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Vicks Nature Fusion Cough Side Effects

Generic name: dextromethorphan

Medically reviewed by Last updated on Sep 11, 2023.

Note: This document contains side effect information about dextromethorphan. Some dosage forms listed on this page may not apply to the brand name Vicks Nature Fusion Cough.

Applies to dextromethorphan: oral capsule liquid filled, oral elixir, oral liquid, oral solution, oral suspension extended release, oral syrup, oral tablet.

Serious side effects

Along with its needed effects, dextromethorphan (the active ingredient contained in Vicks Nature Fusion Cough) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking dextromethorphan:

Symptoms of overdose

Other side effects

Some side effects of dextromethorphan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

For Healthcare Professionals

Applies to dextromethorphan: compounding powder, oral capsule, oral disintegrating strip, oral drops, oral liquid, oral lozenge, oral solution, oral suspension extended release, oral syrup, oral tablet chewable.


Adverse effects have included gastrointestinal disturbances such as stomach upset and diarrhea.[Ref]

Nervous system

Frequency not reported: Drowsiness, dizziness, convulsions[Ref]


Frequency not reported: Respiratory depression[Ref]


Frequency not reported: Vomiting, nausea, diarrhea, abdominal pain, gastrointestinal disturbance[Ref]


Rare (less than 0.1%): Fixed-drug eruptions[Ref]


Frequency not reported: Mental confusion, excitation, insomnia, abuse[Ref]

Cases of abuse have been reported.[Ref]


Frequency not reported: Rash, angioedema, pruritus, urticaria[Ref]

Frequently asked questions

More about Vicks Nature Fusion Cough (dextromethorphan)

Patient resources

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1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

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3. Helfer J, Kim OM (1990) "Psychoactive abuse potential of Robitussin-DM." Am J Psychiatry, 147, p. 672-3

4. Murray S, Brewerton T (1993) "Abuse of over-the-counter dextromethorphan by teenagers." South Med J, 86, p. 1151-3

5. Wolfe TR, Caravati EM (1995) "Massive dextromethorphan ingestion and abuse." Am J Emerg Med, 13, p. 174-6

6. Polles A, Griffith JL (1996) "Dextromethorphan-induced mania." Psychosomatics, 37, p. 71-4

7. Bostwick JM (1996) "Dextromethorphan-induced manic symptoms in a bipolar patient on lithium." Psychosomatics, 37, p. 571-2

8. Stubb S, Reitamo S (1990) "Fixed-drug eruption due to dextromethorphan ." Arch Dermatol, 126, p. 970-1

9. Knowles SR, Weber E (1998) "Dextromethorphan anaphylaxis." J Allerg Clin Immunol, 102, p. 316-7

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.