Trandolapril Side Effects
Medically reviewed by Drugs.com. Last updated on Aug 31, 2023.
Commonly reported side effects of trandolapril include: cough, dizziness, and hypotension. Other side effects include: cardiogenic shock, syncope, hyperkalemia, increased serum creatinine, and increased blood urea nitrogen. Continue reading for a comprehensive list of adverse effects.
Applies to trandolapril: oral tablet.
Oral route (Tablet)
Discontinue trandolapril as soon as possible if the patient becomes pregnant, as drugs that target the renin-angiotensin system can cause injury and death to the developing fetus.
Serious side effects of Trandolapril
Along with its needed effects, trandolapril may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking trandolapril:
- Blurred vision
- difficulty with breathing
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- irregular heartbeat
- numbness or tingling in the hands, feet, or lips
- stomach pain
- unusual tiredness or weakness
- weakness or heaviness of the legs
- Chest pain or discomfort
- cool, sweaty skin
- difficulty with speaking
- double vision
- inability to move the arms, legs, or facial muscles
- muscle cramps in the hands, arms, feet, legs, or face
- numbness and tingling around the mouth
- slow heartbeat
- stomach cramps
Other side effects of Trandolapril
Some side effects of trandolapril may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- stomach discomfort or upset
- Burning feeling in the chest or stomach
- difficulty with moving
- joint pain
- muscle aches, pain, or stiffness
- swollen joints
- tenderness in the stomach area
For Healthcare Professionals
Applies to trandolapril: oral tablet.
The most frequently reported side effects were dizziness and a dry, nonproductive cough.[Ref]
Very common (10% or more): Cough (up to 35%)
Common (1% to 10%): Bronchitis, upper respiratory tract infections, rhinitis
Uncommon (0.1% to 1%): Dyspnea, sore throat, hoarseness, epistaxis, throat inflammation
Very common (10% or more): Dizziness (up to 23%)
Common (1% to 10%): Headache
Rare (less than 0.1%): Muscle convulsions, disturbance of balance[Ref]
Very common (10% or more): Hypotension (up to 11%)
Common (1% to 10%): Orthostatic effects, syncope, bradycardia, cardiogenic shock, intermittent claudication, stroke, percutaneous transluminal coronary angioplasty, coronary artery bypass graft surgery
Uncommon (0.1% to 1%): Myocardial infarction, cerebrovascular accident, palpitations, tachycardia, Raynaud's phenomenon, chest pain, arrhythmias, angina pectoris, cerebral hemorrhage, AV first degree block, edema, flushing
Frequency not reported: Vasculitis
Postmarketing reports: Myocardial ischemia, cardiac failure, ventricular tachycardia[Ref]
Common (1% to 10%): Renal dysfunction, elevated BUN, increased creatinine
Uncommon (0.1% to 1%): Deterioration of renal function, acute renal failure
Rare (0.01% to 0.1%): Uremia
Very rare (less than 0.01%): Bacterial interstitial nephritis[Ref]
Common (1% to 10%): Rash
Rare (0.01% to 0.1%): Loss of appetite
Very common (10% or more): Increased serum uric acid (15%)
Rare (0.01% to 0.1%): Hyponatremia
Uncommon (0.1% to 1%): Decreased leukocytes, decreased neutrophils
Rare (0.01% to 0.1%): Decreased hemoglobin, decreased hematocrit
Frequency not reported: Elevated red blood cell sedimentation rate (ESR), leukocytosis
Common (1% to 10%): Myalgia
Uncommon (0.1% to 1%): Muscle cramps, pain in extremities
Common (1% to 10%): Urinary infection
Uncommon (0.1% to 1%): Impotence, decreased libido
Rare (0.01% to 0.1%): Proteinuria
Very rare (less than 0.01%): Oliguria, anuria[Ref]
Uncommon (0.1% to 1%): Increased liver enzymes
Rare (0.01% to 0.1%): Increased serum bilirubin
Postmarketing reports: Allergic hypersensitivity reactions (including pruritus and rash)[Ref]
Uncommon (0.1% to 1%): Abnormal feeling
Rare (less than 0.1%): Tinnitus
Uncommon (0.1% to 1%): Mood alterations, anxiety, depression
Rare (less than 0.1%): Mental confusion, nervousness
Postmarketing reports: Hallucinations[Ref]
Rare (less than 0.1%): Gynecomastia[Ref]
Rare (less than 0.1%): Blurred vision[Ref]
Frequency not reported: Positive antinuclear antibodies (ANA)[Ref]
More about trandolapril
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- Drug class: Angiotensin Converting Enzyme Inhibitors
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Related treatment guides
1. Product Information. Mavik (trandolapril). Knoll Pharmaceutical Company. 2001.
2. Cerner Multum, Inc. UK Summary of Product Characteristics.
3. Cerner Multum, Inc. Australian Product Information.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.