The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
RRMS for 3 years. Started Amphrya 1 week ago and saw results on first day! Truly amazing that I can feel all the way to my toes in my weaker left leg! I am so encouraged by this pill. I have had absolutely no side effects. Still only taking 1 pill per day since its been only 1 week. Please give this a try, I wish I would have and not waited 3 years.
I have had some minor side effects but nothing serious. I used to use a foot brace and cane, but once the medicine kicked in I put them both away and haven't needed them since. This medicine is a God send, and I hope it will work for you too.
Review by PositivelyMS (taken for less than 1 month):
User Rating:
9.0
I have been on Ampyra for 4 days and I can't remember the last time I felt this good. Left leg is working better, can stand for longer periods of time, and I think that is just the beginning. Like others, I am going to start retraining my body to get back to normal as much as I can. Going back to Mayo tomorrow to have strength retested for before and after. I am part of a study going on. Drug company is contributing to keep my copay to a minimum.
I started Ampyra five weeks ago. The first full day I was miserable with nausea but over the next few days the nausea lessened. Three weeks into taking it I realized that I wasn't tripping anymore and my right leg footdrop was all but gone. Now I'm trying to strengthen my leg muscles and walking on the treadmill and riding the exercise bike everyday. I've had RRMS for 17 years. Four years ago I was easily walking three miles a day without any problems, but over those last few years I was weakening, tripping, falling. I couldn't even walk a half mile. I was in a leg brace and using a cane frequently. Just seeing a set of stairs I was going to have to climb put me "over the edge". Now I'm going up the stairs and starting to walk much better.
10 users found this comment helpful.
Did you?YesNo
I have been taking this medicine for a year now, and it works great for me. I have relapsing-remitting MS, and I experience balance and coordination issues while walking (among other things). The FIRST time I took this (10mg extended release tablet) I noticed an immediate improvement in my ability to walk. All of a sudden, I was dashing up the stairs, which normally gave me trouble. I'm able to walk most of the time without my cane now! I have also noticed better bladder control. I know it is not a cure, but it greatly helps my MS symptoms. Ampyra has been a great blessing.
17 users found this comment helpful.
Did you?YesNo
I still use a scooter. But, I've had MS almost 40 years. Able to do physical therapy, stand. Much greater energy, significant lessening of my horrible fatigue, improved bowel. Effect leaves soon after the end of the dosage period. My husband loves how it's improved the quality of both our lives.
17 users found this comment helpful.
Did you?YesNo
Caused constipation, but the medicine has definitely increased the quality of life. I have been on it for 6 months and it is as good today as that first couple weeks.
20 users found this comment helpful.
Did you?YesNo
I have had amazing results with Ampyra. I was relying on a walker more and more often because of leg weakness. Within two days of starting the medication; I was back to a cane and not even full time. After two weeks; I can now stand on my own for 4-5 minutes and can walk much faster without foot drop. The only reason I didn't give it a 10 out of 10 is because of mild side effects (nausea and headache).
30 users found this comment helpful.
Did you?YesNo
It is an amazing medicine. My right foot drop has improved tremendously. I can wash dishes without having to sit halfway through. I am glad to read others are experiencing wonderful effects too. It is my miracle.
30 users found this comment helpful.
Did you?YesNo
It's been 9 yrs, and I am SP. Ampyra strengthens both legs. At times I walk on my own. When I did not have Ampyra, I needed my scooter. Now that I have Ampyra, I am walking again with my crutch cane. It's a start, I have no side effects, and I recommend trying Ampyra.
29 users found this comment helpful.
Did you?YesNo
Ampyra has made my quality of life a more positive experience! I used to have problems with my gait, Ampyra makes it so I am able to walk straight again. Also, I have noticed a drastic change in my cognitive functions. My thought process, language barrier and my ability to remember things short term has improved. I can really tell a difference if I forget a dose! Not a cure, but a step in the right direction!
39 users found this comment helpful.
