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Medications for Multiple Sclerosis

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
monomethyl fumarate 2.0 1 review for monomethyl fumarate to treat Multiple Sclerosis
Rx N
Generic name:
monomethyl fumarate systemic
Brand name:
Bafiertam
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
ponesimod Rate Add review
Rx N
Generic name:
ponesimod systemic
Brand name:
Ponvory
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Tascenso ODT Rate Add review
Rx C N
Generic name:
fingolimod systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tyruko Rate Add review
Rx C N
Generic name:
natalizumab systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
alemtuzumab 6.5 21 reviews for alemtuzumab to treat Multiple Sclerosis
Rx C N
Generic name:
alemtuzumab systemic
Brand name:
Lemtrada
Drug class:
CD52 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Azasan Rate Add review
Rx D N
Generic name:
azathioprine systemic
Drug class:
antirheumatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Bafiertam Rate Add review
Rx N
Generic name:
monomethyl fumarate systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
corticotropin 5.5 11 reviews for corticotropin to treat Multiple Sclerosis
Rx C N
Generic name:
corticotropin systemic
Brand names:
Acthar, H.P. Acthar Gel
Drug class:
corticotropin
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Millipred Rate Add review
Rx C N
Generic name:
prednisolone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Millipred DP Rate Add review
Rx C N
Generic name:
prednisolone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
Orapred ODT Rate Add review
Rx C N
Generic name:
prednisolone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
PediaPred Rate Add review
Rx C N
Generic name:
prednisolone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
peginterferon beta-1a 5.3 15 reviews for peginterferon beta-1a to treat Multiple Sclerosis
Rx C N X
Generic name:
peginterferon beta-1a systemic
Brand name:
Plegridy
Drug class:
interferons
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Ponvory Rate Add review
Rx N
Generic name:
ponesimod systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
cyclophosphamide Off-label 6.0 3 reviews for cyclophosphamide to treat Multiple Sclerosis
Rx D N
Generic name:
cyclophosphamide systemic
Drug class:
alkylating agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
De-Sone LA Rate Add review
Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
Dxevo Rate Add review
Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
H.P. Acthar Gel 3.0 3 reviews for H.P. Acthar Gel to treat Multiple Sclerosis
Rx C N
Generic name:
corticotropin systemic
Drug class:
corticotropin
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
HiDex Rate Add review
Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
interferon beta-1b 7.0 7 reviews for interferon beta-1b to treat Multiple Sclerosis
Rx C N X
Generic name:
interferon beta-1b systemic
Brand names:
Betaseron, Extavia
Drug class:
interferons
For consumers:
dosage, interactions, side effects
Medrol 1.0 1 review for Medrol to treat Multiple Sclerosis
Rx C N
Generic name:
methylprednisolone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
mycophenolate mofetil Off-label 9.5 2 reviews for mycophenolate mofetil to treat Multiple Sclerosis
Rx D N
Generic name:
mycophenolate mofetil systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
siponimod 7.3 9 reviews for siponimod to treat Multiple Sclerosis
Rx N
Generic name:
siponimod systemic
Brand name:
Mayzent
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Acthar 4.8 6 reviews for Acthar to treat Multiple Sclerosis
Rx C N
Generic name:
corticotropin systemic
Drug class:
corticotropin
For consumers:
dosage, interactions, side effects
azathioprine 4.5 2 reviews for azathioprine to treat Multiple Sclerosis
Rx D N
Generic name:
azathioprine systemic
Brand names:
Imuran, Azasan
Drug class:
antirheumatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Dexamethasone Intensol Rate Add review
Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
Glatopa 4.3 9 reviews for Glatopa to treat Multiple Sclerosis
Rx B N
