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Azelastine / fluticasone nasal and Fatigue: What Users Say

Brand names: Dymista

Fatigue: mentioned by 8 users (4.9%)

Based on user experiences from 162 Azelastine / fluticasone nasal reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 13.0%
bad taste 11.1%
drowsiness 9.3%
tiredness 8.6%
nausea 8.0%
anxiety 7.4%
fatigue 4.9%
runny nose 4.3%
sneezing 4.3%
sore throat 4.3%

Reviews for Azelastine / fluticasone nasal

Commonly mentioned side effects
  • Man...
  • October 1, 2020

For Allergic Rhinitis "The worst medication ever!!! I noticed other people shared here what I have been experiencing: fatigue, severe lack of energy, sleepiness, but it got worse when my eyes started to get dry, to look like I had just cried, and then I experienced 'sore eye'. It was awful, I could not wear my contact lenses, I cannot see properly, and not only that, now I cannot catch my breath. During this pandemic, masks are a must, and it is difficult for me to use them. I am stopping this and talking to my doctor. Thank you all for reading. M"

1 / 10
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34 Report
  • Dem...
  • Taken for less than 1 month
  • August 28, 2020

For Allergic Rhinitis "Shocking side effects: I was prescribed Dymista for dust mite allergies and used it twice a day for 2 weeks, then once a day for another 10 days. Today it ended! I have been feeling dry and sore-eyed (constantly rubbing or asked if I've been crying), and in the past 4 days, have experienced the worst fatigue and worsening exhaustion of my entire life! I've felt like I need to sleep day and night. This, coupled with stabbing pains in my head and constant nausea, I was seriously starting to think I had some real gastric or neural issues going on! Then I came here and read the damning reviews of awful side effects of exhaustion, drowsiness, and upset stomachs. I must say there is some relief knowing I'm not alone, so I urge anyone prescribed this to monitor the side effects closely. Yes, my allergies improved (hence my 2/10 rating), but not at the cost of my overall well-being! Tonight was the last night I'll put this stuff in my body."

2 / 10
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36 Report
  • TdE...
  • May 15, 2017

For Allergic Rhinitis "Do not take this spray. I experienced 2 weeks of hell. Massively increased anxiety and panic attacks, depression, blurred vision, headaches, fatigue, restlessness. I thought I was going crazy! I put it down to the anxiety and thought I was just having a relapse. Turns out, it was the steroids in the spray. 1 week off it and my eyesight is slowly returning to normal but still have the anxiety and killer sinus pain. Not recommended."

1 / 10
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57 Report
  • Mil...
  • Taken for 1 to 6 months
  • October 13, 2019

For Allergic Rhinitis "I have had allergies, sinus pain, and pressure for as long as I can remember. I've had CT scans and various conflicting recommendations from doctors. Most recently, I was put on Dymista (about 4 months now). It was initially great, as my sinus headaches were gone. I could still feel constant sinus pressure, but at least it was an improvement. However, the past 2 months, I have been feeling extremely fatigued. I had a bunch of blood tests which turned up nothing, and the doc suggested continuing the Dymista, adding in allergy pills, and taking antibiotics in case there was an infection. A few days later, I decided to check the side effects of Dymista - fatigue! Stopped using it a few days ago, went back to my old saline nasal wash, and already I feel better. My sleep has also been wonky (and continues to be so), but maybe with fewer drugs coursing around in me, that will come right too. So the moral of the story is get out a magnifying glass and read those side effects!"

5 / 10
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25 Report
  • sle...
  • Taken for less than 1 month
  • May 5, 2018

For Allergic Rhinitis "My doctor gave me a sample of Dymista. I used one spray in each nostril, and it tastes terrible. It did help with allergies, but I was exhausted, had strange dreams, was unable to drive, and had to cancel a trip. I had the worst fatigue 36 hours after taking Dymista, and that was with two nights of sleep. It made me feel drunk. It ruined my weekend. If one dose has this effect, long-term use could have terrible side effects."

1 / 10
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23 Report

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  • HCa...
  • Taken for less than 1 month
  • October 10, 2018

For Allergic Rhinitis "After suffering from chronic rhinosinusitis on and off for years, I have been prescribed Dymista and immediately, my sinuses and ears felt clearer. However, day 3 onwards, I have felt so fatigued, horrible sinus headache with sharp pains across my head, feeling congested in my ears and heavy eyes. My pharmacist did initially say that I would need to use it for 3 weeks before it really gets to work. And it's only day 6. So I am hoping it gets better soon."

5 / 10
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12 Report
  • Sar...
  • Taken for less than 1 month
  • January 5, 2023

For Allergic Rhinitis "Dymista was recommended by my local GP for sinus congestion. After a week of use, I started feeling extreme fatigue, nausea, and headaches. I literally could not move from my bed, it was horrible. I even went to the emergency room, and no one could figure it out. I started searching for reviews online and read about similar symptoms. I threw the bottle in the bin after 3 days. I've finally started to recover from the fatigue, nausea, and headaches, but I also still have sinus congestion."

1 / 10
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3 Report
  • Anonymous
  • Taken for less than 1 month
  • April 11, 2022

For Allergic Rhinitis "My prescription strength is 137 mcg/50 mcg per spray. I have used this medication twice before noon because of severe sneezing fits today and yesterday about 9 am each day. Around 12:30 pm, I have experienced fatigue, drowsiness, and sleepiness that has lasted all day for the next 5 hours. Perhaps it is best to take this medication before bedtime. I will need to stop using it since I cannot function on it during the day and seek doctors' advice for another medication prescription. Rating 5/10 because the medication helped with sneezing and watery eyes."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.