Acetaminophen/diphenhydramine Interactions
There are 558 drugs known to interact with acetaminophen/diphenhydramine, along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 23 are major, 520 are moderate, and 15 are minor.
- View all 558 medications that may interact with acetaminophen/diphenhydramine
- View acetaminophen/diphenhydramine alcohol/food interactions (2)
- View acetaminophen/diphenhydramine disease interactions (11)
Most frequently checked interactions
View interaction reports for acetaminophen / diphenhydramine and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Advair Diskus (fluticasone / salmeterol)
- Allegra (fexofenadine)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Calcium 600 D (calcium / vitamin d)
- Celexa (citalopram)
- Claritin (loratadine)
- CoQ10 (ubiquinone)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Iron Sulfate (ferrous sulfate)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Nasonex (mometasone nasal)
- Omega 3-6-9 Complex (omega-3 polyunsaturated fatty acids)
- Prilosec OTC (omeprazole)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Symbicort (budesonide / formoterol)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin C with Rose Hips (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Voltaren Arthritis Pain Gel (diclofenac topical)
- Xanax (alprazolam)
- Zinc (zinc sulfate)
Acetaminophen/diphenhydramine alcohol/food interactions
There are 2 alcohol/food interactions with acetaminophen / diphenhydramine.
Acetaminophen/diphenhydramine disease interactions
There are 11 disease interactions with acetaminophen / diphenhydramine which include:
- alcoholism
- liver disease
- depression
- PKU
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
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More about acetaminophen / diphenhydramine
- acetaminophen/diphenhydramine consumer information
- Compare alternatives
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- Reviews (69)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: analgesic combinations
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
