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Methocarbamol Side Effects

Medically reviewed by Drugs.com. Last updated on Dec 28, 2023.

Applies to methocarbamol: oral tablet. Other dosage forms:

Serious side effects of Methocarbamol

Along with its needed effects, methocarbamol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking methocarbamol:

Incidence not known

Get emergency help immediately if any of the following symptoms of overdose occur while taking methocarbamol:

Symptoms of Overdose

Other side effects of Methocarbamol

Some side effects of methocarbamol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

For Healthcare Professionals

Applies to methocarbamol: injectable solution, oral tablet.

General

The most commonly reported adverse reaction is headache.[Ref]

Cardiovascular

Some cardiovascular events may have been due to an overly rapid IV injection.

Most syncope cases resulted in spontaneous recovery; however, epinephrine, injectable steroids, and/or injectable antihistamines have been used in some cases.[Ref]

Frequency not reported: Syncope, hypotension, bradycardia, thrombophlebitis[Ref]

Hypersensitivity

Frequency not reported: Anaphylaxis

Nervous system

Convulsions have been reported with IV administration in patients with seizure disorders.[Ref]

Frequency not reported: Dizziness, lightheadedness, headache, drowsiness, mild muscular incoordination, metallic taste, nystagmus, sedation, seizures (including grand mal), tremor[Ref]

Psychiatric

Frequency not reported: Amnesia, confusion, insomnia, restlessness, anxiety

Local

Frequency not reported: Pain and sloughing at the injection site

Dermatologic

Frequency not reported: Urticaria, pruritus, rash, angioneurotic edema[Ref]

Gastrointestinal

Frequency not reported: Dyspepsia, nausea, vomiting, anorexia[Ref]

Other

Frequency not reported: Vertigo, fever[Ref]

Ocular

Frequency not reported: Blurred vision, conjunctivitis, diplopia[Ref]

Hematologic

Frequency not reported: Leukopenia[Ref]

Hepatic

Frequency not reported: Jaundice (including cholestatic jaundice)

Respiratory

Frequency not reported: Nasal congestion, bronchospasm[Ref]

Frequently asked questions

References

1. Product Information. Robaxin (methocarbamol). Whitehall-Robbins.

2. Multum Information Services, Inc. Expert Review Panel

3. CAMPBELL DJ, SHERBANIUK R, RIGBY J. FALSE POSITIVE REACTION DUE TO METHOCARBAMOL IN THE SCREENING TEST FOR VANILMANDELIC ACID (VMA). CLIN CHEM. 1964;10:447-50.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.