Generic name:
glatiramer systemic
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Imuran Rate Add review
Rx D N
Generic name:
azathioprine systemic
Drug class:
antirheumatics, other immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
mitoxantrone 10 2 reviews for mitoxantrone to treat Multiple Sclerosis
Rx D N
Generic name:
mitoxantrone systemic
Drug class:
antibiotics/antineoplastics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
prednisolone Rate Add review
Rx C N
Generic name:
prednisolone systemic
Brand names:
Millipred, Millipred DP, Orapred ODT, PediaPred
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Rebif Rebidose 8.3 4 reviews for Rebif Rebidose to treat Multiple Sclerosis
Rx C N X
Generic name:
interferon beta-1a systemic
Drug class:
interferons
For consumers:
dosage, interactions, side effects
Lemtrada 6.3 20 reviews for Lemtrada to treat Multiple Sclerosis
Rx C N
Generic name:
alemtuzumab systemic
Drug class:
CD52 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
methylprednisolone 6.0 3 reviews for methylprednisolone to treat Multiple Sclerosis
Rx C N
Generic name:
methylprednisolone systemic
Brand names:
Solu-Medrol, Medrol
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Solu-Medrol 9.0 1 review for Solu-Medrol to treat Multiple Sclerosis
Rx C N
Generic name:
methylprednisolone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
natalizumab 7.9 100 reviews for natalizumab to treat Multiple Sclerosis
Rx C N
Generic name:
natalizumab systemic
Brand names:
Tysabri, Tyruko
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Plegridy 5.4 14 reviews for Plegridy to treat Multiple Sclerosis
Rx C N X
Generic name:
peginterferon beta-1a systemic
Drug class:
interferons
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
teriflunomide 5.5 88 reviews for teriflunomide to treat Multiple Sclerosis
Rx X N X
Generic name:
teriflunomide systemic
Brand name:
Aubagio
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
valacyclovir Off-label 9.5 2 reviews for valacyclovir to treat Multiple Sclerosis
Rx B N
Generic name:
valacyclovir systemic
Drug class:
purine nucleosides
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Off-label:
Yes
dexamethasone 10 1 review for dexamethasone to treat Multiple Sclerosis
Rx C N
Generic name:
dexamethasone systemic
Brand names:
Dexamethasone Intensol, De-Sone LA, Dxevo, HiDex
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
fingolimod 7.1 97 reviews for fingolimod to treat Multiple Sclerosis
Rx C N
Generic name:
fingolimod systemic
Brand names:
Gilenya, Tascenso ODT
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Mayzent 7.3 8 reviews for Mayzent to treat Multiple Sclerosis
Rx N
Generic name:
siponimod systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Avonex Pen 8.8 13 reviews for Avonex Pen to treat Multiple Sclerosis
Rx C N X
Generic name:
interferon beta-1a systemic
Drug class:
interferons
For consumers:
dosage, interactions, side effects
Avonex Prefilled Syringe 9.0 5 reviews for Avonex Prefilled Syringe to treat Multiple Sclerosis
Rx C N X
Generic name:
interferon beta-1a systemic
Drug class:
interferons
For consumers:
dosage, interactions, side effects
dalfampridine 7.8 83 reviews for dalfampridine to treat Multiple Sclerosis
Rx C N
Generic name:
dalfampridine systemic
Brand name:
Ampyra
Drug class:
miscellaneous central nervous system agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
prednisone 1.0 1 review for prednisone to treat Multiple Sclerosis
Rx C N
Generic name:
prednisone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Briumvi 9.0 6 reviews for Briumvi to treat Multiple Sclerosis
Rx N
Generic name:
ublituximab systemic
Drug class:
CD20 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ublituximab 9.0 6 reviews for ublituximab to treat Multiple Sclerosis
Rx N
Generic name:
ublituximab systemic
Brand name:
Briumvi
Drug class:
CD20 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
diroximel fumarate 9.5 7 reviews for diroximel fumarate to treat Multiple Sclerosis
Rx N X
Generic name:
diroximel fumarate systemic
Brand name:
Vumerity
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
ofatumumab 6.7 61 reviews for ofatumumab to treat Multiple Sclerosis
