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Orphenadrine, Aspirin, and Caffeine

Generic Name: Orphenadrine, Aspirin, and Caffeine (or FEN a dreen, AS pir in, & KAF een)

Medically reviewed on September 5, 2018

Uses of Orphenadrine, Aspirin, and Caffeine:

  • It is used to calm muscles.

What do I need to tell my doctor BEFORE I take Orphenadrine, Aspirin, and Caffeine?

  • If you have an allergy to orphenadrine, aspirin, caffeine, or any other part of orphenadrine, aspirin, and caffeine.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Enlarged prostate gland, glaucoma, heart spasms, bowel block, myasthenia gravis, ulcer disease, or trouble passing urine.
  • If you have trouble swallowing.
  • If you are more than 24 weeks pregnant.

This is not a list of all drugs or health problems that interact with orphenadrine, aspirin, and caffeine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take orphenadrine, aspirin, and caffeine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Orphenadrine, Aspirin, and Caffeine?

  • Tell all of your health care providers that you take orphenadrine, aspirin, and caffeine. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert until you see how orphenadrine, aspirin, and caffeine affects you.
  • You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
  • Have your blood work checked if you are on orphenadrine, aspirin, and caffeine for a long time. Talk with your doctor.
  • Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
  • Limit your use of caffeine (for example, tea, coffee, cola) and chocolate. Use with orphenadrine, aspirin, and caffeine may cause nervousness, shakiness, and a fast heartbeat.
  • This medicine is used with rest, PT (physical therapy), pain drugs, and other therapies.
  • If you are 65 or older, use orphenadrine, aspirin, and caffeine with care. You could have more side effects.
  • Do not give to children and teenagers who have or are getting better from flu signs, chickenpox, or other viral infections due to the chance of Reye's syndrome. Reye's syndrome causes very bad problems to the brain and liver.
  • Do not give to a child younger than 12 years of age.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using orphenadrine, aspirin, and caffeine while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Orphenadrine, Aspirin, and Caffeine) best taken?

Use orphenadrine, aspirin, and caffeine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with or without food. Take with food if it causes an upset stomach.

What do I do if I miss a dose?

  • If you take orphenadrine, aspirin, and caffeine on a regular basis, take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • Many times orphenadrine, aspirin, and caffeine is taken on an as needed basis. Do not take more often than told by the doctor.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Feeling confused.
  • Anxiety.
  • Shakiness.
  • Very nervous and excitable.
  • Hallucinations (seeing or hearing things that are not there).
  • Ringing in ears.
  • Any unexplained bruising or bleeding.
  • Feeling very tired or weak.
  • Black, tarry, or bloody stools.
  • Throwing up blood or throw up that looks like coffee grounds.
  • A fast heartbeat.
  • A heartbeat that does not feel normal.
  • Trouble passing urine.
  • Change in eyesight.
  • Very bad dizziness or passing out.

What are some other side effects of Orphenadrine, Aspirin, and Caffeine?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Feeling sleepy.
  • Dizziness.
  • Upset stomach or throwing up.
  • Dry mouth.
  • Headache.
  • Hard stools (constipation).
  • Feeling tired or weak.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Orphenadrine, Aspirin, and Caffeine?

  • Store at room temperature.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about orphenadrine, aspirin, and caffeine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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