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Generic Name: rocuronium (roe-kyoor-OH-nee-um)
Brand Name: Zemuron

Rocuronium is used for:

Relaxing muscles during surgery and mechanical breathing.

Rocuronium is a nondepolarizing neuromuscular blocker. It works by blocking nerve impulses to the muscles, resulting in temporary muscle paralysis.

Do NOT use rocuronium if:

  • you are allergic to any ingredient in rocuronium

Contact your doctor or health care provider right away if any of these apply to you.

Before using rocuronium:

Some medical conditions may interact with rocuronium. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have liver or kidney problems, an acid-base imbalance, an electrolyte disturbance, Lambert-Eaton syndrome, myasthenia gravis, cachexia (weight loss), high blood pressure, or heart problems, or you are debilitated

Some MEDICINES MAY INTERACT with rocuronium. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Aminoglycosides (eg, gentamicin), clindamycin, cyclosporine, general inhalation anesthetics (eg, halothane), ketamine, lithium, local anesthetics (eg, lidocaine), magnesium salts, polypeptide antibiotic (eg, polymyxin B), procainamide, quinidine, quinine derivatives (eg, quinine), thiazide diuretics (eg, hydrochlorothiazide), trimethaphan, or verapamil because the actions of rocuronium may be increased, causing severe muscle relaxation progressing to paralysis and breathing problems
  • Carbamazepine, hydantoins (eg, phenytoin), theophyllines, or thiopurines (eg, azathioprine) because the effectiveness of rocuronium may be decreased

This may not be a complete list of all interactions that may occur. Ask your health care provider if rocuronium may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use rocuronium:

Use rocuronium as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Rocuronium is usually administered as an injection at your doctor's office, hospital, or clinic. Ask your doctor or pharmacist any questions you may have about rocuronium.
  • If you miss a dose of rocuronium, contact your doctor immediately.

Ask your health care provider any questions you may have about how to use rocuronium.

Important safety information:

  • Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to rocuronium. Using rocuronium alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
  • Use rocuronium with caution in the ELDERLY because they may be more sensitive to its effects.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using rocuronium during pregnancy. If you are or will be breast-feeding while you are using rocuronium, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of rocuronium:

All medicines may cause side effects, but many people have no, or minor, side effects. When used in small doses, no COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fast or irregular heartbeat.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of rocuronium:

Rocuronium is usually handled and stored by a health care provider. If you are using rocuronium at home, store rocuronium as directed by your pharmacist or health care provider. Keep rocuronium out of the reach of children and away from pets.

General information:

  • If you have any questions about rocuronium, please talk with your doctor, pharmacist, or other health care provider.
  • Rocuronium is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about rocuronium. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Review Date: June 6, 2017

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.