Kesimpta User Reviews & Ratings

• Miss...
• December 28, 2022

For Multiple Sclerosis "My brother took one injection each in December, Jan. and Feb. He died September 10, 2022 after four 1/2 months in three hospitals and 11 weeks in rehab/nursing homes. After the third injection he felt worse than before. ICU doctors said he had a reaction to Kesimpta. He had a heart attack at home; in the hospital, he had recurrent UTI's, pneumonia 6 times, caught COVID after being vaccinated, stroke, mini-stroke, hematoma from his knee to thigh, clotting problems, drop foot, MRSA pneumonia, collapsed lung, aspiration pneumonia, and other problems, He couldn't walk after going to the hospital. He stopped carrying on conversations in the hospital. He was tortured by a medication that he thought would help. PLEASE DO NOT take Kesimpta."

• Kemul...
• Taken for 1 to 6 months
• November 23, 2023

For Multiple Sclerosis "I was apprehensive about starting my course of treatment, but I'm glad I did. I realize this treatment doesn't 'fix' pre-existing issues, but from my own experiences so far (dose 4 now), my mobility and cognitive abilities are much improved. It's not night and day, but it's cleared the fog, and I feel much more like my old self. I've also found my susceptibility to pseudo-relapses has improved also, without any real 'off' days since starting the medication. The first dose was quite unpleasant, with a high temperature, fast pulse, chills that kicked in about 4/5 hrs after it was administered. I took some ibuprofen and slept through it, woke up in the morning feeling OK, no issues at all since. The auto-injector pen is brilliant, very easy to use and hard to mess up, and more importantly, not painful! I'm glad I went down this route rather than infusion-based treatments as each dose only takes a few minutes. The convenience combined with its efficacy is its biggest bonus."

• Mommi...
• Taken for 6 months to 1 year
• November 10, 2022

For Multiple Sclerosis "I was on Tysabri for 13 years and became JCV+ therefore meds had to change. I started Kesimpta 1 a month shot you do yourself, but I have felt awful since the first injection. I am now 9 months in. I have been having muscle spasms galore, migraines for 9 days straight after taking shot, my legs are so heavy, drop foot has gotten a lot worse, overall I feel like crap. I am in touch with the Dr and all I keep being told is wait for the MRI in November to see if it is working. I don't think it's working I feel like I am progressing rapidly. I did great on Tysabri I want to go back to that but don't think dr will allow that. At this point I'm ready to go all off everything, but I know I will progress even faster. I am lost."

• Patie...
• Taken for 1 to 2 years
• March 24, 2023

For Multiple Sclerosis "I have been on Kesimpta for almost 2 years. It’s my first medication for RRMS. At first, it was okay then I started getting sick all the time. I can’t keep up with the colds and sickness, no immune system. It also seems to affect my smell. Which I’m guessing comes with tongue issues - horrid sores, a thick coating of fur, and very sensitive. The worst part is being sick all the time and the migraines, not being able to taste or eat due to sores and mouth ulcers. Oh, I also need to see a cardiologist and be on blood pressure medication at 31 years old, and wear a halter monitor for two weeks because my heartbeat is so fast and irregular. 116 resting. I stopped taking it for three months while I had a tooth infection - and felt better. my Neuro urged me to keep taking it until the next MRI. I don’t want to be unprotected from progression, but I also need quality of life. I despise having to take this drug."

• Kano
• Taken for 1 to 2 years
• March 18, 2021

For Multiple Sclerosis "I was included in the clinical trials for this med, I was on it for a little over 2 years. My experience wasn't great, although I didn't develop any new lesions. Despite that my MS still progressed to me needing a cane to assist with walking most of the time. My immune system was completely gone but I didn't develop common illnesses, instead I developed shingles 4 times in less than two years, cellulitis on my face/ear, meningitis and I was hospitalized twice (once for three days and the second for almost two weeks). I was unable to stand up quickly for most of the two years due to dizziness/fainting upon doing so. I suffered with throat issues and loss of voice several times as well."

• PJano
• Taken for less than 1 month
• September 29, 2022

For Multiple Sclerosis "I took my first dose last Friday and really don't want to take the 2nd dose tomorrow. I took Kesimpta around 2pm and by 6pm I was having chills and shaking that got worse, what really bothered me was the fever, I didn't have a thermometer, but it was so bad that my vision was very blurry, had a severe headache, was throwing up, my right leg went numb, I peed myself, my heartbeat was pounding and super-fast, couldn't get off the floor for hours. I'm 55 and live by myself so I was scared. Don't like this medicine!"

