have improved although I still have a runny nose and cough."

8 / 10
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26 Report
  • cough...
  • March 5, 2017

"I had this in the past with very little success for upper respiratory infections, but for some reason, still seems to be the go-to script for my PCP. Once again, I started with the flu (fever for 3 days), and it progressed to severe sinus congestion and a cough where I sounded like I was coughing up my lungs. Got this prescribed for me and after 4 1/2 days on it with very minimal relief of the sinus congestion and next to no relief for the coughing, I called PCP back (as instructed) to let them know I was not improving. They indicated that no other antibiotics were indicated and that the z-pack works for 10 days after you take the last pill. So, I'm still sitting at home, clenching my chest and hoping that something soon gives!"

2 / 10
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16 Report
  • Karen
  • Taken for less than 1 month
  • September 28, 2017

"Just finished zpack for a upper respiratory tract infection. I've gotten progressively worse through the 5 day course. On day 4 I had a temp of 103 and severe headache. I had a temp of 99 when I began the pack."

1 / 10
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15 Report
  • Cin
  • Taken for less than 1 month
  • October 30, 2018

"Finally went to the doctor after 12 days of suffering from constant nasal drip, cough, headache, body aches, toothaches, pressure in face and ears, feeling miserable and staying in bed. Pharmacist told me to take pills after a full meal. I took the first two pills 7 and a half hours ago and the change has been dramatic. I feel 75 percent better and am amazed at how quickly I went from being in misery to feeling human again. I do not like taking antibiotics but was desperate for help and this did the trick! I feel SOOO much better!"

10 / 10
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13 Report
  • jcart
  • Taken for less than 1 month
  • August 14, 2017

"I think this stuff REALLY messed up my stomach big time! I started a 5 day treatment on 7/17/17 for a respiratory infection. The stomach problems didn't happen until the last day and to this day (8/13/17) I STILL seem to be having stomach issues. After doing some internet searching for reviews, I found some that were basically horror stories from people who took this! If this stuff has such horrific side effects, why is it even prescribed and/or WHY didn't the doctor discuss possible side effects with me beforehand?! AND, on top of all of that, I'M STILL COUGHING LIKE A CRAZY PERSON!"

1 / 10
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15 Report
  • DONT...
  • Taken for less than 1 month
  • December 7, 2018

"I can't believe it has a 7.5 out of 10. I feel more sick than I've ever been after 2 doses. I called my doctor and she told me not to finish the 5 day course. She is putting me on something else but I'm afraid to take it because I've never felt this kind of pain and sickness before and now I'm afraid to take any antibiotics.It's like the stomach flu amplified 10x. And most of the "good reviews" of this drug are about how the person didn't get sick, I didn't see much about this actually fixing the condition they had. I wish I could be in the hospital right now that's how bad it is. But I don't think they'd do anything for me"

1 / 10
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12 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.