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Myambutol Dosage

Generic name: ETHAMBUTOL HYDROCHLORIDE 400mg
Dosage form: tablet, film coated

The information at Drugs.com is not a substitute for medical advice. Always consult your doctor or pharmacist.

MYAMBUTOL should not be used alone, in initial treatment or in retreatment. MYAMBUTOL should be administered on a once every 24-hour basis only. Absorption is not significantly altered by administration with food. Therapy, in general, should be continued until bacteriological conversion has become permanent and maximal clinical improvement has occurred.

MYAMBUTOL is not recommended for use in pediatric patients under thirteen years of age since safe conditions for use have not been established.

Initial Treatment:

Initial Treatment:

In patients who have not received previous antituberculous therapy, administer MYAMBUTOL 15 mg/kg (7 mg/ lb) of body weight, as a single oral dose once every 24 hours. In the more recent studies, isoniazid has been administered concurrently in a single, daily, oral dose.

Retreatment:

Retreatment: 

In patients who have received previous antituberculous therapy, administer MYAMBUTOL 25 mg/kg (11 mg/lb) of body weight, as a single oral dose once every 24 hours. Concurrently administer at least one other antituberculous drug to which the organisms have been demonstrated to be susceptible by appropriate in-vitro tests. Suitable drugs usually consist of those not previously used in the treatment of the patient. After 60 days of MYAMBUTOL administration, decrease the dose to 15 mg/kg (7mg/ lb) of body weight, and administer as a single oral dose once every 24 hours.

During the period when a patient is on a daily dose of 25 mg/kg, monthly eye examinations are advised.

See Table for easy selection of proper weight-dose tablet(s).

Weight-Dose Table
        15 mg/kg (7 mg/lb) Schedule  
  Weight Range   Daily Dose    
  Pounds      Kilograms   In mg
  Under 85 lbs.      Under 37 kg   500
  85 - 94.5      37 – 43   600
  95 - 109.5      43 – 50   700
  110 - 124.5      50 – 57   800
  125 - 139.5      57 – 64   900
  140 - 154.5      64 – 71   1000
  155 - 169.5      71 – 79   1100
  170 - 184.5      79 – 84   1200
  185 - 199.5      84 – 90   1300
  200 - 214.5      90 – 97   1400
  215 and Over      Over 97   1500
        25 mg/kg (11 mg/lb) Schedule  
  Under 85 lbs.      Under 38 kg   900
  85 - 92.5      38 - 42   1000
  93 - 101.5      42 - 45.5   1100
  102 - 109.5      45.5 – 50   1200
  110 - 118.5      50 – 54   .1300
  119 - 128.5      54 – 58   1400
  129 - 136.5      58 – 62   1500
  137 - 146.5      62 – 67   1600
  147 - 155.5      67 – 71   1700
  156 - 164.5      71 – 75   1800
  165 - 173.5      75 – 79   1900
  174 - 182.5      79 – 83   2000
  183 - 191.5      83 – 87   2100
  192 - 199.5      87 – 91   2200
  200 - 209.5      91 – 95   2300
  210 - 218.5      95 – 99   2400
  219 and Over      Over 99   2500
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