• Hilts
• Taken for 1 to 6 months
• October 3, 2023

For Multiple Sclerosis "Well, done the 3 loading doses and what brilliant stuff this is! Got the flu type reaction after the 1st, but was expecting that so not a problem - nothing after the next 2 apart from a bit of tiredness. Symptoms - hugely reduced. Buzzing in leg and arm improving massively. Interesting other things as well - I have always been an allergic/inflammatory kinda chick, insect bites, plants, antibiotics, acne etc., etc. well chopped a load of foliage down over weekend AND nothing. Not even an itch. Got bitten as well, and again nothing. Makes you wonder about MS/allergies/inflammation. My body telling me they must be linked???"

• Ikesmom
• Taken for less than 1 month
• February 14, 2024

For Multiple Sclerosis "I have RRMS, this is my 5th med to try. I took the first injection, which of ANY self-injection was the easiest I have ever done (no pain, didn’t even feel it, so kudos there!) waited for the side effects and thought I was home free. I always did great on Ocrevus, like a burst of energy great, so I thought maybe it would be like that. Two days went by and nothing. Then the third day, almost 72 hours exactly, it hit. I got widespread muscle spasms from my back to my toes. I got deep bone and joint pain, even my ear canals and fingernails hurt. I ran fevers up to 104 all night. By morning, I just felt tired and VERY sore for the rest of the day, for 3 days I was very sore and slow moving. Not sure if I can do this since I am a mom, too. But desperate to slow down my progression. Not sure what to do."

• Hilts
• Taken for 1 to 6 months
• October 3, 2023

For Multiple Sclerosis "Well. Done my loading 3 and really pleased. Got the flu-like reaction after the first, but nothing paracetamol, ibuprofen, and piriton couldn't deal with. Next 2 - nothing apart from a tad tired and a tad itchy. Symptoms = never had one of those major relapse things, but MRI always very busy! Current symptom was buzzing in the left leg and arm, and it’s almost gone! Now less than intermittent rather than constant. A very weird (pleasurable) side effect is that it seems to have switched off my allergy to mosquito bites - normally spectacular reactions, but bitten weekend just gone and nada, not even itchy!! Seems to have turned down my overactive immune system."

• Marion...
• Taken for less than 1 month
• October 2, 2022

For Multiple Sclerosis "This medicine is the worse. I had side effects I ever had I had a sore throat, itching, legs tighting please guys don't take this med. Cause before I had this medicine I look at all the bad comments and I just didn't think it would happen to me wow! But it did"

• kIrel...
• Taken for 6 months to 1 year
• July 20, 2023

For Multiple Sclerosis "This is my third treatment for RRMS. Having been on Brabio and Plegridy and having awful adverse side effects, I needed to radically change my MS management and treatment to something new. I researched a lot into Kesimpta and in August '23, I started on it. Initially, there were many side effects. Initial loading doses induced flu-like symptoms, which would fizzle out after a few days. After about three months, I was just getting headaches after injecting. Now, these did develop into migraines, which sometimes would last for weeks on end. However, after 6 months on it, the side effects settled and I can confidently predict what will happen. I jab, within three days I can get a bit of a migraine, and that lasts a day or two. Due to my job, I get an MRI every six months, and both my previous scans were stable with no symptoms. I feel very positive about Kesimpta now, after a tough enough start. I have loads of energy, feel positive and GOOD which I did not on both previous. I feel normal at last!"

• lesli...
• Taken for 1 to 6 months
• September 3, 2023

For Multiple Sclerosis "I am a 40 yr. warrior, I still walk although Covid injections took a lot of my balance away. Kesimpta has worked wonderfully for me!!! I have done every MS drug out there, but this works for me, minor side effects that are gone after 4 months! I only wish more people were on it."

• Darren...
• Taken for 6 months to 1 year
• March 15, 2024

For Multiple Sclerosis "I was diagnosed with RRMS. I've been on Kesimpta for 10 months. It is very convenient and easy to administer. So far, I've had no issues with Kesimpta. My recent full MRI showed no further progression."

