Generic Name: Alirocumab (al i ROK ue mab)
Brand Name: Praluent
Medically reviewed on May 2, 2018.
Uses of Praluent:
- It is used to lower cholesterol.
- It is used in some people with hard arteries in the heart.
What do I need to tell my doctor BEFORE I take Praluent?
- If you have an allergy to Praluent (alirocumab) or any part of Praluent (alirocumab).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Praluent (alirocumab) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Praluent?
- Tell all of your health care providers that you take Praluent (alirocumab). This includes your doctors, nurses, pharmacists, and dentists.
- Follow the diet and workout plan that your doctor told you about.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Allergic reactions have happened with Praluent (alirocumab). Sometimes, these have been very bad and people have had to go to the hospital. Talk with the doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Praluent (alirocumab) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Praluent) best taken?
Use Praluent (alirocumab) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into the fatty part of the skin on the top of the thigh, belly area, or upper arm.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Follow how to use as you have been told by the doctor or read the package insert.
- Before giving the shot, let it come to room temperature. Do not heat Praluent (alirocumab).
- Move site where you give the shot each time.
- If your dose is more than 1 injection, give the injections into 2 different places.
- Do not shake.
- Do not use Praluent (alirocumab) if it has been dropped or if it is broken.
- Do not give into the same place as another shot.
- Do not give into skin that is irritated, bruised, red, infected, or scarred.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
If you take Praluent (alirocumab) every 2 weeks:
- Take a missed dose as soon as you think about it.
- If it has been 7 days or more since the missed dose, skip the missed dose and go back to your normal time.
If you take Praluent (alirocumab) every 4 weeks:
- Take a missed dose as soon as you think about it.
- If it has been 7 days or more since the missed dose, take a missed dose and start a new schedule based on when the dose is given.
For all uses of Praluent (alirocumab):
- Do not take 2 doses at the same time or extra doses.
- If you are not sure what to do if you miss a dose, call your doctor.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
What are some other side effects of Praluent?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Nose or throat irritation.
- Redness or swelling where the shot is given.
- Itching where the shot is given.
- Pain where the shot was given.
- Flu-like signs.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Praluent?
- Store in a refrigerator. Do not freeze.
- Store in the carton to protect from light.
- If needed, you may store at room temperature for up to 30 days. If stored at room temperature and not used within 30 days, throw Praluent (alirocumab) away.
- Do not put Praluent (alirocumab) back in the refrigerator after it has been stored at room temperature.
- Protect from heat and sunlight.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Praluent (alirocumab), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Praluent (alirocumab)
- Praluent Side Effects
- During Pregnancy
- Dosage Information
- Support Group
- Pricing & Coupons
- 39 Reviews – Add your own review/rating
- Drug class: PCSK9 inhibitors