This dosage information may not include all the information needed to use Fingolimod safely and effectively. See additional information for Fingolimod.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Multiple Sclerosis
Initial dose: 0.5 mg orally once daily.
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
Mild to moderate liver dysfunction: No adjustment recommended.
Severe liver dysfunction: Caution and close monitoring are recommended.
Although no specific dose adjustment guidelines have been suggested, caution is recommended in elderly patients (65 years of age or older).
Following the first dose, all patients, including those where therapy has been interrupted for more than 2 weeks, should be monitored for 6 hours for signs and symptoms of bradycardia.
Blood pressure should be monitored throughout treatment.
Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).
Data not available
The US FDA requires a Risk Evaluation and Mitigation Strategy (REMS) for fingolimod. It includes a Medication Guide and communication plan. Additional information is available at www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm111350.htm.
Fingolimod may be administered with or without food.
Doses greater than 0.5 mg daily have been associated with a higher incidence of adverse effects and no additional benefit.