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Rocuronium Side Effects

For the Consumer

Applies to rocuronium: intravenous solution

Along with its needed effects, rocuronium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking rocuronium:

Rare

  • Cough
  • difficulty with breathing
  • dizziness
  • fainting
  • fast, slow, or irregular heartbeat
  • noisy breathing
  • swelling at the injection site
  • tightness in the chest

Incidence Not Known

  • Difficulty with swallowing
  • hives, itching, or skin rash
  • muscular pain, tenderness, wasting, or weakness
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to rocuronium: intravenous solution

Cardiovascular

Uncommon (0.1% to 1%): Arrhythmia, abnormal electrocardiogram, tachycardia

Rare (0.01% to 0.1%): Hypotension, hypertension

Very rare (less than 0.01%): Circulatory collapse and shock, flushing[Ref]

Dermatologic

Rare (0.01% to 0.1%): Injection site edema, pruritus

Very rare (less than 0.01%): Angioneurotic edema, urticaria, rash, erythematous rash[Ref]

Gastrointestinal

Uncommon (0.1% to 1%): Nausea, vomiting[Ref]

Hypersensitivity

Very rare (less than 0.01%): Hypersensitivity, anaphylactic reaction, anaphylactoid reaction, anaphylactic shock, anaphylactoid shock[Ref]

Respiratory

Uncommon (0.1% to 1%): Asthma (bronchospasm, wheezing, or rhonchi), hiccup

Very rare (less than 0.01%): Bronchospasm

Postmarketing reports: Increased pulmonary vascular resistance[Ref]

Local

Rare (less than 0.1%): Injection site pain, injection site reaction[Ref]

Musculoskeletal

Rare (less than 0.1%): Prolonged neuromuscular block

Very rare (less than 0.01%): Muscular weakness

Frequency not reported: Residual paralysis, myopathy[Ref]

Nervous system

Very rare (less than 0.01%): Flaccid paralysis[Ref]

Other

Uncommon (0.1% to 1%): Drug ineffective, drug effect/therapeutic response decreased, drug effect/therapeutic response increased

Frequency not reported: Malignant hyperthermia[Ref]

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Zemuron (rocuronium)." Organon, West Orange, NJ.

3. Pharmaceutical Society of Australia "APPGuide online. Australian prescription products guide online. Available from: URL: http://www.appco.com.au/appguide/default.asp." ([2006]):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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