Ocrevus Side Effects
Generic name: ocrelizumab
Note: This document contains side effect information about ocrelizumab. Some dosage forms listed on this page may not apply to the brand name Ocrevus.
Applies to ocrelizumab: intravenous solution.
Serious side effects of Ocrevus
Along with its needed effects, ocrelizumab (the active ingredient contained in Ocrevus) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking ocrelizumab:
More common
- Back pain
- bloating or swelling of the face, arms, hands, lower legs, or feet
- blurred vision
- body aches or pain
- chest tightness
- chills
- confusion
- cough
- difficulty with breathing
- dizziness
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- ear congestion
- fast, pounding, or irregular heartbeat or pulse
- feeling of warmth
- fever
- headache
- hives, itching, or skin rash
- loss of voice
- nausea
- pain, redness, swelling, tenderness, or warmth on the skin
- rapid weight gain
- redness of the face, neck, arms, and occasionally, upper chest
- runny or stuffy nose
- sneezing
- sore throat
- sweating
- tingling of the hands or feet
- unusual tiredness or weakness
- unusual weight gain or loss
- vomiting
Less common
- Burning or stinging of the skin
- painful blisters on the trunk of the body
- painful cold sores or blisters on the lips, nose, eyes, or genitals
Incidence not known
- Eye pain or redness
- mental changes
- stiff neck
Other side effects of Ocrevus
Some side effects of ocrelizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Diarrhea
- discouragement
- feeling sad or empty
- irritability
- lack of appetite
- loss of interest or pleasure
- trouble concentrating
- trouble sleeping
For Healthcare Professionals
Applies to ocrelizumab: intravenous solution.
Respiratory
Very common (10% or more): Upper respiratory tract infection (49%), nasopharyngitis (24%), lower respiratory tract infection (10%)
Common (1% to 10%): Bronchitis, cough[Ref]
Psychiatric
Common (1% to 10%): Depression[Ref]
Oncologic
Uncommon (0.1% to 1%): Breast cancer[Ref]
Musculoskeletal
Common (1% to 10%): Back pain, pain in extremity[Ref]
Local
Very common (10% or more): Infusion reactions (40%)[Ref]
Immunologic
Common (1% to 10%): Herpes virus associated infections
Frequency not reported: Immunogenicity[Ref]
Hematologic
Very common (10% or more): Neutrophil levels decreased (13%)[Ref]
Dermatologic
Very common (10% or more): Skin infections (14%)[Ref]
Ocular
Common (1% to 10%): Conjunctivitis[Ref]
Metabolic
Common (1% to 10%): Peripheral edema[Ref]
Frequently asked questions
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More about Ocrevus (ocrelizumab)
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References
1. Product Information. Ocrevus (ocrelizumab). Genentech. 2017.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.