• Infor...
• Taken for 2 to 5 years
• December 9, 2022

For Multiple Sclerosis "Just some advice for the first injection: if and when fever spikes use ice packs under your arms and a cooling vest. I didn’t do this till my other half called the nurse in the family. The first injection is the only one I have had any issues with. And I have had well over 2 years' worth of injections. Still good days and bad days. Pretty stable and improved MRI activity. Best of luck to those beginning Kesimpta and continuing treatment."

• Tes
• Taken for 1 to 6 months
• September 5, 2022

For Multiple Sclerosis "I took the shot yesterday for the first time. Taking the shot was painless. I took the shot in my right thigh at 11:30am. I did house work afterwards. At 1pm I decided to take a nap. At 3:30 I woke up to use the bathroom. My legs were so stiff that I took too long and urinated on the floor. Then I took a hard fall to the floor. I spent 3 hours trying to get up. My legs felt heavy and stiff. I finally made it onto my bed. I could not roll over. It is the next day at 4am my legs feel better. I was able to walk downstairs. I am feeling better. I hope that I see improvement in my health."

• Denise
• Taken for 1 to 6 months
• September 21, 2022

For Multiple Sclerosis "The first three doses gave me flu-like symptoms and migraines. I felt like I was improving…at first. Less falls, and better balance. However, after taking August’s monthly injection around the 1st, I developed a kidney infection. Because I was in so much pain, extremely weak, with week-long diarrhea, the ER gave me IV antibiotics, and a bag of fluids. I’ve been through two rounds of oral antibiotics, yet it’s 9/20 and I can’t seem to shake this infection. I’m drinking plenty of fluids, like 4 full Yeti cups of water mixed with cranberry juice, but my urine output is low, I’m swollen all over, and I have flank pain with extreme fatigue. My neurologist visit is this Thursday…9/20. Honestly, I’m uneasy about what’s happening to me. None of these issues before Kesimpta. September’s injection is still in the fridge. Ask lots of questions if you’re offered this treatment…wish I had!"

• Nat
• Taken for less than 1 month
• December 28, 2023

For Multiple Sclerosis "I just had my second dose of Kesimpta yesterday. It's fantastic. I was previously on Ocrevus for a year and a half, and it floored me every time for at least a week. I had to take time off work as I wasn't able to function. Kesimpta is a game changer for me. No side effects for me, and it's super easy to self-administer. I am over the moon with it and cannot recommend it highly enough."

• Anonymous
• Taken for 1 to 6 months
• January 11, 2023

For Multiple Sclerosis "I completed Kesimpta’s three loading doses in November of 2022. For each injection, I took one Tylenol, one Benadryl, and a Pepcid later on - I think this definitely helped with the fever, body aches, and nausea. I was previously on Ocrevus but was unable to walk out of the facility after my last infusion (I had switched from the 6/7 hour infusion to the 4 hour one). I didn’t take any disease-modifying drugs for the next year, until Kesimpta in November 2022 at the suggestion of a neuro. My lymph nodes in my neck/jaw have been swollen since November 8 (date of first injection) and I have had different infections since (a double ear infection, recurring upper respiratory infections). I feel like I always have a mild fever and am kind of miserable now, haha. I’ve also lost my voice several times which is the first time that’s happened in my life! My lymph nodes are swollen to the point that it is also making it painful to speak. 0/10"

• PGM
• Taken for less than 1 month
• August 19, 2022

For Multiple Sclerosis "First injection a few days ago. Felt fine for the first few hours but then got headache/chills. I wasn't too bothered, it was all pretty mild. But about six hours in, things got worse. Flu-like symptoms, but severe: fever, aches, chills worsened. I tried to go to bed and just stayed there until I had to get up for the toilet. This would've been about 8 hours in. I couldn't stand on my own, and struggled (with my partner's help) to get to/from the toilet. Managed to get back to the bed, but had to pull my legs on as I just couldn't lift them. At that point, the chills/headache had gone but I was very hot. Finally, after about 10-11 hours, things started to get better and I was even able to sleep. Got up once more (around 12 hours) and was able to do everything unaided. Completely fine in the morning. Very uncertain about doing any more as, frankly, it was frightening."

• MrsWe...
• Taken for 1 to 6 months
• September 25, 2021

For Multiple Sclerosis "Migraines. Intense nightly migraines. I think this is more an issue if you suffer from any way but I hadn’t gotten them in over two years so when they returned so aggressively I was shocked. Then my neurologist expressed that another patient of her also has been getting them since she started on Kesimpta. I love the ease of use but not worth literal hours in bed from migraines."

