Rocuronium Side Effects

Medically reviewed by Drugs.com. Last updated on Nov 2, 2024.

Applies to rocuronium: intravenous solution.

Precautions

It is very important that your doctor check you or your child closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects.

This medicine may cause a serious allergic reaction called anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Call your doctor right away if you or your child have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.

Myopathy may occur while using this medicine for a long period of time in intensive care unit (ICU). It may also occur if this medicine is used together with a steroid medicine. Tell your doctor right away if you or your child have extreme or ongoing muscle weakness while using this medicine.

Tell your doctor right away if you or your child have pale skin, pain, or redness at the injection site while using this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of rocuronium

Along with its needed effects, rocuronium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking rocuronium:

For healthcare professionals

Applies to rocuronium: intravenous solution.

Cardiovascular adverse events

• Uncommon (0.1% to 1%): Arrhythmia, abnormal electrocardiogram, tachycardia
• Rare (0.01% to 0.1%): Hypotension, hypertension
• Very rare (less than 0.01%): Circulatory collapse and shock, flushing^[Ref]

Dermatologic

• Rare (0.01% to 0.1%): Injection site edema, pruritus
• Very rare (less than 0.01%): Angioneurotic edema, urticaria, rash, erythematous rash^[Ref]

Gastrointestinal

• Uncommon (0.1% to 1%): Nausea, vomiting^[Ref]

Hypersensitivity

• Very rare (less than 0.01%): Hypersensitivity, anaphylactic reaction, anaphylactoid reaction, anaphylactic shock, anaphylactoid shock^[Ref]

Respiratory

• Uncommon (0.1% to 1%): Asthma (bronchospasm, wheezing, or rhonchi), hiccup
• Very rare (less than 0.01%): Bronchospasm
• Postmarketing reports: Increased pulmonary vascular resistance^[Ref]

Local

• Rare (less than 0.1%): Injection site pain, injection site reaction^[Ref]

Musculoskeletal

• Rare (less than 0.1%): Prolonged neuromuscular block
• Very rare (less than 0.01%): Muscular weakness
• Frequency not reported: Residual paralysis, myopathy^[Ref]

Nervous system

• Very rare (less than 0.01%): Flaccid paralysis^[Ref]

Other

• Uncommon (0.1% to 1%): Drug ineffective, drug effect/therapeutic response decreased, drug effect/therapeutic response increased
• Frequency not reported: Malignant hyperthermia^[Ref]

See also:

Further information

Rocuronium side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer