Tymlos and Increased Heart Rate: What Users Say

• Bro...
• Taken for less than 1 month
• July 27, 2020

For Osteoporosis "I have had 5 compression fractures and 1 broken rib since 51. I'm now 55. My osteoporosis is from prednisone. I was tall at 5'9, now I am 5'4 and my organs are being crushed. I have a hunchback from repeated compression fractures. My neck is like 4 inches forward. I've lost most of my mobility. Can barely get out of a chair or bed. I can't garden anymore or do chores. No choice but to take big pharma poisons again. Taking Tymlos for 5 days now. Had no side effects until night 4, so I take it at night. I inject it into the fatty part of my thigh. On day 4, could not sleep a wink. Heart racing, whole body neuropathy, stomach pains, gas, heartburn, dizziness, leg pain. Oh joy, now this for 18 months. It better grow bone. I've read that if you get a compression fracture, you should get a kyphoplasty to stabilize the fracture, regain vertebral height, and get out of pain to avoid a hunchback. The medical field and big pharma aren't here to help, just to live in a nightmare that I cannot awake from."

• con...
• Taken for 1 to 2 years
• June 21, 2023

For Osteoporosis "I used Tymlos from Mar 22 to Feb 23. From the first injection, I experienced a rapid heart rate, dull aching in my mid-back kidney area, frequent urination, and some dizziness. I used it before bed due to the side effects. If I got up at night, I was often disoriented. The injections also sometimes caused bruising and pain. After 2 months, I began using it every other day due to the side effects, even though these were primarily at night. But I was really tired due to getting up at night to use the bathroom. I was optimistic about this drug as it is designed to grow bone, rather than just stop bone loss like biophosphonates, and I was willing to continue treatment for another year. Super disappointed with my DEXA bone scan results and stopped Tymlos due to essentially zero benefits: Hip: -2.9. Prior -2.8, slight decrease; Femoral neck: -3.4. Prior -2.9, major decrease; Lumbar spine: -2.2. Prior -2.2, no change. For me, Tymlos was not effective. Blessings on the journey toward stronger bones."

• JPa...
• Taken for less than 1 month
• July 1, 2020

For Osteoporosis "After the 1st injection, I had back and leg pain, headache, and heart pounding. The headache lasted about 20 hours along with an ill feeling. The next 2 injections, the back and leg pain were much less, but still the headache and slightly ill feeling. Now 8 days in, just slight pain and occasional heart pounding, but only for a short period of time."

• Bec...
• February 28, 2020

For Osteoporosis "I have been on Tymlos for a month and a half. The only side effect I’ve noticed is that after some injections my heart races for a bit. Not every time. Sometimes upper stomach pain but rarely. I really hope it makes my bones stronger. I’m willing to stay with this for eighteen months if it builds my bones."

• Cin...
• Taken for 1 to 2 years
• May 1, 2022

For Osteoporosis "I am just finishing 2 years of Tymlos injections! I had a recent bone density test, and I have gone from osteoporosis level to osteopenia. I haven't met with my MD yet, but from what I can tell in the report, I have had a 19.1% increase in bone mineral density of the lumbar spine compared to the baseline exam. I have definitely experienced side effects with this drug, but it has been manageable. One of the effects for me, which no one else has complained of, is loss of appetite. I can't wait to be done to see if it returns. My MD doesn't believe it is from the drug, but the only way to know is to stop it and see if it improves. We almost considered this halfway through taking the drug, but I decided I just didn't want to interrupt the process. I also do get a pounding heartbeat/racing heart after I take it, and I do have waves of nausea during the day from time to time. Now I have to try to maintain the density increase. Next drug is Reclast."

• Ace...
• Taken for 1 to 6 months
• November 27, 2019

"I've been on this Tymlos for 5 weeks to help with nonunion of bone. Sometimes headaches after injection, always racing heart for about 5 minutes. Extreme fatigue is the worst side effect, but bone is healing, so I'll continue."

• NAa...
• Taken for 1 to 6 months
• January 1, 2021

For Osteoporosis "Just started second Tymlos pen for osteoporosis. Side effects after injection (which start 15 min or so after) lasted 3.5-4.0 hours initially, down to 15-20 minutes now. Initial side effects: 'Drugged-like feeling' (lightheaded, dizzy, brain fog, out of it), fatigue, heart pounding. Other side effects that linger daily: initial severe bone pain, which has slowly decreased, vertigo, which is still present, fatigue, weight gain, brain fog. Due to my career and safety role, I have been out of work on STD, due to the above side effects. As they are lessening, they are still present, which may cause me to end use of this drug."