Did you?YesNo
I have been taking Ampyra for 3 months and have noticed my weak leg is stronger and faster. My son noticed I was taking the stairs faster as well. I can put my leg in my pants while standing without using my hand to help it. I had insomnia at first but changed the times to 5 am and 5 pm with two ibuprofen at 5 am since I noticed some back pain in the mornings. That's gone.
31 users found this comment helpful.
Did you?YesNo
I have SP Multiple Sclerosis and when I first tried Ampyra I thought it was a miracle medicine. I have now been on it for over 1 year and the positive effects have unfortunately diminished. I have had shoulder pains for some time and I am going off Ampyra for 1 week to see about any changes.
29 users found this comment helpful.
Did you?YesNo
I love Ampyra. It's such a shame it is expensive to get. I can now make it to the bathroom in time. HUGE improvement with that alone. But I can walk upstairs without lifting my legs with my hands.
31 users found this comment helpful.
Did you?YesNo
I've taken Ampyra for seven months. I went from wheel chair to walker to cane in two months. Now I only use the cane when going out. It has done wonderful things for me.
40 users found this comment helpful.
Did you?YesNo
After 3 weeks on Ampyra I have recovered feeling and function in my left hand, after ten years. I have resumed seating, after decades. And a permanent brain fog has listed. My walking and balance are better, though I still use a walker. I consider it a miracle and feel mentally reborn.
49 users found this comment helpful.
Did you?YesNo
My husband has secondary progressive MS and has been using Ampyra for 1 month. He didn't see any changes at first, but we now notice that he has an easier time swallowing (he used to cough a lot while eating/drinking), he hasn't fallen at all and he thinks his balance is better. Since the changes have been subtle he is now keeping a diary of how he feels each day.
43 users found this comment helpful.
Did you?YesNo
I have taken AMPYRA for 1 month. The second day I thought it was my imagination but I did things I couldn't do before, like stand at the sink without leaning, lifting my legs much higher. My left arm was weak and almost always had a closed fist, not anymore. I can actually use the key board again with both hands. So much more to say, it is a miracle medicine. To bad, my insurance denied another month. Just purchased 15 day supply on my own ($592.50) while I fight the denial. Everyone should give it a try.
58 users found this comment helpful.
Did you?YesNo
I took my first dose today. The first thing I noticed was tingling in my legs and hands. As the day progressed my legs have felt less heavy, my left leg has dragged much less, I'm not shaking as bad and I have a lot more energy. I can't wait to see how I feel by the weekend.
46 users found this comment helpful.
Did you?YesNo
I have been on Ampyra for 5 days and have been so happy with this new pill. The first 2 days were NOT good with the side effects, but each day just gets better. I am able to walk better (without dragging my left foot) and get up from a kneeling position without to much effort. This new medicine has given me a new outlook on my future. Thank you for this medical wonder!
62 users found this comment helpful.
Did you?YesNo
I have used almost every medication known to man for primary progressive MS. Understanding that this is not a cure but, the improvement in my mobility is amazing.
I still lack a large range of motion. But, going to the gym now (which I could not do before) hoping to rebuild and retrain muscle that I have not used in years.
I'm not 100% but, I am way better than I was before and I'll take back what I can get back.
A little before the time to take my second dose I tend to start return to the state I was at before I started taking it. Second dose and I'm back up ready to face the world feet first.
This has given me so much hope after I have been disappointed numerous times before.
95 users found this comment helpful.
Did you?YesNo
Not a cure and I may have been expecting (hoping for) more, but it's working for me. I still use a cane to walk to the office (.33 mile), but I now get around the office without the cane, including going to the restroom, going for lunch, etc.
105 users found this comment helpful.
Did you?YesNo
XenoPort, Inc. (Nasdaq: XNPT) announced today top-line results from its pivotal Phase 3 clinical trial of arbaclofen placarbil (AP) for the treatment of...
-- 65 new grants and fellowships part of 2013 investment of over $47 million in cutting-edge research projects moving us closer to a world free of MS
NEW...