Prednisolone Dosage

Usual Adult Dose for Multiple Sclerosis

Tablets and syrup for acute exacerbations: 200 mg daily for one week followed by 80 mg every other day for 1 month.

Usual Adult Dose for Bronchopulmonary Dysplasia

Tablets and syrup for acute exacerbations: 200 mg daily for one week followed by 80 mg every other day for 1 month.

Usual Adult Dose for Anti-inflammatory

Sodium phosphate:

Oral: 5 to 60 mg per day in divided doses 1 to 4 times/day.

Intravenous or Intramuscular: 4 to 60 mg/day

For intraarticular, intralesional or soft tissue administration:
Large joints: 10 to 20 mg
Small joints: 4 to 5 mg
Bursae: 10 to 15 mg
Tendon sheaths: 2 to 5 mg
Soft tissue infiltration: 10 to 30 mg
Ganglia: 5 to 10 mg

Injectable suspension (tebutate) for intraarticular, intralesional or soft tissue administration:
Large joints: 20 to 30 mg (doses > 40 mg not recommended)
Small joints: 8 to 10 mg
Bursae: 20 to 30 mg
Tendon sheaths: 4 to 10 mg
Ganglia: 10 to 20 mg

Injectable suspension (acetate) for intraarticular, intralesional or soft tissue administration: 4 to 100 mg
Bursae: 10 to 15 mg
Tendon sheaths: 2 to 5 mg
Soft tissue infiltration: 10 to 30 mg

Usual Pediatric Dose for Immunosuppression

Oral: 0.1 to 2 mg/kg/day in divided doses 1 to 4 times a day.

Intravenous: 0.1 to 2 mg/kg/day in divided doses 1 to 4 times a day.

Usual Pediatric Dose for Asthma - Acute

Oral: 1 to 2 mg/kg/day in divided doses 1 to 2 times a day for 3 to 5 days.

Intravenous: 2 to 4 mg/kg/day divided 3 or 4 times a day.

Usual Pediatric Dose for Nephrotic Syndrome

First 3 episodes: Initial dose: 2 mg/kg/day (maximum dose 80 mg/day) until urine is free of protein for 3 consecutive days (maximum: 28 days); followed by 1 to 1.5 mg/kg/dose every other day for 4 weeks.

Frequent relapses or long-term maintenance dose: 0.5 to 1 mg/kg/dose given every other day for 3 to 6 months.

Usual Pediatric Dose for Bronchopulmonary Dysplasia

2 mg/kg/day orally divided twice daily for 5 days, followed by 1 mg/kg/day once daily for 3 days, followed by 1 mg/kg/dose every other day for 3 doses.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

Dosage adjustment should be based on severity of condition treated and response of patient.

Precautions

Avoid abrupt withdrawal after long-term therapy.

Dialysis

Supplemental dose is not necessary.

See also...