Skip to main content

Acetaminophen / diphenhydramine and Dry Mouth: What Users Say

Brand names: Tylenol PM, Percogesic Extra Strength, Headache Relief PM, Pain Reliever PM, Legatrin PM, Bayer Select Max Strength Night Time Pain, ConRx PM, Acetadryl, Night Time Pain, Percogesic Original Strength, Unisom PM Pain, Genapap PM, Mapap PM, Counteract PM Extra Strength, Midol PM, Wal-Nadol PM Extra Strength, Excedrin PM, Headache Formula PM, Tylenol Sore Throat Nighttime, Pharbetol PM Non-Aspirin PM Extra Strength Acetaminophen PM Extra Strength Robitussin Honey Severe Cough, Flu + Sore Throat CF Max Nighttime Anacin PM Aspirin Free …show all brand names

Dry mouth: mentioned by 3 users (4.3%)

Based on user experiences from 69 Acetaminophen / diphenhydramine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 13.0%
anxiety 7.2%
dry mouth 4.3%
headaches 4.3%
insomnia 4.3%
sleepy 4.3%

Reviews for Acetaminophen / diphenhydramine

Commonly mentioned side effects
  • Aun...
  • Taken for less than 1 month
  • January 5, 2017

For Insomnia "I will never take this again. Woke with such a dry mouth I could barely swallow, and a need to use my inhaler. This is NOT a usual thing for me. Reading today, I see that anyone with asthma, etc., should not use this. I would echo that. I did sleep but still feel unwell and glad I only took TWO."

1 / 10
Was this helpful?YesNo
33 Report
  • Anonymous
  • November 11, 2008

For Pain "I had a very painful tooth abscess that was not relieved with the popular OTC medicines. A pharmacy technician recommended Percogesic, and I felt relief within 30 minutes. Pain relief lasted longer as well, so I had to take it less often. The only negative was a minor side effect: dry mouth."

9 / 10
Was this helpful?YesNo
20 Report
  • emi...
  • Taken for 1 to 6 months
  • June 18, 2024

For Insomnia "This medication definitely works, but it has its setbacks. I took this one night for my period cramps and I hadn't slept in about 2 days. I instantly got about almost 2 days of rest about 20 minutes after. My mom thought I had stopped breathing after a while. I woke up with the driest throat and, for some reason, a nosebleed. Something that has been irking me about this medication is the wacky and vivid dreams. My mother also has sleep problems, so she decided to take one with me last night. We both experienced vivid and disturbing dreams with the same contents within the dream. It was very trippy to hear me and my mom dreamed about being in the same place when we went to discuss how wack our nights were. Overall, this is a pretty good medication. I would not recommend it if you have asthma or have mental health issues, it will manifest in your waking life physically and emotionally."

8 / 10
Was this helpful?YesNo
0 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.