Dexilant delayed-release capsulesPronunciation
Generic Name: dexlansoprazole (DEX-lan-SOE-pra-zole)
Brand Name: Dexilant
Dexilant delayed-release capsules are used for:
Healing and maintaining healing of irritation of the esophagus. It is also used to treat symptoms of gastroesophageal reflux disease (GERD) (eg, heartburn). It may also be used for other conditions as determined by your doctor.
Dexilant delayed-release capsules are a proton pump inhibitor (PPI). It works by decreasing the amount of acid produced in the stomach.
Do NOT use Dexilant delayed-release capsules if:
- you are allergic to any ingredient in Dexilant delayed-release capsules
- you are taking atazanavir, dasatinib, or rilpivirine
Contact your doctor or health care provider right away if any of these apply to you.
Before using Dexilant delayed-release capsules:
Some medical conditions may interact with Dexilant delayed-release capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have low blood potassium or magnesium levels, low blood vitamin B12 levels or vitamin B12 deficiency, liver problems, or stomach or bowel cancer
- if you have osteoporosis (weak bones), a family history of osteoporosis, or other risk factors of osteoporosis (eg, smoking, poor nutrition)
Some MEDICINES MAY INTERACT with Dexilant delayed-release capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood magnesium levels may be increased
- Anticoagulants (eg, warfarin), digoxin, methotrexate, saquinavir, or tacrolimus because the risk of their side effects may be increased by Dexilant delayed-release capsules
- Ampicillin, atazanavir, bosutinib, clopidogrel, dasatinib, erlotinib, indinavir, iron, itraconazole, ketoconazole, mycophenolate, nelfinavir, nilotinib, posaconazole, rilpivirine, or sorafenib because their effectiveness may be decreased by Dexilant delayed-release capsules
This may not be a complete list of all interactions that may occur. Ask your health care provider if Dexilant delayed-release capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Dexilant delayed-release capsules:
Use Dexilant delayed-release capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Dexilant delayed-release capsules comes with an extra patient information sheet called a Medication Guide. It also comes with instructions for use. Read them carefully. Read them again each time you get Dexilant delayed-release capsules refilled.
- Take Dexilant delayed-release capsules by mouth with or without food.
- Swallow Dexilant delayed-release capsules whole. Do not break, crush, or chew before swallowing. If you cannot swallow the capsule whole, you may open it and sprinkle the contents over 1 tablespoon (15 mL) of applesauce. Swallow the entire mixture right away. Do not crush or chew the medicine before swallowing. Do not store the mixture for future use. Read the instructions for use for more information.
- You may also open the capsule and sprinkle the contents into 20 mL of water. Use an oral syringe to draw up the mixture. Swirl the mixture and swallow right away. Do not store the mixture for future use. Refill the syringe with water and take to be sure you have taken all the medicine. Follow the instructions for use in the extra patient leaflet.
- If the patient is taking Dexilant delayed-release capsules through a nasogastric tube, follow the instructions for use in the extra patient leaflet.
- Continue to take Dexilant delayed-release capsules even if you feel well. Do not miss any doses.
- If you miss a dose of Dexilant delayed-release capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Dexilant delayed-release capsules.
Important safety information:
- Contact your doctor if you have any symptoms of a bleeding ulcer, such as black, tarry stools or vomit that looks like coffee grounds; or if you experience throat pain, chest pain, severe stomach pain, or trouble swallowing.
- Do NOT change your dose, stop taking Dexilant delayed-release capsules, or take Dexilant delayed-release capsules for longer than prescribed without checking with your doctor.
- Dexilant delayed-release capsules may increase the risk of a serious form of diarrhea. Contact your doctor right away if stomach pain or cramps, severe or persistent diarrhea, or bloody or watery stools occur. Discuss any questions or concerns with your doctor.
- Dexilant delayed-release capsules may increase the risk of hip, wrist, and spine fractures in patients with weak bones (osteoporosis). The risk may be greater if you use Dexilant delayed-release capsules in high doses or for longer than a year, or if you are older than 50 years old. Contact your doctor if you have any questions about this information.
- Low blood magnesium levels have been reported rarely in patients taking PPIs for at least 3 months. In most cases, this effect was seen after a year of treatment. If you will be taking Dexilant delayed-release capsules for a long time or if you take certain other medicines (eg, digoxin, diuretics), your doctor may perform lab tests to check for low blood magnesium levels. Seek medical attention right away if you experience symptoms of low blood magnesium levels (eg, dizziness; fast or irregular heartbeat; involuntary muscle movements; jitteriness or tremors; muscle aches, cramps, pain, spasms, or weakness; seizures).
- Long-term treatment (eg, longer than 3 years) with medicines like this one has rarely caused low vitamin B12 levels. Discuss any questions or concerns with your doctor.
- Check with your doctor to see whether you should take a calcium and vitamin D supplement while you use Dexilant delayed-release capsules.
- Use Dexilant delayed-release capsules with caution in the ELDERLY; they may be more sensitive to its effects, especially hip, wrist, and spine fractures.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Dexilant delayed-release capsules while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking Dexilant delayed-release capsules.
Possible side effects of Dexilant delayed-release capsules:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Gas; mild diarrhea or stomach pain; nausea; symptoms of upper respiratory tract infection (eg, cough, runny or stuffy nose, sneezing); vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest or throat; swelling of the mouth, face, lips, or tongue; unusual hoarseness); bloody or watery stools; bone pain; calf or leg pain, swelling, redness, or tenderness; chest, jaw, or arm pain; depression; fainting; fast, slow, or irregular heartbeat; fever, chills, or sore throat; joint pain, tenderness, swelling, or warmth; red, swollen, blistered, or peeling skin; seizures; severe or persistent diarrhea or stomach pain; severe or persistent nausea or vomiting; shortness of breath; stomach cramps; sudden, severe nausea or vomiting; symptoms of kidney problems (eg, not able to pass urine, change in the amount of urine produced, blood in the urine, a big weight gain); symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, unusual nausea, yellowing of the skin or eyes); unexplained weight loss; unusual sweating; unusual tiredness or weakness.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of Dexilant delayed-release capsules:
Store Dexilant delayed-release capsules at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dexilant delayed-release capsules out of the reach of children and away from pets.
- If you have any questions about Dexilant delayed-release capsules, please talk with your doctor, pharmacist, or other health care provider.
- Dexilant delayed-release capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Dexilant delayed-release capsules or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Dexilant delayed-release capsules. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Dexilant delayed-release capsules. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Dexilant delayed-release capsules.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Dexilant (dexlansoprazole)
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- Drug class: proton pump inhibitors