• Ela...
• Taken for 1 to 6 months
• March 23, 2022

For Osteoporosis "I took Tymlos for almost 3 months. Racing heart, palpitations, being winded, and fatigue were my most severe symptoms. I am told these symptoms should have subsided in 7 or 8 hours after an injection, but that did not happen in my case. These symptoms, especially the palpitations, persisted off and on 24/7 and are still with me even though I've been off the medication for 2 weeks. So now I have to have a cardiac workup to make sure there is no damage to my heart, and I guess try to pinpoint what is happening. I did not have heart problems/issues before I started this medication. Right now, my heart is my main concern before I start to address my osteoporosis. I feel like I traded one problem for two."

• Jan...
• Taken for 1 to 6 months
• October 14, 2021

For Osteoporosis "I have been on Tymlos for two months. I immediately had a drop in my blood pressure. I then had pressure behind my eyes and was off Tymlos for two weeks. I restarted but found that my blood pressure still dropped, and I had a racing heart rate as well as insomnia. After being off of it again for two days, I have felt lightheaded, and my pulse slowed to what was not normal for me, a drop of 10 to 15 beats per minute. I have come to the conclusion that the risks and side effects are not worth it. As I have dental issues, I cannot take other medications. Forteo is the only other alternative, and it is the same class of medication and has similar or maybe more side effects."

• owe...
• Taken for less than 1 month
• July 3, 2022

For Osteoporosis "Not good. Not good at all. I finally overcame the terror of self-injection, and now I'm dealing with awful side effects: within 20 min, my heart starts to race, and that goes on for hours. I have increased pain in my spine and joints. I feel like I have the flu for about 4-5 hours a day, every day, within an hour of taking Tymlos. Jittery, achy, and generally miserable. Now I'm reading that as soon as I stop taking this drug, my bones are back to screwed anyway, so I'm considering dropping this drug for good."

• Anonymous
• Taken for 1 to 6 months
• June 24, 2023

For Osteoporosis "I’m two weeks into my second pen. The side effects have been surprisingly mild. Noticed an increased heart rate for a bit, and lately, foot and leg cramps becoming a thing. Completely manageable and worth it if it helps with a severe osteoporosis diagnosis. Injections are going well. My rheumatologist told me I can also inject it into my thigh."

• Bel...
• Taken for less than 1 month
• November 1, 2022

For Osteoporosis "I am two weeks into my Tymlos injections. Side effects have included palpitations, increased heart rate, nausea, and fatigue. The fatigue has been the hardest part so far. But I am in my early 30s and have sustained 20+ non-traumatic fractures, so I feel that this is my only option at this point. I am hopeful to see what my next DEXA looks like."

• Anonymous
• Taken for 1 to 6 months
• August 8, 2021

For Osteoporosis "I was on Tymlos for 3 months with the normal heart racing, heavy chest side effects, but the side effect that made me discontinue the drug was I woke up one morning after taking it for 3 months with severe back pain that I had not experienced before. The pain has continued for 2 months now. I have had some confirmed back problems for the last 5 years, but after much physical therapy and daily exercise, I have been pain-free for at least 3 years, and then this suddenly happened basically while I was sleeping. I had an MRI done, and my back condition had not worsened on MRI, so my spine doctor and endocrinologist both said to quit Tymlos. I am getting ready to start on Evenity. I hope I have better luck with that."

• Goa...
• Taken for less than 1 month
• September 11, 2021

For Osteoporosis "Just started. Full dose 2nd day. Immediately after injection, intense lower back pain. Followed by racing heart, followed by headache. Can't imagine keeping this up. Haven't decided if I will skip a day or cut the dose in half or both, but if I can't get these issues to resolve, then I will be done with Tymlos."

• 63y...
• Taken for 1 to 6 months
• January 29, 2022

For Osteoporosis "Two months on Tymlos, switching to Forteo soon. Within 10 minutes of injecting Tymlos (before bed), heart rate increases about 25 bpm. Heart rate goes back down within 30 minutes or less. Only other symptom is my cheeks have gotten very red and warm. So much so, that friends and family comment. Hope these two things go away when I start Forteo."