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Acetaminophen / diphenhydramine and Headaches: What Users Say

Brand names: Tylenol PM, Headache Relief PM, Pain Reliever PM, Midol PM, Percogesic Extra Strength, Headache Formula PM, Legatrin PM, Bayer Select Max Strength Night Time Pain, ConRx PM, Acetadryl, Night Time Pain, Percogesic Original Strength, Unisom PM Pain, Genapap PM, Mapap PM, Counteract PM Extra Strength, Wal-Nadol PM Extra Strength, Excedrin PM, Tylenol Sore Throat Nighttime, Pharbetol PM, Non-Aspirin PM Extra Strength Acetaminophen PM Extra Strength Robitussin Honey Severe Cough, Flu + Sore Throat CF Max Nighttime Anacin PM Aspirin Free …show all brand names

Headaches: mentioned by 3 users (4.3%)

Based on user experiences from 69 Acetaminophen / diphenhydramine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 13.0%
anxiety 7.2%
dry mouth 4.3%
headaches 4.3%
insomnia 4.3%
sleepy 4.3%

Reviews for Acetaminophen / diphenhydramine

Showing 3 reviews tagged with "headaches". Clear filters to view all 69 reviews.
Commonly mentioned side effects
  • lfs...
  • October 1, 2009

For Headache "This worked for a while, then I started getting rebound headaches. I was waking up to excruciating headaches in the mornings after taking these at night after a period of time. They can increase with intensity over time. If you find this happening to you, you need to get off of them. They are rebound headaches."

1 / 10
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  • lfs...
  • October 1, 2009

For Headache "This worked for a while, then I started getting rebound headaches. I was waking up to excruciating headaches in the mornings after taking these at night after a period of time. They can increase with intensity over time. If you find this happening to you, you need to get off of them. They are rebound headaches."

1 / 10
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33 Report
  • Lex...
  • Taken for less than 1 month
  • June 27, 2020

For Headache "I hate this stuff. I took it at around 10:30 pm, and it did not help me sleep at all. I have been tossing and turning the whole night and having the most stressful, fast dreams. I woke up completely soaked in sweat even. I also am now awake at 5 am (at least the third time I’ve woken up throughout the night), and my nose and throat are drier than the Sahara Desert. I also have a heinous headache. I cannot wait until this stuff wears off so I don’t have to feel so dry and uncomfortable anymore."

1 / 10
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13 Report

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