Rx C N
Generic name:
ofatumumab systemic
Brand name:
Kesimpta
Drug class:
CD20 monoclonal antibodies, selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
ozanimod 8.7 4 reviews for ozanimod to treat Multiple Sclerosis
Rx N
Generic name:
ozanimod systemic
Brand name:
Zeposia
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
cladribine 8.2 6 reviews for cladribine to treat Multiple Sclerosis
Rx D N
Generic name:
cladribine systemic
Brand name:
Mavenclad
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Extavia Rate Add review
Rx C N X
Generic name:
interferon beta-1b systemic
Drug class:
interferons
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
interferon beta-1a 7.4 95 reviews for interferon beta-1a to treat Multiple Sclerosis
Rx C N X
Generic name:
interferon beta-1a systemic
Brand names:
Rebif, Avonex, Avonex Pen, Avonex Prefilled Syringe, Rebif Rebidose
Drug class:
interferons
For consumers:
dosage, interactions, side effects
Mavenclad 9.7 4 reviews for Mavenclad to treat Multiple Sclerosis
Rx D N
Generic name:
cladribine systemic
Drug class:
antimetabolites
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ocrelizumab 4.9 176 reviews for ocrelizumab to treat Multiple Sclerosis
Rx N
Generic name:
ocrelizumab systemic
Brand name:
Ocrevus
Drug class:
CD20 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Zeposia 8.7 4 reviews for Zeposia to treat Multiple Sclerosis
Rx N
Generic name:
ozanimod systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
dimethyl fumarate 6.5 109 reviews for dimethyl fumarate to treat Multiple Sclerosis
Rx C N
Generic name:
dimethyl fumarate systemic
Brand name:
Tecfidera
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Aubagio 5.4 86 reviews for Aubagio to treat Multiple Sclerosis
Rx X N X
Generic name:
teriflunomide systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Vumerity 9.4 6 reviews for Vumerity to treat Multiple Sclerosis
Rx N X
Generic name:
diroximel fumarate systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
glatiramer 7.3 150 reviews for glatiramer to treat Multiple Sclerosis
Rx B N
Generic name:
glatiramer systemic
Brand names:
Copaxone, Glatopa
Drug class:
other immunostimulants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Kesimpta 6.7 61 reviews for Kesimpta to treat Multiple Sclerosis
Rx C N
Generic name:
ofatumumab systemic
Drug class:
CD20 monoclonal antibodies, selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Betaseron 7.0 7 reviews for Betaseron to treat Multiple Sclerosis
Rx C N X
Generic name:
interferon beta-1b systemic
Drug class:
interferons
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Avonex 7.2 44 reviews for Avonex to treat Multiple Sclerosis
Rx C N X
Generic name:
interferon beta-1a systemic
Drug class:
interferons
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ampyra 8.0 77 reviews for Ampyra to treat Multiple Sclerosis
Rx C N
Generic name:
dalfampridine systemic
Drug class:
miscellaneous central nervous system agents
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tysabri 7.9 96 reviews for Tysabri to treat Multiple Sclerosis
Rx C N
Generic name:
natalizumab systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Gilenya 7.1 95 reviews for Gilenya to treat Multiple Sclerosis
Rx C N
Generic name:
fingolimod systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Rebif 6.9 29 reviews for Rebif to treat Multiple Sclerosis
Rx C N X
Generic name:
interferon beta-1a systemic
Drug class:
interferons
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Ocrevus 4.8 160 reviews for Ocrevus to treat Multiple Sclerosis
Rx N
Generic name:
ocrelizumab systemic
Drug class:
CD20 monoclonal antibodies
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tecfidera 6.3 98 reviews for Tecfidera to treat Multiple Sclerosis
Rx C N
Generic name:
dimethyl fumarate systemic
Drug class:
selective immunosuppressants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Copaxone 7.6 133 reviews for Copaxone to treat Multiple Sclerosis
Rx B N
Generic name:
glatiramer systemic
Drug class:
other immunostimulants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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