• Melissa
• Taken for 6 months to 1 year
• January 14, 2023

For Multiple Sclerosis "I was diagnosed with MS in 2001 I was immediately put on Rebif I couldn’t tolerate it! So I struggled with episodes! When my father died then I started going downhill. Within 2 years I can’t walk without a walker! I can’t work anymore and I struggle every day to function! I tried Ocvervus & I couldn’t get through the first infusion cycle but then my doctor suggested Kesimpta & after the first dose I had immediate improvement! I’m in physical therapy & never felt stronger! I have 13 mm oval-shaped lesion that was found over two years ago & has been stable & no new lesions since taking the Kesimpta so if it worked for me they’re still hope for you! Don’t give up!"

• Jacob...
• Taken for less than 1 month
• December 2, 2022

For Multiple Sclerosis "The 1st dose was rough for loading dose. 1st one, I experienced chills and shakes that were uncontrollable. The absolute worst headache I have ever experienced and I felt like I needed to vomit but couldn't. Taken at 1900, awoke at 2300 and I wasn't able to fall asleep again until 0400. Did not want to take the next dose, but did. Minor headache, no chills taken at 1900, headache woke me at 0300 but I was able to get up and take acetaminophen and back to bed. 3rd dose, I had read about taking Benadryl 1 hour prior to dosing with acetaminophen. Taken meds at 1800, dosed at 1900. Woke about 0330 but was able to drink some water and went back to bed. By the 3rd dosing I believe I was acclimated to the drug, but I am worried about a repeat of 1st experience now that it is going to go to monthly. I do not see improvements in symptoms, e.g. fatigue, room spinning, tingling in arms and legs. I will update after about 6 months of injection."

• Kesim...
• Taken for 1 to 6 months
• April 19, 2023

For Multiple Sclerosis "Being realistic about MS meds and side effects, I know they cause pains, fatigue, and other unfavorable side effects. I got through the loading doses, the side effects were akin to having a short but very severe flu. I was prepared for that. I tend to feel like a normal person towards the next dose when enough time has passed. I like not having constant severe pain like I did on copaxone. However, I wish that medical professionals would stop minimizing and undertreating the pain of this disease and how it can be further aggravated by taking DMDs. There are times on Copaxone and Kesimpta that I dread the myalgia resulting from the scheduled dose because I know the aleve or advil the doctor nurse has emphatically declared will cure, won't fully help. The increased risk of sunburn was surprising and the constant scalp irritation even with intense conditioning and hydration has been baffling. That being said, I'm still grateful to be functional with a medicine that only requires once a month dosing."

• Yardley
• Taken for less than 1 month
• January 24, 2023

For Multiple Sclerosis "My sibling had their first dosage, and it was horrifying to see the side effects on them and they had had a terrible reaction including the common symptoms as well as others. As much as I would like to be optimistic, I still do not trust it and I am greatly shocked the UK has put this out on the market for use so quick. The only good thing is that it seems easy to administer, the device itself. However, it's the stuff being pumped into the patient that concerns me most. The dosage is too high in my opinion and it should be lower or adjusted to the patient and their tolerance level. I am scared for my sibling. I am monitoring this treatment like a hawk. I wish somewhere out there, there was a cure for MS or any condition without doing more damage to peoples health at all."

• My...
• October 23, 2022

For Multiple Sclerosis "I was diagnosed with RRMS in March 2021 and went with Kesimpta as my first treatment. The loading doses were rough: flu-like symptoms, incontinence, extreme fatigue. I did have a flare in between in the 2nd and 3rd loading doses. I almost fell while on the treadmill and had trouble walking around my house. Also had other new symptoms, which prompted an emergency brain MRI. Neuro said my body may have been adjusting to the med change, so I continued on the monthly injections to this day. Annual brain and spine MRIs this year showed no new lesions, atrophy, or black holes. The main symptom was extreme fatigue, usually the week before my next shot. It used to be a lot worse in that I would have to take that week off from working out, which is a big deal for me, as exercise is very important to me. Now I am able to workout 5-6 days per week and I love it. Of course I still have the usual daily fatigue and other symptoms that come with MS, but I am able to still work, exercise, drive, etc."