Nytol Side Effects
Generic Name: diphenhydramine
Note: This document contains side effect information about diphenhydramine. Some of the dosage forms listed on this page may not apply to the brand name Nytol.
More frequent side effects include: sedation and thickening of bronchial secretions. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to diphenhydramine: oral capsules and tablets, parenteral injection
Side effects include:
Sedation, sleepiness, dizziness, disturbed coordination, epigastric distress, thickening of bronchial secretions.
For Healthcare Professionals
Applies to diphenhydramine: compounding powder, injectable solution, oral capsule, oral disintegrating strip, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating
The most commonly reported side effects included somnolence, dizziness, and incoordination.[Ref]
Common (1% to 10%): Sedation/somnolence/sleepiness, drowsiness, unsteadiness, dizziness, headache, attention disturbance
Rare (0.01% to 0.1%): Extrapyramidal effects, tremor, convulsions
Frequency not reported: Paresthesia, dyskinesia/muscle dyskinesia, vertigo, neuritis, incoordination, psychomotor impairment, activation of epileptogenic foci[Ref]
Drowsiness usually diminishes after a few days.[Ref]
Common (1% to 10%): Dry mouth
Frequency not reported: Gastrointestinal disturbance, nausea, vomiting, constipation, diarrhea, dyspepsia, epigastric distress[Ref]
Common (1% to 10%): Fatigue
Frequency not reported: Lassitude, tinnitus, acute labyrinthitis, asthenia, chills, impaired performance (including impaired driving, work, and/or information processing)[Ref]
Rare (0.01% to 0.1%): Confusion, depression, sleep disturbances
Frequency not reported: Paradoxical excitation/excitation, agitation, increased energy, restlessness, nervousness, euphoria, anxiety, hallucinations, insomnia, irritability[Ref]
Rare (0.01% to 0.1%): Palpitations, hypotension, arrhythmia
Frequency not reported: Tachycardia, chest tightness, extrasystoles[Ref]
Rare (0.01% to 0.1%): Blood disorders
Frequency not reported: Hemolytic anemia, thrombocytopenia, agranulocytosis[Ref]
Rare (0.01% to 0.1%): Hypersensitivity reactions
Frequency not reported: Angioedema, anaphylactic shock[Ref]
Rare (0.01% to 0.1%): Liver dysfunction[Ref]
Frequency not reported: Rash, urticaria, skin rashes, erythema, photosensitivity, pruritus, drug rash, excessive perspiration[Ref]
Frequency not reported: Dyspnea, thickening of bronchial secretions, throat tightening, wheezing, nasal stuffiness, dry nose or throat[Ref]
Frequency not reported: Urinary hesitancy/difficulty/retention, dysuria, early menses[Ref]
Frequency not reported: Blurred vision, dry eyes, diplopia[Ref]
Frequency not reported: Increased appetite, anorexia[Ref]
Frequency not reported: Muscle twitching/weakness[Ref]
1. Cerner Multum, Inc. "Australian Product Information." O 0
2. "Product Information. Benadryl Childrens Allergy Fastmelt (diphenhydrAMINE)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
4. "Product Information. Benadryl (diphenhydramine)." Parke-Davis, Morris Plains, NJ.
Some side effects of Nytol may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
More about Nytol (diphenhydramine)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- 6 Reviews – Add your own review/rating
- Drug class: anticholinergic antiemetics
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