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Myambutol Side Effects

Generic name: ethambutol

Medically reviewed by Last updated on Nov 25, 2022.

Note: This document contains side effect information about ethambutol. Some dosage forms listed on this page may not apply to the brand name Myambutol.

Applies to ethambutol: oral tablet.

Serious side effects of Myambutol

Along with its needed effects, ethambutol (the active ingredient contained in Myambutol) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ethambutol:

Less common

  • Chills
  • pain and swelling of joints, especially big toe, ankle, or knee
  • tense, hot skin over affected joints


  • Blurred vision, eye pain, red-green color blindness, or any loss of vision (more common with high doses)
  • fever
  • joint pain
  • numbness, tingling, burning pain, or weakness in hands or feet
  • skin rash

Other side effects of Myambutol

Some side effects of ethambutol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

For Healthcare Professionals

Applies to ethambutol: oral tablet.


The most commonly reported side effects included decreased visual acuity and optic neuritis.[Ref]


Common (1% to 10%): Decreased visual acuity, optic neuritis

Uncommon (0.1% to 1%): Color blindness, eye pain, loss of vision, scotoma, visual disturbances

Frequency not reported: Irreversible blindness, optic neuropathy, retrobulbar neuritis[Ref]

Nervous system

Uncommon (0.1% to 1%): Visual field defect

Rare (0.01% to 0.1%): Extremity paresthesia (extremity numbness/tingling), numbness, peripheral neuritis, peripheral neuropathy

Very rare (less than 0.01%): Dizziness, headache[Ref]


Uncommon (0.1% to 1%): Hyperuricemia

Very rare (less than 0.01%): Gout

Frequency not reported: Anorexia, precipitation of acute gout[Ref]


Rare (0.01% to 0.1%): Pruritus, rash, Stevens-Johnson syndrome, toxic epidermal necrolysis, urticaria

Very rare (less than 0.01%): Bullous dermatitis, epidermal necrolysis, photosensitive lichenoid eruptions

Frequency not reported: Cutaneous reactions, dermatitis, erythema multiforme, exfoliative dermatitis[Ref]


Rare (0.01% to 0.1%): Thrombocytopenia/reversible thrombocytopenia

Very rare (less than 0.01%): Leukopenia, neutropenia

Frequency not reported: Eosinophilia, lymphadenopathy[Ref]


Very rare (less than 0.01%): Anaphylactic reaction, anaphylactoid reactions, hypersensitivity, hypersensitivity syndrome[Ref]


Very rare (less than 0.01%): Disorientation, hallucinations, mental confusion[Ref]


Very rare (less than 0.01%): Pneumonitis, pulmonary infiltrates with/without eosinophilia[Ref]


Very rare (less than 0.01%): Fever, malaise, pyrexia[Ref]


Very rare (less than 0.01%): Hepatic failure

Frequency not reported: Abnormal liver function test values, hepatitis, jaundice, liver toxicity/fatal liver toxicity, transient impairment of liver function[Ref]


Very rare (less than 0.01%): Interstitial nephritis[Ref]


Very rare (less than 0.01%): Joint pain[Ref]


Frequency not reported: Abdominal pain, diarrhea, gastrointestinal disorders, gastrointestinal upset, nausea, vomiting[Ref]


Frequency not reported: Myocarditis, pericarditis[Ref]


1. "Product Information. Myambutol (ethambutol)." Lederle Laboratories (2002):

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.