Tecfidera

Generic Name: dimethyl fumarate (dye METH il FUE mar ate)
Brand Names: Tecfidera

What is Tecfidera ?

Tecfidera (dimethyl fumarate) is a prescription medicine used to treat relapsing multiple sclerosis.

Tecfidera may also be used for purposes not listed in this medication guide.

Important information

Before taking and while you take Tecfidera, tell your doctor if you have or have had a low white blood cell counts or an infection.

Slideshow: Multiple Sclerosis: What's New in Treatment Options?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use Tecfidera if you are allergic to dimethyl fumarate.

To make sure Tecfidera is safe for you, tell your doctor if you have an active infection.

Your doctor may perform blood tests to make sure you do not have conditions that would prevent you from safely using this medicine.

FDA pregnancy category C. It is not known whether Tecfidera will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

See also: Pregnancy and breastfeeding warnings (in more detail)

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Tecfidera on the baby.

It is not known whether dimethyl fumarate passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take Tecfidera ?

Take Tecfidera exactly as your doctor has prescribed Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take Tecfidera with or without food.

Do not crush, chew, break, or open a capsule. Swallow it whole.

Tecfidera is usually given in two different strengths, one for a starter dose and the other for a maintenance dose. The starter dose is usually taken for only 7 days. Follow your doctor's dosing instructions very carefully.

Store at room temperature away from moisture, heat, and light. Throw away any unused capsules 90 days after you first opened the bottle.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Tecfidera Dosing Information

Usual Adult Dose for Multiple Sclerosis:

Initial dose: 120 mg orally twice a day for 7 days.
Maintenance dose: 240 mg orally twice a day.

Approved indication: The treatment of patients with relapsing forms of multiple sclerosis.

What other drugs will affect Tecfidera ?

Other drugs may interact with Tecfidera , including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

What should I avoid?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Tecfidera side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Tecfidera: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • fever, pain when swallowing, cold or flu symptoms;

  • severe stomach pain; or

  • severe feeling of warmth or tingling, or a burning sensation.

Common Tecfidera side effects may include:

  • nausea, diarrhea, stomach pain; or

  • flushing (warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Tecfidera ?

Other drugs may interact with Tecfidera , including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about Tecfidera .
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Tecfidera only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2014 Cerner Multum, Inc. Version: 1.01. Revision Date: 2013-07-10, 8:03:46 AM.

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